Table 1 List of clinical trials of polymeric nanomedicines for the treatment of liver diseases (clinicaltrials.gov)
From: Polymeric nanomedicines for the treatment of hepatic diseases
Cause | Name | Payload name | Carrier | Year of starting/completion | Study phase | No. of patients | Status | Clinical trials identifier |
|---|---|---|---|---|---|---|---|---|
HCC | Genexol-PM | Paclitaxel | Polymeric micelle | 2016/2021 | 2 | 5 | Terminated | NCT03008512 |
HCC | Doxorubicin | Doxorubicin | Polymer microspheres | 2010/2012 | 1/2 | 24 | Completed | NCT01116635 |
HCC | Doxorubicin | Doxorubicin | Polymer microsphere | 2016/2019 | – | 100 | Recruiting | NCT02743065 |
HCC | PK2 | Doxorubicin | HPMA drug conjugate | – | 2 | – | Completed | [19] |
HCC | DHAD-PBCA-NPs | Mitoxantrone | Polybutylcyanacrylate nanoparticles | –/2009 | 2 | 108 | Completed | [20] |
HCC | Lipotecan | TLC388 (Camptothecin derivate) | Polymeric micelle | 2014/2015 | 2 | 29 | Terminated | NCT02267213 |
HCC | Doxorubicin Transdrug | Doxorubicin | Poly(isohexyl cyanoacrylate) nanoparticle | 2012/2019 | 3 | 397 | Completed | NCT01655693 |
NAFLD | Nanocurcumin | Curcumin | Polymeric nanoparticle | 2016/2017 | – | 84 | Completed | [21] |