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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Bacteria-driven nanosonosensitizer delivery system for enhanced breast cancer treatment through sonodynamic therapy-induced immunogenic cell death

Fig. 6

In vivo anti-tumor metastasis and ICD measurement. (A) Number of pulmonary metastases (a: Control; b: US; c: HPNDs@EcN; d, HPNDs@EcN + US). (B) Immunohistochemistry of CRT and HMGB1 in tumor tissue after various treatments. (C-D) Flow quantification of mature dendritic cells in tumor tissue after various treatments. (E, F) Flow quantification of infiltrated CD8 + T cells in tumor tissue after various treatments. (** p < 0.01, *** p < 0.001, **** p < 0.0001)

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