Scheme 1From: Kilogram scale facile synthesis and systematic characterization of a Gd-macrochelate as T1-weighted magnetic resonance imaging contrast agentA Schematic illustration for kilogram scale facile synthesis of Gd-HPMA macrochelates. B The Gd-HPMA macrochelate accumulates at the tumor through the EPR effect, which can be used for high contrast T1-weighted MRIBack to article page