Fig. 7

TK-MLP@(GP + EM) NPs can restore endothelial function in ApoE^−/− atherosclerosis mice. (A&B) Aortic root cross-sections were subjected to dihydroethidium staining for determination of the redox state with quantitative analysis of DHE MFI. (C&D) Aortic root cross-sections were conducted co-immunofluorescent staining with anti-CD31 (green) and ICAM-1 (red). (E&F) Immunofluorescence staining images of VE-cadherin in aortas from each group. Scale bar = 200 μm. n = 3, ^###P < 0.001 vs. the Control. ** P < 0.01, *** P < 0.001 vs. the Model.