Fig. 5
From: Tetrahedral framework nucleic acids for improving wound healing
tFNAs promote regulation of cell proliferation and migration. (A) tFNAs promote corneal epithelial wound healing. Reprinted with permission from Ref. [25]. (B) An in vitro scratch wound healing assay detected the effect of tFNAs at different concentrations on the migration of human corneal epithelial cells (HCECs). Reprinted with permission from Ref. [25]. (C) Schematic diagram of the regulatory effects of tFNAs on TGF-β1-induced fibrogenesis via interaction with Smad2/Smad3 signals. Reprinted with permission from Ref. [28]. (D) Images of scratch tests on HaCaT cells treated with different concentrations of tFNAs at 0 h, 6 h, and 24 h. Reprinted with permission from Ref. [28]. (E) Statistical analysis of scratch tests on HaCaT cells and HSF cells. Reprinted with permission from Ref. [28]