Fig. 7

P/LLL/CTX/ICG nanoconjugate for NIR-guided resection of brain tumor. a Composition of P/LLL/CTX/ICG and its injection into murine model of brain tumor. b Ex vivo fluorescence microscopy showing extravasation of P/LLL/CTX/ICG across BBB and intense distribution outside blood capillary and next to nuclei in tumor cells. c Biodistribution of P/LLL/CTX/ICG and d Real time NIR-imaging and surgical resection of GBM, 4 h after IV injection into mouse tail vein. Reprinted from ref. [110], with permission from Elsevier, Copyright 2019