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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Peripheral extracellular vesicles in neurodegeneration: pathogenic influencers and therapeutic vehicles

Fig. 3

Adipose tissue-derived EVs: messengers of metabolic and neurologic health. EVs deriving from adipose tissue present the potential to mediate both neuroprotective and neuropathogenic interactions. In the upper panel, EVs released from healthy adipose tissue are rich in beneficial adipokines, anti-inflammatory cytokines, and growth factors that collectively support neurogenesis, synaptic plasticity, and cognitive function. In the lower panel, in the metabolic disorders pathological state, adipose tissue becomes a source of EVs laden with proinflammatory adipokines, dysregulated miRNAs, and other metabolic by-products that can impair cognitive function

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Journal of Nanobiotechnology

ISSN: 1477-3155

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