Fig. 2
From: ECM stiffness affects cargo sorting into MSC-EVs to regulate their secretion and uptake behaviors
Substrate stiffness regulates the expression of biomolecules in MSCs. A, Volcano map demonstrating the regulation of MSCs proteins by substrate stiffness (|log2(FC)|≥ 0.58; p ≤ 0.05 is defined as difference, n = 3). B, Venn diagram of differential proteins regulated by substrate stiffness in MSCs (left) and MSC-EVs (right). C, Volcano map demonstrating the regulation of MSCs lipids by substrate stiffness ((|log2(FC)|≥ 1; p ≤ 0.05 is defined as a difference, n = 3). D, Venn diagram of differential lipids regulated by substrate stiffness in MSCs (left) and MSC-EVs (right)