Fig. 3

Modulation of proliferation, migration, and angiogenic marker expression of DPSCs using miR@TDNs. a Schematic diagram of the experimental design for miR@TDN-based modulation of the behavior of DPSCs. b CCK-8 assay for evaluating the cell viabilities of the DPSCs after intervention with different concentrations of miR@TDN, \(\hbox {n}=3\). c, d Results of applying the wound-healing and transwell assays to assess the migration abilities of the DPSCs. e Quantification of the relative invasion and migration cell number in (c), (d), \(\hbox {n}=3\). f Results of the WB analyses of the expression of vascular-related genes in DPSCs following miR, TDN, and miR@TDN interventions, \(\hbox {n}=3\). (h) The quantitative analysis of the related proteins in (f) is performed to determine the expression levels, \(\hbox {n}=3\). Data include the mean ± SD, statistical analysis: \(*p<0.05, **p<0.01, ***p<0.001\)