Fig. 6

The efficacy of TK-MLP@(GP + EM) NPs in ApoE^−/− mice fed HFD. (A) Photographs of the aortic arch. (B&C) The representative images of en face ORO-stained aortas and semi-quantitative analysis. n = 4. (D&E) ORO-stained frozen sections and semi-quantitative analysis of the aortic roots. (F-I) Representative immunohistochemistry staining photographs and semi-quantitative analysis with H&E and Masson trichrome. Scale bar = 200 μm. n = 3, ^###P < 0.001 vs. the Control. *** P < 0.001 vs. the Model.