Fig. 6

Internalization kinetics of NPs. A Internalization of NPs into cardiomyocytes cells in a dose-dependent manner. Cardiomyocytes were treated with NPs at 0–5.0 mg/mL. B Internalization of NPs into cardiomyocytes in a time-dependent manner. Cardiomyocytes were treated with NPs for 0–120 min. The samples were analyzed under the laser scanning confocal microscopy. Fluorescence images were analyzed and processed with FluoView FV3000 software (Olympus). The same letter within column represents no significant difference (p > 0.05); different letters within column indicate significant difference (p < 0.05)