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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Bacteria-driven nanosonosensitizer delivery system for enhanced breast cancer treatment through sonodynamic therapy-induced immunogenic cell death

Fig. 1

Preparation and characterization of HPNDs@EcN and corresponding functional verification. (A) Schematic diagram of HPNDs@EcN construction. (B) HPNDs observed by TEM. (C) EcN observed by SEM. (D) HPNDs@EcN observed by TEM. (E) UV-vis spectra of PNDs: PFP containing nanodroplets without HMME; HMME: hematoporphyrin monomethyl ether; EcN: Escherichia coli Nissle 1917; HPNDs: HMME/PFP nanodroplets; HPNDs@EcN: HMME/PFP nanodroplets linked Escherichia coli Nissle 1917. (F) HPNDs@EcN connection percentage detected at different reaction times. (G) Bacterial activity before and after HPNDs@EcN linkage. (H) Ultrasound imaging of HPNDs@EcN before and after ultrasound irradiation and its quantitative analysis. (ns: no significance, **** p < 0.0001)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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