Fig. 8

Effect of NPs on oxidative stress. A Effect of NPs on ROS expression in H9c2 and AC16 cell models. B Effect of NPs on ROS in vivo. C Effect of NPs on oxidative phosphorylation status. D Effect of NPs on the permeability of mitochondrial membranes. E Effect of NPs on redox reactions. F Removal of ROS by MitoQ and Trolox. G MitoQ and Trolox increased cell survival. H MitoQ and Trolox reduced cellular senescence. I MitoQ and Trolox improved the cell cycle. J Trolox and MitoQ blocked cellular senescence. K Trolox and MitoQ reduced the expression of inflammatory factors. An asterisk indicates a significant interference