Figure 3From: A signal amplification assay for HSV type 1 viral DNA detection using nanoparticles and direct acoustic profilingPredicted change in sensor frequency (expressed as parts per million of the fundamental sensor frequency per particle bound) as a function of capture layer shear stiffness for 60, 40 and 15 nm gold particles for the 16.5 MHz sensor used in the experimental work. Note the rapid loss of sensitivity as the stiffness drops below 1 × 106 Pa.Back to article page