Fig. 6

In vivo antitumor therapy and inhibition of distant metastasis. A Schematic of the in vivo experimental design. B Tumor growth curves. C Tumor volumes on Day 14. D Tumor growth inhibition values. E Number of macroscopically visible pulmonary metastases in the different treatment groups. F Representative H&E staining images of lungs with metastatic deposits (black circles) following treatment; scale bars: 10 μm (above) and 40 μm (below) (n = 5, mean ± SD, t test, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.001)