Circulating tumor cell-derived exosome–transmitted long non-coding RNA TTN-AS1 can promote the proliferation and migration of cholangiocarcinoma cells

Zhou, Xu; Kong, Xiaohan; Lu, Jun; Wang, Heng; Liu, Meng; Zhao, Shuchao; Xia, Zhaozhi; Liu, Qinggong; Sun, Hongrui; Gao, Xin; Ma, Chaoqun; Niu, Zheyu; Yang, Faji; Song, Xie; Gao, Hengjun; Zhang, Shizhe; Zhu, Huaqiang

doi:10.1186/s12951-024-02459-8

Fig. 5

From: Circulating tumor cell-derived exosome–transmitted long non-coding RNA TTN-AS1 can promote the proliferation and migration of cholangiocarcinoma cells

Expression of LncRNA TTN-AS1 in CCA cell lines, tissues, serum, and serum exosomes. (A) Detection of LncRNA expression in QBC939 and HIBEC cell-derived exosomes by qRT-PCR; (B) Detection of TTN-AS1 expression in cholangiocarcinoma cell lines by qRT-PCR; (C) Detection of TTN-AS1 expression in cholangiocarcinoma tissues and adjacent tissues by qRT-PCR; (D) Detection of TTN-AS1 expression in blood samples of cholangiocarcinoma patients and healthy individuals by qRT-PCR; (E) Detection of TTN-AS1 expression in serum exosomes of cholangiocarcinoma patients and healthy individuals by qRT-PCR; (F) ROC curve of TTN-AS1 expression in cholangiocarcinoma tumor tissues of patients; (G) ROC curve of TTN-AS1 expression in blood samples of cholangiocarcinoma patients; (H) ROC curve of TTN-AS1 expression in serum exosomes of cholangiocarcinoma patients

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Fig. 5

Journal of Nanobiotechnology

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