Fig. 1
From: Delivery of engineered extracellular vesicles with miR-29b editing system for muscle atrophy therapy
Design of engineered extracellular vesicles delivering miR-29b editing system. a Schematic diagram of engineered extracellular vesicles. b The flow chart used to synthesize engineered extracellular vesicles. c Western blot analysis of Cas9, V-SVG, CD63, CD9, TSG101, GAPDH, TOM20, Calnexin and APOA1 protein in engineered extracellular vesicles and C2C12 cells. d Fluorescent nanoparticle tracking analysis (FNTA) to determine the size distribution of engineered extracellular vesicles. e Transmission electron microscopic (TEM) analysis of purified engineered extracellular vesicles’ structure and size (scale bar: 100 nm)