Fig. 4

TK-MLP@(GP + EM) NPs inhibits lipid accumulation of macrophages. (A) Confocal fluorescence images and semi-quantitative analysis of DiI-oxLDL internalization in RAW264.7 cells. (B) Optical microscopy images and semi-quantitative analysis of ORO staining. (C-E) Western blot analysis of ABCA1 and ABCG1 on activated macrophages with different treatment. (F&G) Confocal fluorescence images of ABCA1 and ABCG1 on activated macrophages with different treatment. 1: Control;2: Model; 3: GP + EM; 4: TK-MLP@(GP + EM). Scale bar = 20 μm. n = 3, ^###P < 0.001 vs. the Control. *P < 0.05, ** P < 0.01, *** P < 0.001 vs. the Model