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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: DNA-based molecular classifiers for the profiling of gene expression signatures

Fig. 4

Profiling of the miRNA expression levels for the diagnosis of HCC. A In silico training of a minimal linear classifier to discriminate HCC from healthy individuals. Performance of the classifier with data from the training dataset, 94.7% and 95.6% of HCC from healthy individuals were classified correctly, with an AUC of 0.9904. B Performance of the classifier with data from the validation dataset, 96.0% and 94.2% of HCC from healthy individuals were diagnosed correctly, with an AUC of 0.9871. C Minimal linear classifier that included five miRNAs with weights ranging from  − 2.6 to 2.4. D Results of DNA-based molecular classifier for 10 cases each of HCC and healthy individuals use synthetic miRNAs

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