Fig. 5
Biosafety and biodistribution evaluation of Bi2S3/Ti3C2-TPP. a Serum biochemistry results involving ALB, ALT, AST, TP, GLOB, BUN, CREA, and A/G ratio obtained from mice injected with PBS (pH = 7.4, 10 mM) or Bi2S3/Ti3C2-TPP (20 mg kg-1) at 24 h. b The pictures of H&E dyed primary apparatus of mice involving heart, liver, spleen, lung, and kidney following various treatments (scale bar = 40 μm). c Blood circulation and d biodistribution of Bi2S3/Ti3C2-TPP (20 mg kg-1) after intravenous injection into U251 tumor-bearing mice by measuring Bi and Ti concentrations with ICP-MS. e In vivo CT pictures of U251 tumor-bearing mice before and after injecting with Bi2S3/Ti3C2-TPP (20 mg kg-1) intravenously. f In vitro CT images and CT values of Bi2S3/Ti3C2-TPP at various concentrations