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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation

Fig. 5

GOQD-treated cell sheet-loaded GelMA facilitates periodontal bone defect repair in vivo. A Schematic diagram of the rat periodontal fenestration defect experiment. B Micro-CT cross-sectional and three-dimensional reconstruction of mandibular periodontal bone defects at 2 weeks and 4 weeks after surgery. C–H Comparisons of bone volume (BV) (C, F), bone volume fraction (BV/TV) (D, G) and bone surface density (E, H) at 2 weeks and 4 weeks (n = 6). I, J Images of HE staining (I) and Masson’s trichrome staining (J) of mandibular bone defects at 2 weeks and 4 weeks. OB old bone, NB new bone, RT root. NS P > 0.05, * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001

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