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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Synovium microenvironment-responsive injectable hydrogel inducing modulation of macrophages and elimination of synovial fibroblasts for enhanced treatment of rheumatoid arthritis

Fig. 6

In vivo treatment efficacy of BiPM@IOK hydrogel. A Representative infrared thermal images of right hind ankle joints of AIA rats with different treatments under NIR (808 nm, 1 W/cm2) irradiation for 5 min. B Temperature increase curves according to (A). Representative images of right hind paws (C) and paws swelling degree (D) of normal and AIA rats with different treatments, ***, p < 0.001. Concentration of TNF-α (E) and IL-1β (F) of synovium tissue samples detected by ELISA kit, ***, p < 0.001. G Safranin O staining of joints after various administrations

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