Fig. 2From: An exosomal strategy for targeting cancer-associated fibroblasts mediated tumors desmoplastic microenvironmentsSchematic illustration of engineered exosomes targeting CAFs mediated desmoplastic microenvironments to exert theranostic potential on desmoplastic tumors models. After injection, antigen and theranostic agents-loaded exosomes can target CAFs mediated desmoplastic microenvironments to exert theranostic potential via stimulating the activation of CD8+T cell, removing ECM, inactivating CAFs, inhibiting the signal transduction of CAF-tumor cells and CAF-immune cells crosstalk, and imaging in vivoBack to article page