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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Anti-EGFR ScFv functionalized exosomes delivering LPCAT1 specific siRNAs for inhibition of lung cancer brain metastases

Fig. 2

LPCAT1 expression patterns identified by scRNA seq analysis. (A) UMAP plot of cell subsets colored based on the major cell lineages and histological types including primary lung tumor, brain metastases tissues from GSE131907 dataset. (B) UMAP plot of all samples colored based on tissue types including lung, brain metastases, lymph node tissues and pleural fluid cells. (C-D)Average expression of LPCAT1 within lung tumor, brain metastases, lymph node tissues represented by UMAP plot and Violin Plot. tLung, lung tumor; mLymph node, lymph node metastases; mBrain, brain metastases

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