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Scheme 1 | Journal of Nanobiotechnology

Scheme 1

From: Biocompatible exosome-modified fibrin gel accelerates the recovery of spinal cord injury by VGF-mediated oligodendrogenesis

Scheme 1

Sequential scheme of the experiments performed. Rat BMSC-derived exosomes were extracted and then encapsulated in fibrin gel to form Gel-Exo. The repair effects of Gel-Exo on SCI mice were investigated, and the underlying mechanisms were studied using RNA-seq analysis. VGF and VGF-mediated oligodendrogenesis were identified, then VGF lentivirus was employed to overexpress VGF in the lesion site of SCI, which accelerated the recovery of SCI. The figure was created with BioRender.com

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Journal of Nanobiotechnology

ISSN: 1477-3155

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