Fig. 7
Schematic of the underlying mechanism of the effects of PTMH in impaired wounds healing. PTMH could combat bacterial infection by ZnO and alleviate inflammation via Cu5.4O ultrasmall nanozymes to improve the tissue repairing microenvironment, and ultimately promote impaired wound healing. IL, interleukin; PTMH, programmed time-released multifunctional hydrogel; ROS, reactive oxygen species; TNF-α, tumor necrosis factor-α