Fig. 9
Effect of OXA@Fn on the apoptosis and ferroptosis of orthotopic TMZ-resistant glioma. A The images of orthotopic TMZ-resistant glioma tissue slices stained with Ki67 antibody, γ-H2AX antibody and TUNEL assay kit. B The expression of apoptosis-related proteins in orthotopic TMZ-resistant glioma tissue. C Semi-quantitative analysis of apoptosis-related proteins. D The content of Fe2+ in orthotopic TMZ-resistant glioma tissue. E The expression of xCT and GPX4 in orthotopic TMZ-resistant glioma tissue. F The GSH level in orthotopic TMZ-resistant glioma tissue. G The images of orthotopic TMZ-resistant glioma tissue slices stained with ROS assay kit and GPX4 antibody. (n = 3, mean ± SD, *P <0.05,**P < 0.01)