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  1. Colorectal cancer (CRC) has high incidence and mortality rates and is one of the most common cancers of the digestive tract worldwide. Metastasis and drug resistance are the main causes of cancer treatment fai...

    Authors: Linjin Xiong, Yumeng Wei, Qiang Jia, Jinglin Chen, Tao Chen, Jiyuan Yuan, Chao Pi, Huiyang Liu, Jia Tang, Suyu Yin, Ying Zuo, Xiaomei Zhang, Furong Liu, Hongru Yang and Ling Zhao
    Citation: Journal of Nanobiotechnology 2023 21:143
  2. Since the end of 2019, a highly contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has deprived numerous lives worldwide, called COVID-19. Up to date, omicron is the late...

    Authors: Zhi Chen, Chenshuo Wu, Yuxuan Yuan, Zhongjian Xie, Tianzhong Li, Hao Huang, Shuang Li, Jiefeng Deng, Huiling Lin, Zhe Shi, Chaozhou Li, Yabin Hao, Yuxuan Tang, Yuehua You, Omar A. Al-Hartomy, Swelm Wageh…
    Citation: Journal of Nanobiotechnology 2023 21:141
  3. Atherosclerosis is one of the most common types of cardiovascular disease and is driven by lipid accumulation and chronic inflammation in the arteries, which leads to stenosis and thrombosis. Researchers have ...

    Authors: Siyu Chen, Yuan Su, Manjin Zhang, Yulin Zhang, Peiming Xiu, Wei Luo, Qiuxia Zhang, Xinlu Zhang, Hongbin Liang, Alex Pui-Wai Lee, Longquan Shao and Jiancheng Xiu
    Citation: Journal of Nanobiotechnology 2023 21:140
  4. Topical anticancer drugs offer a potential therapeutic modality with high compliance for treating cutaneous squamous cell carcinoma (cSCC). However, the existing topical treatments for cSCC are associated with...

    Authors: Ying Li, Zongguang Tai, Jinyuan Ma, Fengze Miao, Rujuan Xin, Cuie Shen, Min Shen, Quangang Zhu and Zhongjian Chen
    Citation: Journal of Nanobiotechnology 2023 21:139
  5. Since the successful clinical trial of AuroShell for photothermal therapy, there is currently intense interest in developing gold-based core-shell structures with near-infrared (NIR) absorption ranging from NI...

    Authors: Ming Chen, Xiao-Tong Chen, Lian-Ying Zhang, Wei Meng, Yong-Jian Chen, Ying-Shan Zhang, Zhi-Cong Chen, Hui-Min Wang, Chun-Mei Luo, Xiu-Dong Shi, Wen-Hua Zhang, Mao-Sheng Wang and Jin-Xiang Chen
    Citation: Journal of Nanobiotechnology 2023 21:138
  6. It is essential to develop ultrasensitive biosensors for cancer detection and treatment monitoring. In the development of sensing platforms, metal-organic frameworks (MOFs) have received considerable attention...

    Authors: Suliman Khan, William C. Cho, Afrooz Sepahvand, Sara Haji Hosseinali, Arif Hussain, Mohammad Mahdi Nejadi Babadaei, Majid Sharifi, Mojtaba Falahati, Laila Abdulmohsen Jaragh-Alhadad, Timo L. M. ten Hagen and Xin Li
    Citation: Journal of Nanobiotechnology 2023 21:136
  7. Senescence of vascular smooth muscle cells (VSMCs) contributes to the formation of abdominal aortic aneurysm (AAA). Although mesenchymal stem cell exosomes (MSC-EXO) have been confirmed to restrict the develop...

    Authors: Yuxiao Zhang, Xiaoran Huang, Tucheng Sun, Linli Shi, Baojuan Liu, Yimei Hong, Qing-Ling Fu, Yuelin Zhang and Xin Li
    Citation: Journal of Nanobiotechnology 2023 21:135
  8. Posterior capsular opacification (PCO) is the most common complication after cataract surgery. Present strategies can’t meet the clinical needs of long-term prevention. This research reports a novel intraocula...

    Authors: Yueze Hong, Qiuna Fang, Ting Bai, Peiyi Zhao, Yuemei Han and Quankui Lin
    Citation: Journal of Nanobiotechnology 2023 21:134
  9. Nanotechnology-enabled sensors or nanosensors are emerging as promising new tools for various in-vivo life science applications such as biosensing, components of delivery systems, and probes for spatial bioimagin...

    Authors: Michael A. Lee, Xiaojia Jin, Sureshkumar Muthupalani, Naveed A. Bakh, Xun Gong and Michael S. Strano
    Citation: Journal of Nanobiotechnology 2023 21:133
  10. Photothermal therapy has shown great promise for cancer treatment and second near-infrared (NIR-II) -absorbing particles could further improve its precision and applicability due to its superior penetration de...

    Authors: Han Xu, Huaping Deng, Xiaoqian Ma, Yushuo Feng, Ruizhen Jia, Yiru Wang, Yaqing Liu, Wenli Li, Shanshan Meng and Hongmin Chen
    Citation: Journal of Nanobiotechnology 2023 21:132

    The Correction to this article has been published in Journal of Nanobiotechnology 2023 21:179

  11. Magnetic hyperthermia (MHT)-mediated thermal ablation therapy has promising clinical applications in destroying primary tumours. However, traditional MHT still presents the challenges of damage to normal tissu...

    Authors: Qiaoxi Qin, Yang Zhou, Pan Li, Ying Liu, Ruxi Deng, Rui Tang, Nianhong Wu, Li Wan, Ming Ye, Hong Zhou and Zhiming Wang
    Citation: Journal of Nanobiotechnology 2023 21:131
  12. TMVP1 is a novel tumor targeting polypeptide screened by our laboratory with a core sequence of five amino acids LARGR. It specially binds to vascular endothelial growth factor receptor-3 (VEGFR-3), which is m...

    Authors: Xueqian Wang, Geyang Dai, Guiying Jiang, Danya Zhang, Ling Wang, Wen Zhang, Huang Chen, Teng Cheng, Ying Zhou, Xiao Wei, Fei Li, Ding Ma, Songwei Tan, Rui Wei and Ling Xi
    Citation: Journal of Nanobiotechnology 2023 21:130
  13. Excessive oxidative stress at the wound sites always leads to a prolonged healing and even causes chronic inflammatory wounds. Therefore, antioxidative dressings with multiple features are desired to improve w...

    Authors: Xuan Chen, Yihui Zhang, Wei Yu, Wenkai Zhang, Haozheng Tang and Wei-En Yuan
    Citation: Journal of Nanobiotechnology 2023 21:129
  14. Chronic non-healing wounds, a prevalent complication of diabetes, are associated with increased mortality in diabetic patients. Excessive accumulation of M1 macrophages in diabetic wounds promotes inflammation...

    Authors: Wenzheng Xia, Yunhan Liu, Xingyu Jiang, Minxiong Li, Shengwu zheng, Zewei Zhang, Xin Huang, Shenying Luo, Yimin Khoong, Meng Hou and Tao Zan
    Citation: Journal of Nanobiotechnology 2023 21:128
  15. Tumor microenvironment is characterized by the high concentration of reactive oxygen species (ROS), which is an effective key used to open the Pandora’s Box against cancer. Herein, a tumor-targeted nanosystem ...

    Authors: Xinmin Zheng, Xiang Li, Siyu Meng, Guolin Shi, Hui Li, Huiping Du, Liangliang Dai and Hui Yang
    Citation: Journal of Nanobiotechnology 2023 21:127
  16. Currently, high doses of cytarabine arabinoside (Ara-C)-based combined chemotherapy are commonly used in acute myeloid leukemia (AML) therapy, but severe adverse effects and poor suppression effects in leukemi...

    Authors: Xinzhou Wu, Zhouguang Jiao, Junying Zhang, Feng Li and Yuhua Li
    Citation: Journal of Nanobiotechnology 2023 21:126
  17. Osteoporosis (OP) is a metabolic bone disease characterized by decreased bone mass and increased bone fragility. The imbalance of bone homeostasis modulated by osteoclasts and osteoblasts is the most crucial p...

    Authors: Yueqi Chen, Chuan Yang, Qijie Dai, Jiulin Tan, Ce Dou and Fei Luo
    Citation: Journal of Nanobiotechnology 2023 21:125
  18. One-third of the world's population has anemia, contributing to higher morbidity and death and impaired neurological development. Conventional anemia treatment raises concerns about iron bioavailability and ga...

    Authors: Călina Ciont, Amalia Mesaroș, Oana Lelia Pop and Dan Cristian Vodnar
    Citation: Journal of Nanobiotechnology 2023 21:124
  19. Doxorubicin (Dox) has been recommended in clinical guidelines for the standard-of-care treatment of breast cancer. However, Dox therapy faces challenges such as hypoxia, acidosis, H2O2-rich conditions and condens...

    Authors: Juanjuan Li, Chunai Gong, Xinlu Chen, Huanhuan Guo, Zongguang Tai, Nan Ding, Shen Gao and Yuan Gao
    Citation: Journal of Nanobiotechnology 2023 21:123
  20. How to achieve delicate regulation of enzyme activity and empower it with more roles is the peak in the field of enzyme catalysis research. Traditional proteases or novel nano-enzymes are unable to achieve sti...

    Authors: Lu Zhang, Haiping Wu, Yirong Chen, Songzhi Zhang, Mingxuan Song, Changjin Liu, Jia Li, Wei Cheng and Shijia Ding
    Citation: Journal of Nanobiotechnology 2023 21:122
  21. Liver fibrosis could be the last hope for treating liver cancer and remodeling of the hepatic microenvironment has emerged as a strategy to promote the ablation of liver fibrosis. In recent years, especially w...

    Authors: Xingtao Zhao, Felix Kwame Amevor, Xinyan Xue, Cheng Wang, Zhifu Cui, Shu Dai, Cheng Peng and Yunxia Li
    Citation: Journal of Nanobiotechnology 2023 21:121

    The Correction to this article has been published in Journal of Nanobiotechnology 2023 21:152

  22. Antigen self-assembly nanovaccines advance the minimalist design of therapeutic cancer vaccines, but the issue of inefficient cross-presentation has not yet been fully addressed. Herein, we report a unique app...

    Authors: Runping Su, Jingjing Gu, Juanjuan Sun, Jie Zang, Yuge Zhao, Tingting Zhang, Yingna Chen, Gaowei Chong, Weimin Yin, Xiao Zheng, Bingbing Liu, Li Huang, Shuangrong Ruan, Haiqing Dong, Yan Li and Yongyong Li
    Citation: Journal of Nanobiotechnology 2023 21:120
  23. Sustained release of bioactive BMP2 (bone morphogenetic protein-2) is important for bone regeneration, while the intrinsic short half-life of BMP2 at protein level cannot meet the clinical need. In this study,...

    Authors: Zhujun Yang, Xuejian Li, Xueqi Gan, Mengying Wei, Chunbao Wang, Guodong Yang, Yimin Zhao, Zhuoli Zhu and Zhongshan Wang
    Citation: Journal of Nanobiotechnology 2023 21:119
  24. Glyco-quantum dots (glyco-QDs) have attracted significant interest in bioimaging applications, notably in cancer imaging, because they effectively combine the glycocluster effect with the exceptional optical p...

    Authors: Xiaolin Guan, Liyuan Zhang, Shoujun Lai, Jiaming Zhang, Jingyu Wei, Kang Wang, Wentao Zhang, Chenghao Li, Jinhui Tong and Ziqiang Lei
    Citation: Journal of Nanobiotechnology 2023 21:118
  25. In a significant proportion of cancers, point mutations of TP53 gene occur within the DNA-binding domain, resulting in an abundance of mutant p53 proteins (mutp53) within cells, which possess tumor-promoting p...

    Authors: Hao Zhang, Wang Zhang, Bochuan Hu, Xiaohua Qin, Tianxiang Yi, Yayi Ye, Xiaowan Huang, Yang Song, Zhenyu Yang, Jieying Qian and Yunjiao Zhang
    Citation: Journal of Nanobiotechnology 2023 21:117
  26. Biofilm-related diseases are a group of diseases that tolerate antimicrobial chemotherapies and therefore are refractory to treatment. Periodontitis, a non-device chronic biofilm disease induced by dental plaq...

    Authors: Haotian Luo, Danying Chen, Ruoyu Li, Runze Li, Yungshan Teng, Yang Cao, Xuenong Zou, Weicai Wang and Chen Zhou
    Citation: Journal of Nanobiotechnology 2023 21:116
  27. The lack of predictive models that mimic the blood–brain barrier (BBB) hinders the development of effective drugs for neurodegenerative diseases. Animal models behave differently from humans, are expensive and...

    Authors: Sujey Palma-Florez, Adrián López-Canosa, Francisco Moralez-Zavala, Oscar Castaño, Marcelo J. Kogan, Josep Samitier, Anna Lagunas and Mònica Mir
    Citation: Journal of Nanobiotechnology 2023 21:115
  28. The past few years have witnessed a significant increase in research related to plant-derived extracellular vesicles (PDEVs) in biological and medical applications. Using biochemical technologies, multiple ind...

    Authors: Zhijie Xu, Yuzhen Xu, Kui Zhang, Yuanhong Liu, Qiuju Liang, Abhimanyu Thakur, Wei Liu and Yuanliang Yan
    Citation: Journal of Nanobiotechnology 2023 21:114
  29. Hypertrophic scars (HS) affect millions of people each year and require better treatment strategies. Bacterial extracellular vesicles (EVs) are advantaged by low cost and high yield which was commonly used in ...

    Authors: Fu Han, Kejia Wang, Kuo Shen, Jing Wang, Shichao Han, Dahai Hu and Gaofeng Wu
    Citation: Journal of Nanobiotechnology 2023 21:113
  30. Residual lesions in the tumor bed have been a challenge for conventional white-light breast-conserving surgery. Meanwhile, lung micro-metastasis also requires improved detection methods. Intraoperative accurat...

    Authors: Zhongquan Cheng, Yushen Jin, Jiaqian Li, Guangyuan Shi, Leyi Yu, Bing Shao, Jie Tian, Yang Du and Zhu Yuan
    Citation: Journal of Nanobiotechnology 2023 21:112
  31. Although exosome therapy has been recognized as a promising strategy in the treatment of rheumatoid arthritis (RA), sustained modulation on RA specific pathogenesis and desirable protective effects for attenua...

    Authors: Ke Rui, Xiaoxuan Tang, Ziwei Shen, Chao Jiang, Qiugang Zhu, Shiyi Liu, Nan Che, Jie Tian, Jue Ling and Yumin Yang
    Citation: Journal of Nanobiotechnology 2023 21:111
  32. With increased diabetes incidence, diabetic wound healing is one of the most common diabetes complications and is characterized by easy infection, chronic inflammation, and reduced vascularization. To address ...

    Authors: Hao Yu, Yijia Li, Yining Pan, Hongning Wang, Wei Wang, Xiaobin Ren, Hang Yuan, Ziru Lv, Yijia Zuo, Zhirong Liu, Wei Lin and Qingqing Yao
    Citation: Journal of Nanobiotechnology 2023 21:110
  33. Ferroptosis plays a critical role in ischemic stroke, and anti-ferroptosis strategies were regarded as potentially effective measures. Based on ferroptosis-related mechanisms, this study aims to design and pre...

    Authors: Yong Wang, Huicong Niu, Luyu Li, Jing Han, Zhuohang Liu, Min Chu, Xianyi Sha and Jing Zhao
    Citation: Journal of Nanobiotechnology 2023 21:109
  34. Various bacteria and archaea, including halophilic archaeon Halobacterium sp. NRC-1 produce gas vesicle nanoparticles (GVNPs), a unique class of stable, air-filled intracellular proteinaceous nanostructures. GVNP...

    Authors: Ram Karan, Dominik Renn, Shuho Nozue, Lingyun Zhao, Satoshi Habuchi, Thorsten Allers and Magnus Rueping
    Citation: Journal of Nanobiotechnology 2023 21:108
  35. Due to the excellent biocompatible physicochemical performance, luminogens with aggregation-induced emission (AIEgens) characteristics have played a significant role in biomedical fluorescence imaging recently...

    Authors: Yibin Zhang, Miaozhuang Fan, Zhourui Xu, Yihang Jiang, Huijun Ding, Zhengzheng Li, Kaixin Shu, Mingyan Zhao, Gang Feng, Ken-Tye Yong, Biqin Dong, Wei Zhu and Gaixia Xu
    Citation: Journal of Nanobiotechnology 2023 21:107
  36. Owing to its diverse heterogeneity, aggressive nature, enormous metastatic potential, and high remission rate, the breast cancer (BC) is among the most prevalent types of cancer associated with high mortality....

    Authors: Jinku Zhang, Jirui Sun, Chong Li, Haizhi Qiao and Zahid Hussain
    Citation: Journal of Nanobiotechnology 2023 21:106
  37. Rheumatoid arthritis (RA) is a systemic immune disease characterized by synovial inflammation. Patients with RA commonly experience significant damage to their hand and foot joints, which can lead to joint def...

    Authors: Xiao-Kai Chi, Xiao-Ling Xu, Bang-Yao Chen, Jin Su and Yong-Zhong Du
    Citation: Journal of Nanobiotechnology 2023 21:105
  38. Non-small cell lung cancer (NSCLC) is the most common pathological type of LC and ranks as the leading cause of cancer deaths. Circulating exosomes have emerged as a valuable biomarker for the diagnosis of NSC...

    Authors: Fanyu Meng, Wenjun Yu, Minjia Niu, Xiaoting Tian, Yayou Miao, Xvelian Li, Yan Zhou, Lifang Ma, Xiao Zhang, Kun Qian, Yongchun Yu, Jiayi Wang and Lin Huang
    Citation: Journal of Nanobiotechnology 2023 21:104
  39. Osteosarcoma, the most common malignant tumor of the bone, seriously influences people’s lives and increases their economic burden. Conventional chemotherapy drugs achieve limited therapeutic effects owing to ...

    Authors: Pengzhi Shi, Zhangrong Cheng, Kangcheng Zhao, Yuhang Chen, Anran Zhang, Weikang Gan and Yukun Zhang
    Citation: Journal of Nanobiotechnology 2023 21:103
  40. Disruption of the cell cycle is among the most effective approach to increase tumour cells’ radio-sensitivity. However, the presence of dose-limiting side effects hampers the clinical use of tyrosine kinase in...

    Authors: Pouya Dehghankelishadi, Parisa Badiee, Michelle F. Maritz, Nicole Dmochowska and Benjamin Thierry
    Citation: Journal of Nanobiotechnology 2023 21:102
  41. Tumor microenvironment (TME) plays an important role in tumor progression, metastasis and therapy resistance. Remodeling the TME has recently been deemed an attractive tumor therapeutic strategy. Due to its co...

    Authors: Yinhui Hang, Yanfang Liu, Zhaogang Teng, Xiongfeng Cao and Haitao Zhu
    Citation: Journal of Nanobiotechnology 2023 21:101
  42. Cathepsin B, a cysteine protease, is considered a potential biomarker for early diagnosis of cancer and inflammatory bowel diseases. Therefore, more feasible and effective diagnostic method may be beneficial f...

    Authors: Ji Hong Kim, Jae Hwan Shin, Bumjun Park, Chae Hwan Cho, Yun Suk Huh, Chang-Hyung Choi and Jong Pil Park
    Citation: Journal of Nanobiotechnology 2023 21:100
  43. Excessive reactive oxygen species (ROS) in nucleus pulposus cells (NPCs) promote extracellular matrix (ECM) degradation and cellular inflammatory responses by activating a variety of cellular pathways, ultimat...

    Authors: Hao Yu, Yun Teng, Jun Ge, Ming Yang, Haifeng Xie, Tianyi Wu, Qi Yan, Mengting Jia, Qing Zhu, Yanping Shen, Lianxue Zhang and Jun Zou
    Citation: Journal of Nanobiotechnology 2023 21:99
  44. Bone regeneration is a complex procedure that involves an interaction between osteogenesis and inflammation. Macrophages in the microenvironment are instrumental in bone metabolism. Amount evidence have reveal...

    Authors: Yuxuan Chen, Yuanhao Wu, Linlin Guo, Shijie Yuan, Jiaming Sun, Kangcheng Zhao, Jiecong Wang and Ran An
    Citation: Journal of Nanobiotechnology 2023 21:98
  45. Assessing the antimicrobial activity of engineered nanomaterials (ENMs), especially in realistic scenarios, is of great significance for both basic research and applications. Multiple analytical methods are av...

    Authors: Xuzhi Zhang, Xiangyi Hou, Liangyu Ma, Yaqi Shi, Dahai Zhang and Keming Qu
    Citation: Journal of Nanobiotechnology 2023 21:97
  46. Clostridium perfringens ε-toxin (ETX) is the main toxin leading to enterotoxemia of sheep and goats and is classified as a potential biological weapon. In addition, no effective treatment drug is currently availa...

    Authors: Jinglin Xu, Dongxue Li, Lin Kang, Tingting Liu, Jing Huang, Jiaxin Li, Jing Lv, Jing Wang, Shan Gao, Yanwei Li, Bing Yuan, Baohua Zhao, Jinglin Wang and Wenwen Xin
    Citation: Journal of Nanobiotechnology 2023 21:95
  47. Currently, the etiology of idiopathic short stature (ISS) is still unclear. The poor understanding of the molecular mechanisms of ISS has largely restricted this strategy towards safe and effective clinical th...

    Authors: Xijuan Liu, Jinghong Yuan, Zhiwen Wu, Junqiu Zhang, Yunfeng Shen and Jingyu Jia
    Citation: Journal of Nanobiotechnology 2023 21:94

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