Fig. 6
A T2-weighted MR images of the tumor (white dashed circles indicate the tumor site) at different time points after injection of Fe3O4 or LFMP. B Semiquantitative analysis of T2-weighted MR images of the tumor at different time points after injection of Fe3O4 or LFMP. C Schematic illustration of the in vivo therapeutic process. D Body weight curves of tumor-bearing mice in each group during the treatment. E Relative tumor volume in different therapeutics groups. F Average tumor weight after 28 days of various treatments. G Survival curves of mice in each group. H Immunofluorescence staining of GPX4 of tumor bearing mice treated with Saline, LND, FMP + AMF, LFMP + AMF (scale bar = 50 μm). I Mean fluorescence intensity of GPX4. (J) Relative GSH levels in tumor tissues treated with Saline, LND, FMP + AMF, LFMP + AMF. Data are shown mean ± SD, n = 5. *p < 0.05, **p < 0.01, ***p < 0.005