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Table 2 Experimental data on binding rate between non-functionalized MNPs and Aβ1−42 molecules when they are mixed in 1:1 numerical ratio. The experimental procedure behind is the same as for the data in Table 1. No decrease in the Aβ1−42 concentrations has been measured

From: Magnetic separation and concentration of Aβ 1–42 molecules dispersed at the threshold concentration for Alzheimer’s disease diagnosis in clinically-relevant volumes of sample

Aβ concentration

(ng/ml)

MNP

concentration

(µg/ml)

Numerical ratio

(Aβ/MNP)

Dilution

factor

Initial Aβ concentration

- \(\varvec{A}\varvec{\beta }0\) -

(pg/ml)

*after dilution

Final Aβ concentration

-\(\varvec{A}\varvec{\beta }\varvec{f}\) -

(pg/ml)

Binding rate (%)

\(1-\frac{\varvec{A}\varvec{\beta }\varvec{f}}{\varvec{A}\varvec{\beta }0}\)

REAL CONCENTRATION

RAW EXPERIMENTAL RESULTS

 

1

5

1:1

1/5

366

384

0

1

5

1:1

1/5

338

365

0

  1. Binding ratio average: 0%