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  1. Bone defects remain a significant challenge in clinical orthopedics, but no targeted medication can solve these problems. Inspired by inflammatory targeting properties of macrophages, inflammatory microenviron...

    Authors: Peng Xue, Zhiyong Chang, Hao Chen, Hongzhong Xi, Xiaoxue Tan, Shuai He, Haishi Qiao, Xiaohong Jiang, Xin Liu and Bin Du
    Citation: Journal of Nanobiotechnology 2024 22:87
  2. The human monkeypox virus (Mpox) is classified as a member of the Poxviridae family and belongs to the Orthopoxvirus genus. Mpox possesses double-stranded DNA, and there are two known genetic clades: those ori...

    Authors: Mohammad Natami, Amirsasan Gorgzadeh, Arsalan Gholipour, Seyedeh Narges Fatemi, Nima Firouzeh, Maryam Zokaei, Saad Hasan Mohammed Ali, Hadis Kheradjoo, Somayeh Sedighi, Omid Gholizadeh and Shaylan Kalavi
    Citation: Journal of Nanobiotechnology 2024 22:86
  3. Impaired collateral formation is a major factor contributing to poor prognosis in type 2 diabetes mellitus (T2DM) patients with atherosclerotic cardiovascular disease. However, the current pharmacological trea...

    Authors: Yixuan Wang, Feifei Li, Linshuang Mao, Yu Liu, Shuai Chen, Jingmeng Liu, Ke Huang, Qiujing Chen, Jianrong Wu, Lin Lu, Yuanyi Zheng, Weifeng Shen, Tao Ying, Yang Dai and Ying Shen
    Citation: Journal of Nanobiotechnology 2024 22:85
  4. Immunotherapy with clodronate-encapsulated liposomes, which induce macrophage depletion, has been studied extensively. However, previously reported liposomal formulation-based drugs (Clodrosome® and m-Clodrosome®

    Authors: Tae Hyeon Choi, Ran Ji Yoo, Ji Yong Park, Ji Yoon Kim, Young Chan Ann, Jeongbin Park, Jin Sil Kim, Kyuwan Kim, Yu Jin Shin, Yong Jin Lee, Kyo Chul Lee, Jisu Park, Hyewon Chung, Seung Hyeok Seok, Hyung-Jun Im and Yun-Sang Lee
    Citation: Journal of Nanobiotechnology 2024 22:83
  5. The advancement of biomaterials with antimicrobial and wound healing properties continues to present challenges. Macrophages are recognized for their significant role in the repair of infection-related wounds....

    Authors: Xiaogang Bao, Shicheng Huo, Zhenhua Wang, Shengyan Yang, Linyun Dou, Yifei Liu, Jian Huang, Chang Cai, Bin Fang and Guohua Xu
    Citation: Journal of Nanobiotechnology 2024 22:80
  6. Osteoarthritis (OA) is a degenerative disease that significantly impairs quality of life. There is a pressing need for innovative OA therapies. While small extracellular vesicles (sEVs) show promising therapeu...

    Authors: Tianqi Wang, Hongqi Zhao, Yi Zhang, Yanshi Liu, Jialin Liu, Ge Chen, Ke Duan, Zhong Li, Hoi Po James Hui and Jiyuan Yan
    Citation: Journal of Nanobiotechnology 2024 22:79
  7. Bacterial biosynthesis of fluorescent nanoparticles or quantum dots (QDs) has emerged as a unique mechanism for heavy metal tolerance. However, the physiological pathways governing the removal of QDs from bact...

    Authors: Felipe Valenzuela-Ibaceta, Nicolás Torres-Olea, Javiera Ramos-Zúñiga, Claudio Dietz-Vargas, Claudio A. Navarro and José M. Pérez-Donoso
    Citation: Journal of Nanobiotechnology 2024 22:78
  8. Authors: Blerina Shkodra, Christian Kretzer, Paul M. Jordan, Paul Klemm, Andreas Koeberle, David Pretzel, Erden Banoglu, Stefan Lorkowski, Maria Wallert, Stephanie Höppener, Steffi Stumpf, Antje Vollrath, Stephanie Schubert, Oliver Werz and Ulrich S. Schubert
    Citation: Journal of Nanobiotechnology 2024 22:77

    The original article was published in Journal of Nanobiotechnology 2020 18:73

  9. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with different antigenic variants, has posed a significant threat to public health. It is urgent to develop inhalable vaccines, instead of injectab...

    Authors: Shuqi Wang, Peiyang Ding, Lingli Shen, Daopeng Fan, Hanghang Cheng, Jian Huo, Xin Wei, Hua He and Gaiping Zhang
    Citation: Journal of Nanobiotechnology 2024 22:76
  10. The capacity to identify small amounts of pathogens in real samples is extremely useful. Herein, we proposed a sensitive platform for detecting pathogens using cyclic DNA nanostructure@AuNP tags (CDNA) and a c...

    Authors: Yunju Xiao, Shihua Luo, Jiuxiang Qiu, Ye Zhang, Weijiang Liu, Yunhu Zhao, YiTong Zhu, Yangxi Deng, Mengdi Lu, Suling Liu, Yong Lin, Aiwei Huang, Wen Wang, Xuejiao Hu and Bing Gu
    Citation: Journal of Nanobiotechnology 2024 22:75
  11. Due to its unique structure, articular cartilage has limited abilities to undergo self-repair after injury. Additionally, the repair of articular cartilage after injury has always been a difficult problem in t...

    Authors: Zhengang Ding, Zineng Yan, Xun Yuan, Guangzhao Tian, Jiang Wu, Liwei Fu, Han Yin, Songlin He, Chao Ning, Yazhe Zheng, Zhichao Zhang, Xiang Sui, Libo Hao, Yuting Niu, Shuyun Liu, Weimin Guo…
    Citation: Journal of Nanobiotechnology 2024 22:74
  12. The formation of blood vessel system under a relatively higher Cu2+ ion level is an indispensable precondition for tumor proliferation and migration, which was assisted in forming the tumor immune microenvironmen...

    Authors: Wenling Li, Huan Xin, Wenjuan Gao, Pengjun Yuan, Feixue Ni, Jingyi Ma, Jingrui Sun, Jianmin Xiao, Geng Tian, Lu Liu and Guilong Zhang
    Citation: Journal of Nanobiotechnology 2024 22:73
  13. Osteoarthritis (OA) is one of the most prevalent chronic musculoskeletal diseases among the elderly population. In this study, macrophage-derived exosomes were isolated and identified. Exosomes were subjected ...

    Authors: Yufan Qian, Genglei Chu, Lei Zhang, Zhikai Wu, Qiuyuan Wang, Jiong Jiong Guo and Feng Zhou
    Citation: Journal of Nanobiotechnology 2024 22:72
  14. Moringa oleifera is one of the popular functional foods that has been tremendously exploited for synthesis of a vast majority of metal nanoparticles (NPs). The diverse secondary metabolites present in this plant ...

    Authors: Haribalan Perumalsamy, Sri Renukadevi Balusamy, Johan Sukweenadhi, Sagnik Nag, Davoodbasha MubarakAli, Mohamed El-Agamy Farh, Hari Vijay and Shadi Rahimi
    Citation: Journal of Nanobiotechnology 2024 22:71
  15. Authors: Zijian Su, Yibo Zhang, Jieqiong Cao, Yuanmeng Sun, Yuling Cai, Bihui Zhang, Liu He, Zilei Zhang, Junye Xie, Qilin Meng, Lin Luo, Fu Li, Jingsheng Li, Jinting Zhang, Xiaojia Chen and An Hong
    Citation: Journal of Nanobiotechnology 2024 22:70

    The original article was published in Journal of Nanobiotechnology 2023 21:55

  16. Neutrophil extracellular traps (NETs), antibacterial weapons of neutrophils (NEs), have been found to play a crucial role in cancer metastasis in recent years. More and more cancer research is focusing on anti...

    Authors: Li-na Liu, Chen Chen, Wen-jie Xin, Qiang Li, Chao Han and Zi-chun Hua
    Citation: Journal of Nanobiotechnology 2024 22:69
  17. Plant-derived nanovesicles (PDNVs) are a novelty in medical and agrifood environments, with several studies exploring their functions and potential applications. Among fruits, apples (sp. Malus domestica) have gr...

    Authors: Martina Trentini, Ilaria Zanolla, Elena Tiengo, Federica Zanotti, Eduardo Sommella, Fabrizio Merciai, Pietro Campiglia, Danilo Licastro, Margherita Degasperi, Luca Lovatti, Massimo Bonora, Alberto Danese, Paolo Pinton and Barbara Zavan
    Citation: Journal of Nanobiotechnology 2024 22:68
  18. The transplantation of exosomes derived from human adipose-derived mesenchymal stem cells (hADSCs) has emerged as a prospective cellular-free therapeutic intervention for the treatment of neurodevelopmental di...

    Authors: Yu Fu, Yuan-lin Zhang, Rong-qi Liu, Meng-meng Xu, Jun-ling Xie, Xing-liao Zhang, Guang-ming Xie, Yao-ting Han, Xin-Min Zhang, Wan-ting Zhang, Jing Zhang and Jun Zhang
    Citation: Journal of Nanobiotechnology 2024 22:66
  19. The intestinal development in early life is profoundly influenced by multiple biological components of breast milk, in which milk-derived extracellular vesicles (mEVs) contain a large amount of vertically tran...

    Authors: Dongdong Lu, Yisi Liu, Luyuan Kang, Xiangyu Zhang, Jie Hu, Hao Ye, Bingxu Huang, Yujun Wu, Jinbiao Zhao, Zhaolai Dai, Junjun Wang and Dandan Han
    Citation: Journal of Nanobiotechnology 2024 22:65
  20. A large number of Fusobacterium nucleatum (Fn) are present in colorectal cancer (CRC) tissues of patients who relapse after chemotherapy, and Fn has been reported to promote oxaliplatin and 5-FU chemoresistance i...

    Authors: Bingqing Hui, Chenchen Zhou, Yetao Xu, Rui Wang, Yuwen Dong, Yirui Zhou, Jie Ding, Xiao Zhang, Jian Xu and Yanhong Gu
    Citation: Journal of Nanobiotechnology 2024 22:62
  21. Despite recent advancements in cancer treatment, this disease still poses a serious threat to public health. Vaccines play an important role in preventing illness by preparing the body's adaptive and innate im...

    Authors: Zhe Sun, Hui Zhao, Li Ma, Yanli Shi, Mei Ji, Xiaodong Sun, Dan Ma, Wei Zhou, Tao Huang and Dongsheng Zhang
    Citation: Journal of Nanobiotechnology 2024 22:61
  22. Mesenchymal stem cells/stromal cells (MSCs)-derived extracellular vesicles (EVs) mediate pro-regenerative effects in damaged ischemic tissues by regulating angiogenesis. MSCs-EVs modulate functions of cells in...

    Authors: Anna Łabędź-Masłowska, Luisa Vergori, Sylwia Kędracka-Krok, Elżbieta Karnas, Sylwia Bobis-Wozowicz, Małgorzata Sekuła-Stryjewska, Michał Sarna, Ramaroson Andriantsitohaina and Ewa K. Zuba-Surma
    Citation: Journal of Nanobiotechnology 2024 22:60
  23. Coordination between osteo-/angiogenesis and the osteoimmune microenvironment is essential for effective bone repair with biomaterials. As a highly personalized and precise biomaterial suitable for repairing c...

    Authors: Shi-Yuan Yang, Yu-Ning Zhou, Xing-Ge Yu, Ze-Yu Fu, Can-Can Zhao, Yue Hu, Kai-Li Lin and Yuan-Jin Xu
    Citation: Journal of Nanobiotechnology 2024 22:59
  24. Multivalent drugs targeting homo-oligomeric viral surface proteins, such as the SARS-CoV-2 trimeric spike (S) protein, have the potential to elicit more potent and broad-spectrum therapeutic responses than mon...

    Authors: Qin Qin, Xinyi Jiang, Liyun Huo, Jiaqiang Qian, Hongyuan Yu, Haixia Zhu, Wenhao Du, Yuhui Cao, Xing Zhang and Qiang Huang
    Citation: Journal of Nanobiotechnology 2024 22:58
  25. Extracellular vesicles have shown promising tissue recovery-promoting effects, making them increasingly sought-after for their therapeutic potential in wound treatment. However, traditional extracellular vesic...

    Authors: Yi Zheng, Chuqiao Pan, Peng Xu and Kai Liu
    Citation: Journal of Nanobiotechnology 2024 22:57
  26. Diabetic retinopathy (DR) is a vision-threatening diabetic complication that is characterized by microvasculature impairment and immune dysfunction. The present study demonstrated that M2 microglia intensively...

    Authors: Xingxing Wang, Changlin Xu, Cunxin Bian, Pengfei Ge, Jie Lei, Jingfan Wang, Tianhao Xiao, Yuanyuan Fan, Qinyuan Gu, Hong-Ying Li, Jingyi Xu, Zizhong Hu and Ping Xie
    Citation: Journal of Nanobiotechnology 2024 22:56
  27. Exosomes are nanoscale extracellular vesicles (30–160 nm) with endosome origin secreted by almost all types of cells, which are considered to be messengers of intercellular communication. Cancerous exosomes se...

    Authors: Bowen Jiang, Tenghua Zhang, Silan Liu, Yan Sheng and Jiaming Hu
    Citation: Journal of Nanobiotechnology 2024 22:55

    The Correction to this article has been published in Journal of Nanobiotechnology 2024 22:82

  28. The treatment of critical-size bone defects with irregular shapes remains a major challenge in the field of orthopedics. Bone implants with adaptability to complex morphological bone defects, bone-adhesive pro...

    Authors: Shiqi Zhou, Cairong Xiao, Lei Fan, Jinghong Yang, Ruihan Ge, Min Cai, Kaiting Yuan, Changhao Li, Ross William Crawford, Yin Xiao, Peng Yu, Chunlin Deng, Chengyun Ning, Lei Zhou and Yan Wang
    Citation: Journal of Nanobiotechnology 2024 22:54
  29. Enzyme therapy based on differential metabolism of cancer cells has demonstrated promising potential as a treatment strategy. Nevertheless, the therapeutic benefit of reported enzyme drugs is compromised by th...

    Authors: Xiuhui Tang, Lijuan Zhang, Mingwang Huang, Fang Wang, Guiqiu Xie, Rui Huo and Renjun Gao
    Citation: Journal of Nanobiotechnology 2024 22:53
  30. Bacterial cystitis, a commonly occurring urinary tract infection (UTI), is renowned for its extensive prevalence and tendency to recur. Despite the extensive utilization of levofloxacin as a conventional thera...

    Authors: Yi Yang, Guang-Wei Yang, Jian-Juan Lu, Hao-Ran Chen, Ya-Qin Guo, Ning Yang, Yun-Zhu Zhu, Xiao-Qiang Liu, Ting-Ting Su, Yan-Yan Liu, Liang Yu, Ya-Sheng Li, Li-Fen Hu and Jia-Bin Li
    Citation: Journal of Nanobiotechnology 2024 22:52
  31. Allergic rhinitis (AR) is a prevalent immune-related allergic disease, and corticosteroid nasal sprays serve as the primary treatment for this patient population. However, their short duration of efficacy and ...

    Authors: Li Dai, Bin Liu, Jiangtao Lin, Yongquan Jiang, Yuanyuan Li, Zhuowei Yao, Silin Shen, Yiming Jiang, Yourong Duan and Jiping Li
    Citation: Journal of Nanobiotechnology 2024 22:51
  32. Obesity is a major risk to human health. Adipogenesis is blocked by α-tocopherol and conjugated linoleic acid (CLA). However, their effect at preventing obesity is uncertain. The effectiveness of the bioactive...

    Authors: Ching-Yun Hsu, Chia-Chih Liao, Zih-Chan Lin, Ahmed Alalaiwe, Erica Hwang, Tzu-Wei Lin and Jia-You Fang
    Citation: Journal of Nanobiotechnology 2024 22:50
  33. Inflammatory bowel disease (IBD) is closely linked to the homeostasis of the intestinal environment, and exosomes can be used to treat IBD due to their high biocompatibility and ability to be effectively absor...

    Authors: Song Yang, Wenjing Li, Xueyuan Bai, Giada Di Nunzio, Liangliang Fan, Yueming Zhao, Limei Ren, Ronghua Zhao, Shuai Bian, Meichen Liu, Yuchi Wei, Daqing Zhao and Jiawen Wang
    Citation: Journal of Nanobiotechnology 2024 22:48
  34. The osteoimmune microenvironment induced by implants plays a significant role in bone regeneration. It is essential to efficiently and timely switch the macrophage phenotype from M1 to M2 for optimal bone heal...

    Authors: Yubo Shi, Weidong Tao, Wenjing Yang, Lei Wang, Zhennan Qiu, Xiaoli Qu, Jingyi Dang, Jiankang He and Hongbin Fan
    Citation: Journal of Nanobiotechnology 2024 22:47
  35. Amorphous silica nanoparticles (ASNP) are among the nanomaterials that are produced in large quantities. ASNP have been present for a long time in several fast-moving consumer products, several of which imply ...

    Authors: Massimiliano G. Bianchi, Martina Chiu, Giuseppe Taurino, Enrico Bergamaschi, Francesca Turroni, Leonardo Mancabelli, Giulia Longhi, Marco Ventura and Ovidio Bussolati
    Citation: Journal of Nanobiotechnology 2024 22:45
  36. The COVID-19 pandemic is a persistent global threat to public health. As for the emerging variants of SARS-CoV-2, it is necessary to develop vaccines that can induce broader immune responses, particularly vacc...

    Authors: Ruiqi Li, Zejie Chang, Hongliang Liu, Yanan Wang, Minghui Li, Yilan Chen, Lu Fan, Siqiao Wang, Xueke Sun, Siyuan Liu, Anchun Cheng, Peiyang Ding and Gaiping Zhang
    Citation: Journal of Nanobiotechnology 2024 22:44
  37. The central nervous system (CNS) maintains homeostasis with its surrounding environment by restricting the ingress of large hydrophilic molecules, immune cells, pathogens, and other external harmful substances...

    Authors: Fang Han, Jiahao Gao, Guanglei Lv, Tao Liu, Qingfeng Hu, Meilin Zhu, Zunguo Du, Jing Yang, Zhenwei Yao, Xiangming Fang, Dalong Ni and Jiawen Zhang
    Citation: Journal of Nanobiotechnology 2024 22:43
  38. Authors: Yanli Zhu, Jikai Wang, Chengxiao Fu, Shuangquan Liu, Pragati Awasthi, Pengfei Zeng, Danjun Chen, Yiyang Sun, Ziyi Mo and Hailing Liu
    Citation: Journal of Nanobiotechnology 2024 22:42

    The original article was published in Journal of Nanobiotechnology 2023 21:475

  39. Malignancy is a major public health problem and among the leading lethal diseases worldwide. Although the current tumor treatment methods have therapeutic effect to a certain extent, they still have some short...

    Authors: Qian Yang, Shisheng Li, Haibo Ou, Yuming Zhang, Gangcai Zhu, Shaohong Li and Lanjie Lei
    Citation: Journal of Nanobiotechnology 2024 22:41
  40. Currently, many types of non-linear topological structure polymers, such as brush-shaped, star, branched and dendritic structures, have captured much attention in the field of gene delivery and nanomedicine. C...

    Authors: Chenfei Wang, Wei He, Feifei Wang, Haiyang Yong, Tao Bo, Dingjin Yao, Yitong Zhao, Chaolan Pan, Qiaoyu Cao, Si Zhang and Ming Li
    Citation: Journal of Nanobiotechnology 2024 22:40
  41. The design of DNA materials with specific nanostructures for biomedical tissue engineering applications remains a challenge. High-dimensional DNA nanomaterials are difficult to prepare and are unstable; moreov...

    Authors: Songlin He, Haotian Deng, Peiqi Li, Qinyu Tian, Yongkang Yang, Jingjing Hu, Hao Li, Tianyuan Zhao, Hongkun Ling, Yin Liu, Shuyun Liu and Quanyi Guo
    Citation: Journal of Nanobiotechnology 2024 22:39

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