Fig. 3

The uptake of OXA@Fn by GL261/TR cell. A The expression of TfR1 in GL261/TR cells, BV2 cells and mouse primary neurons. B Schematic illustrations of co-culture GL261/TR cells, BV2 cells and mouse primary neurons in one cell culture dish. C Uptake of OXA@Fn by co-cultured GL261/TR cells, BV2 cells and mouse primary neurons. D The co-localization of OXA@Fn (red) and lysosome (green) in GL261/TR cells. E The uptake of OXA@Fn by GL261/TR cells in the presence of TfR1 antibody. F The typical flow cytometer diagrams of the uptake of OXA@Fn by GL261/TR cells in the presence of TfR1 antibody. G The co-localization of OXA@Fn (red) and TfR1 (green) in GL261/TR cells. The OXA@Fn concentration was equivalent to 45 μg Fn/ml. (n = 3, mean ± SD, ns: significant difference, **P < 0.01)