Fig. 4

In vivo pulmonary distribution. a The pulmonary distribution of ICAM/DEX/NLCs, IgG/DEX/NLCs, ICAM/DEX/ODA-NLCs and IgG/DEX/NLCs in healthy mice and LPS-induced ALI mice after 24 h drug administration. b The semi-quantitative fluorescence intensity in the lungs, expressed as the average fluorescence intensity (avg signal/counts). ^###p < 0.01 indicated the pulmonary fluorescence intensity of IgG/DEX/NLCs treated group compared with that of ICAM/DEX/NLCs treated group in healthy mice. *p < 0.05, **p < 0.01 indicated the pulmonary fluorescence intensity of corresponding groups compared with that of ICAM/DEX/NLCs treated group in ALI mice