Fig. 2
Preparation and characterization of PTMHs. (A) TEM images of Cu5.4O and (B) ZnO. (Scale bar: 100 nm). (C) The particle size distribution of Cu5.4O and ZnO nanoparticles. (D) Optical image of PTMH. (E) SEM images of PTMH. (Scale bar, left: 100 µm; right: 100 nm) (F) SEM images of ZnO@SA layer view after 3 days of incubation at 35°C. (Scale bar, left: 100 nm; right: 50 nm). (G) The stress‒strain curve of PNIPAM. (H) The elastic modulus (G’) and loss modulus (G’’) of PNIPAM. (I) Images of PNIPAM following incubation at 35 °C. (J) The test of ROS production of ZnO. (K) H2O2, (L) ·OH, and (M) O2·− scavenging capacity of different concentrations of Cu5.4O@PNIPAM. Data in K, L, and M represent the mean ± standard deviation (n = 5). n.s., no significance; one-way ANOVA. TEM, transmission electron microscopy; SA, sodium alginate; PNIPAM, poly(N-isopropylacrylamide); PTMH, programmed time-released multifunctional hydrogel; ANOVA, analysis of variance