Nanozymes | Oral disease | Antibacterial mechanism and function | Reference |
---|---|---|---|
Ferumoxytol (Fer) | Tooth decay | Researchers Investigated the use of topical Fer as a nanozyme to prevent dental caries (tooth decay) by killing bacteria and disrupting biofilm | |
Dex-NZM | Severe caries | Researchers presented dextran-coated iron oxide nanoparticles (Dex-NZM) that exhibit potent catalytic (POD-like) activity at acidic pH levels, selectively target biofilms to prevent severe caries, and do so in vivo without affecting adjacent oral tissues | [95] |
Glucose-OXD | Dental caries | Utilize a nanohybrid system to increase intrinsic H2O2 production and induce pH-dependent ROS generation to effectively target biofilm virulence under pathological (sugar-rich/acidic) | [96] |
Iron oxide nanozymes or iron sulfide nanozymes | Dental caries | Integrating H2O2-producing bacteria and FeSN could potentially offer a novel approach to eradicating oral biofilms during dental caries therapy | [98] |