Fig. 7

a Key cellular and molecular mediators of inflammation in thrombus. b Odds ratios (ORs) and 95% confidence intervals (CIs) for the progression of atherosclerosis linked to traditional cardiovascular risk factors and CRP. c A comparison of the similarities and differences between the CANTOS, CIRT, and COLCOT clinical trials. d IL-6, e IL-8, f CRP, and g TNF-α levels in rats after various treatments. AMI, acute myocardial infarction; PE, pulmonary embolism; DVT, deep venous thrombosis; RR, relative risk; MACE, major adverse cardiovascular events (composite of cardiovascular death, myocardial infarction, or stroke); RCT, randomized controlled trial. The green arrow denotes a reduction, while the blue arrow indicates no change. G0, Control group; G1, Sham model group; G2, Model group; G3, Free ICG (0.35 mg/kg) + NIR group; G4, TPNs/ICG-PEG (7.8 mg/kg) + NIR group; G5, TPNs/ICG-cRGD (7.8 mg/kg) + NIR group. n = 6, mean ± SD