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Correction: A non‑invasive nanoparticles for multimodal imaging of ischemic myocardium in rats

The Original Article was published on 22 March 2021

Correction: J Nanobiotechnol (2021) 19:82

After the publication of the original article [1], the authors have identified mistakes in Fig. 2d, Fig. 5b, and Additional file 1: Figure S7. The revised figures are shown in this correction. All authors sincerely apologize for these errors.

Fig. 2
figure 2

The safety profile of NPs. a Morphology of normal H9C2 cells and co-incubation with IMTP-Fe3O4-PFH NPs (scale bar: 100 μm). b Cell viability of H9C2 cells after co-incubation with different concentrations of IMTP-Fe3O4-PFH NPs. c Blood biochemical indexes analysis of SD rats from the control group and the experimental groups at 1, 3, 7, and 14 d post intravenous injection of IMTP-Fe3O4-PFH NPs. d HE staining of major organs from the control group and 14 d experimental group after 14 d of intravenous administration with IMTP-Fe3O4-PFH NPs (scale bar: 100 μm)

Fig. 5
figure 5

Phase transition and US imaging in vitro. a Light microscope images of phase transformation induced by LIFU (scale bar = 10 μm). b The ultrasound imaging (left: B-Mode, right: CEUS) of IMTP-Fe3O4-PFH NPs with time- and intensity-dependent ADV. Quantitative analysis of the echo intensity of NPs after LIFU irradiation at different intensities and time in B-mode (c) and CEUS-mode (d)


  1. Chen X, Zhang Y, Zhang H, Zhang L, Liu L, Cao Y, Ran H, Tian J. A non-invasive nanoparticles for multimodal imaging of ischemic myocardium in rats. J Nanobiotechnol. 2021;19(1):82.

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Correspondence to Jie Tian.

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Supplementary Information

Additional file 1: Figure S7.

ADV and US imaging of IMTP-Fe3O4 NPs at different intensities of LIFU irritation and different time in vitro. Echo intensity did not change in all cases.

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Chen, X., Zhang, Y., Zhang, H. et al. Correction: A non‑invasive nanoparticles for multimodal imaging of ischemic myocardium in rats. J Nanobiotechnol 20, 382 (2022).

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