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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: LIFU/MMP-2 dual-responsive release of repurposed drug disulfiram from nanodroplets for inhibiting vasculogenic mimicry and lung metastasis in triple-negative breast cancer

Fig. 3

Penetration of drugs delivered by PFP@PDM-PEG into 4T1 tumor spheroids and the tumor parenchyma. A In vitro confocal microscopy images of the penetration of FITC-labeled PFP@PDM-PEG into a 4T1 tumor spheroid model and C the corresponding fluorescence intensities. Images were obtained from the top to the middle of the spheroids every 10 mm; scale bar: 50 μm. B CLSM images of the distribution of DiI-labeled PFP@PDM-PEG in tumor cryosections and (D) the corresponding fluorescence intensities; scale bar: 1 mm (n = 3, t-test, ***p < 0.001)

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