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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: A versatile engineered extracellular vesicle platform simultaneously targeting and eliminating senescent stromal cells and tumor cells to promote tumor regression

Fig. 5

uPA-sEVs-siSrc induce apoptosis of tumor cells in vitro. (A) mRNA expression of Src in tumor cells with different treatments determined by RT-qPCR respectively. (B) Protein levels of p-Src and Src in tumor cells with different treatments determined by western blotting. (C) Cell viability analysis of tumor cells with different treatment for 48 h. (D) Caspase 3 activity of tumor cells after different treatments. (E, F) Flow cytometric examination (E) and quantitative analysis (F) of tumor cells apoptosis after different treatments. Data are displayed as the mean ± SD (n = 3). ***p<0.001; ****p<0.0001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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