Fig. 2
From: Alkylated EDTA potentiates antibacterial photodynamic activity of protoporphyrin
aEDTA improved PDT efficacy of PpIX against planktonic S. aureus. Exponentially growing S. aureus were preincubated separately with the combinations of PpIX (17.77 μM) and EDTA (0.5 mM) or aEDTAs (C8-EDTA, C12-EDTA, C14-EDTA, C15-EDTA, C16-EDTA, or C18-EDTA; 0.05 mM EDTA-eq.) for 1 h followed by illumination for 1 h, 2 h, or 3 h. The bacterium viability was determined by the standard plate count method; Data are presented as mean ± SD (n = 3). ****P < 0.0001, ***P < 0.001, **P < 0.01, *P < 0.1