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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Magnetic separation and concentration of Aβ 1–42 molecules dispersed at the threshold concentration for Alzheimer’s disease diagnosis in clinically-relevant volumes of sample

Fig. 8

Quantitative analysis of the molecular binding between Αβ1 − 42 and KLVFF-functionalized MNPs as a function of the numerical ratio Αβ1 − 42: MNP (green histograms). As a control it is shown the binding ratio between bare MNPs (grey histograms). Aβ1 − 42 concentrations for the experiments with 1:1 and 1:3 ratios – 600 pg/ml and 200 pg/ml, respectively – are usually found in clinical samples. 600 pg/ml (1:1 ratio in the figure) in particular is considered the cut-off value for early AD diagnosis [39, 40]

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Journal of Nanobiotechnology

ISSN: 1477-3155

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