Fig 8.

Quercetin provided the protective effect in periodontitis via miR-21a-5p. A Schematic illustration of the animal experiment. B The 3D reconstruction and 2D cross-section images through Micro-CT analysis. C The results of CEJ-ABC distance analysis. D–H H&E, Masson and immunofluorescence staining of CD86, p-P65 and PDCD4. I–K Quantitative analysis of the fluorescent area of CD86, p-P65 and PDCD4 according to Fig. 8F–H. (ns, no significant difference; ^*p < 0.05, ^**p < 0.01, ^***p < 0.001; Data are represented as the mean ± SEM, n = 3)