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  1. Nanoparticles have now long demonstrated capabilities that make them attractive to use in biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or metallic nanoparticles (contra...

    Authors: Enrica Soprano, Ester Polo, Beatriz Pelaz and Pablo del Pino
    Citation: Journal of Nanobiotechnology 2022 20:538
  2. Surface-enhanced Raman scattering (SERS) is a very promising tool for the direct detection of biomarkers for the diagnosis of i.e., cancer and pathogens. Yet, current SERS strategies are hampered by non-specif...

    Authors: Kaisong Yuan, Beatriz Jurado-Sánchez and Alberto Escarpa
    Citation: Journal of Nanobiotechnology 2022 20:537
  3. Despite significant progress in synthetic polymer chemistry and in control over tuning the structures and morphologies of nanoparticles, studies on morphologic design of nanomaterials for the purpose of optimi...

    Authors: Fatma Al-Zahraa Sayed, Noura G. Eissa, Yidan Shen, David A. Hunstad, Karen L. Wooley and Mahmoud Elsabahy
    Citation: Journal of Nanobiotechnology 2022 20:536
  4. Magnetic nanoparticles are widely used in biomedicine for MRI imaging and anemia treatment. The aging of these nanomaterials in vivo may lead to gradual diminishing of their contrast properties and inducing to...

    Authors: Alexey V. Yaremenko, Ivan V. Zelepukin, Ilya N. Ivanov, Roman O. Melikov, Nadezhda A. Pechnikova, Dzhuliia Sh. Dzhalilova, Aziz B. Mirkasymov, Vera A. Bragina, Maxim P. Nikitin, Sergey M. Deyev and Petr I. Nikitin
    Citation: Journal of Nanobiotechnology 2022 20:535
  5. Generated by the immune system post-infection or through vaccination, the effectiveness of antibodies against emerging SARS-CoV-2 variants is crucial for protecting individuals from the COVID-19 pandemic. Here...

    Authors: Ruibin Hu, Yang Yang, Ying Liu, Tao Liao, Yiyi Liu, Jiahu Tang, Guanghui Wang, Guoxin Wang, Yongye Liang, Jing Yuan and Bo Zhang
    Citation: Journal of Nanobiotechnology 2022 20:533
  6. The increasing prevalence of antibiotic resistance by Pseudomonas aeruginosa (PA) raises an urgent need for an effective vaccine. The outer membrane proteins of PA, especially those that are upregulated during in...

    Authors: Chen Gao, Yin Chen, Xin Cheng, Yi Zhang, Yueyue Zhang, Ying Wang, Zhiyuan Cui, Yaling Liao, Ping Luo, Weihui Wu, Cheng Wang, Hao Zeng, Quanming Zou and Jiang Gu
    Citation: Journal of Nanobiotechnology 2022 20:532
  7. Acute myocardial infarction (AMI) is usually caused by coronary thrombosis. However, the short half-life, lack of targetability and inevitable ischemia/reperfusion injury secondary to revascularization, which ...

    Authors: Xiaoyu Guo, Ting Hong, Jie Zang, Rongjiao Shao, Xumin Hou, Kai Wang, Weizhuo Liu, Fan Su and Bin He
    Citation: Journal of Nanobiotechnology 2022 20:531
  8. Extracellular Vesicles (EVs) are sub-micrometer lipid-bound particles released by most cell types. They are considered a promising source of cancer biomarkers for liquid biopsy and personalized medicine due to...

    Authors: Maria Eleonora Temperini, Flavio Di Giacinto, Sabrina Romanò, Riccardo Di Santo, Alberto Augello, Raffaella Polito, Leonetta Baldassarre, Valeria Giliberti, Massimiliano Papi, Umberto Basile, Benedetta Niccolini, Ewa K. Krasnowska, Annalucia Serafino, Marco De Spirito, Alessandra Di Gaspare, Michele Ortolani…
    Citation: Journal of Nanobiotechnology 2022 20:530
  9. Neuroinflammation is an important cause of poor prognosis in patients with spinal cord injury. pyroptosis is a new type of inflammatory cell death. Treg cells has been shown to play an anti-inflammatory role i...

    Authors: Wu Xiong, Cong Li, Guang Kong, Qiang Zeng, Siming Wang, Guoyong Yin, Jun Gu and Jin Fan
    Citation: Journal of Nanobiotechnology 2022 20:529
  10. Through the self-assembled strategy to improve the clinical efficacy of the existing drugs is the focus of current research. Herbal formula granule is a kind of modern dosage form of traditional Chinese medici...

    Authors: Xuemei Huang, Xiaojing Liu, Xiaoyu Lin, Zhihua Yuan, Yaozhi Zhang, Zhijia Wang, Wenmin Pi, Haoqiang Zhao, Haimin Lei and Penglong Wang
    Citation: Journal of Nanobiotechnology 2022 20:527
  11. Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by immune dysregulation, pruritus, and abnormal epidermal barrier function. Compared with conventional mesenchymal stem cell (MSC), ...

    Authors: Jimin Kim, Seul Ki Lee, Minyoung Jung, Seon-Yeong Jeong, Haedeun You, Ji-Yeon Won, Sang-Deok Han, Hye Jin Cho, Somi Park, Joonghoon Park, Tae Min Kim and Soo Kim
    Citation: Journal of Nanobiotechnology 2022 20:526
  12. Glioblastoma (GBM) is the most aggressive brain tumor, which owns the characteristics of high recurrence, low survival rate and poor prognosis because of the existence of blood brain barrier (BBB) and complica...

    Authors: Pengxuan Zhao, Yu Tian, Yongping Lu, Jun Zhang, Anyu Tao, Guangya Xiang and Yani Liu
    Citation: Journal of Nanobiotechnology 2022 20:525
  13. Excessive extracellular matrix (ECM) deposition in pancreatic ductal adenocarcinoma (PDAC) severely limits therapeutic drug penetration into tumors and is associated with poor prognosis. Collagen is the most a...

    Authors: Xiao-Yan Yang, Jin-Guo Zhang, Qiao-Mei Zhou, Jie-Ni Yu, Yuan-Fei Lu, Xiao-Jie Wang, Jia-Ping Zhou, Xin-Fa Ding, Yong-Zhong Du and Ri-Sheng Yu
    Citation: Journal of Nanobiotechnology 2022 20:524
  14. Selenium (Se) maintains soil-plant homeostasis in the rhizosphere and regulates signaling molecules to mitigate cadmium (Cd) toxicity. However, there has been no systematic investigation of the effects of nano...

    Authors: Dong Li, Chunran Zhou, Jia-Qi Li, Qinyong Dong, Peijuan Miao, Yongxi Lin, Haiyan Cheng, Yuwei Wang, Luna Luo and Canping Pan
    Citation: Journal of Nanobiotechnology 2022 20:523
  15. Critical-sized bone defects are always difficult to treat, and they are associated with a significant burden of disease in clinical practice. In recent decades, due to the fast development of biomaterials and ...

    Authors: Jinfeng Huang, Ana Cláudia Santos, Quanchang Tan, Hao Bai, Xiaofan Hu, Narsimha Mamidi and Zixiang Wu
    Citation: Journal of Nanobiotechnology 2022 20:522
  16. Antitumor T cell immunotherapy as a novel cancer therapeutic strategy has shown enormous promise. However, the tumor microenvironment (TME) is characterized by the low immunogenicity, hypoxia, and immunosuppre...

    Authors: Lipeng Zhu, Junnan Li, Ziang Guo, Hang Fai Kwok and Qi Zhao
    Citation: Journal of Nanobiotechnology 2022 20:521
  17. Dengue, yellow fever, Chinkungunya, Zika virus, and West Nile fever have infected millions and killed a considerable number of humans since their emergence. These arboviruses are transmitted by mosquito bites ...

    Authors: Daniele Carvalho Abrantes, Carolina Barbara Rogerio, Estefânia Vangelie Ramos Campos, Tais Germano-Costa, Aryane Alves Vigato, Ian Pompermeyer Machado, Anderson Ferreira Sepulveda, Renata Lima, Daniele Ribeiro de Araujo and Leonardo Fernandes Fraceto
    Citation: Journal of Nanobiotechnology 2022 20:520
  18. Proliferative vitreoretinopathy (PVR) is a blind-causing disease initiated by the activation of retinal pigmented epithelium (RPE) primarily induced by TGF-β families. Migrasome is a recently discovered type o...

    Authors: Liangjing Wu, Shuai Yang, Hui Li, Yao Zhang, Le Feng, Conghui Zhang, Jiayi Wei, Xunyi Gu, Guotong Xu, Zhaoyang Wang and Fang Wang
    Citation: Journal of Nanobiotechnology 2022 20:519
  19. Nanoparticle (NP) delivery to solid tumors remains an actively studied field, where several recent studies have shed new insights into the underlying mechanisms and the still overall poor efficacy. In the pres...

    Authors: Mukaddes Izci, Christy Maksoudian, Filipa Gonçalves, Lucia Aversa, Robbe Salembier, Ara Sargsian, Irati Pérez Gilabert, Tianjiao Chu, Carla Rios Luci, Eduardo Bolea-Fernandez, David Nittner, Frank Vanhaecke, Bella B. Manshian and Stefaan J. Soenen
    Citation: Journal of Nanobiotechnology 2022 20:518
  20. Oxidative stress damage to renal epithelial cells is the main pathological factor of calcium oxalate calculi formation. The development of medicine that could alleviate oxidative damage has become the key to t...

    Authors: Jiwang Deng, Bangxian Yu, Zhenglin Chang, Sicheng Wu, Guanlin Li, Wenzhe Chen, Shujue Li, Xiaolu Duan, Wenqi Wu, Xinyuan Sun, Guohua Zeng and Hongxing Liu
    Citation: Journal of Nanobiotechnology 2022 20:516
  21. Nanomaterials are widely used as pesticide adjuvants to increase pesticide efficiency and minimize environmental pollution. But it is increasingly recognized that nanocarrier is a double-edged sword, as nanopa...

    Authors: Shuo Yan, Na Li, Yuankang Guo, Yao Chen, Chendong Ji, Meizhen Yin, Jie Shen and Junzheng Zhang
    Citation: Journal of Nanobiotechnology 2022 20:515
  22. The prevalence of viral infectious diseases has become a serious threat to public safety, economic and social development. Vaccines have been served as the most effective platform to prevent virus transmission...

    Authors: Jian Huo, Angke Zhang, Shuqi Wang, Hanghang Cheng, Daopeng Fan, Ran Huang, Yanan Wang, Bo Wan, Gaiping Zhang and Hua He
    Citation: Journal of Nanobiotechnology 2022 20:514
  23. The discovery of a potent photosensitizer with desirable immunogenic cell death (ICD) ability can prominently enhance antitumor immunity in photodynamic therapy (PDT). However, majority of commercially-availab...

    Authors: Hong Wang, Guoxin Jing, Jintong Niu, Li Yang, Youyuan Li, Yi Gao, Huichao Wang, Xiaorong Xu, Yechang Qian and Shilong Wang
    Citation: Journal of Nanobiotechnology 2022 20:513
  24. Reversing the immunosuppressive tumor microenvironment (TME) in the tumor is widely deemed to be an effective strategy to improve immune therapy. In particular, the redox balance in TME needs to be well contro...

    Authors: Zhiheng Zeng, Changhui Fu, Xiaohan Sun, Meng Niu, Xiangling Ren, Longfei Tan, Qiong Wu, Zhongbing Huang and Xianwei Meng
    Citation: Journal of Nanobiotechnology 2022 20:512
  25. Inherited Retinal Diseases (IRDs) are considered one of the leading causes of blindness worldwide. However, the majority of them still lack a safe and effective treatment due to their complexity and genetic he...

    Authors: Yueh Chien, Yu-Jer Hsiao, Shih-Jie Chou, Ting-Yi Lin, Aliaksandr A. Yarmishyn, Wei-Yi Lai, Meng-Shiue Lee, Yi-Ying Lin, Tzu-Wei Lin, De-Kuang Hwang, Tai-Chi Lin, Shih-Hwa Chiou, Shih-Jen Chen and Yi-Ping Yang
    Citation: Journal of Nanobiotechnology 2022 20:511
  26. Nanotopographical cues of bone implant surface has direct influences on various cell types during the establishment of osseointegration, a prerequisite of implant bear-loading. Given the important roles of mon...

    Authors: Yide He, Yuanxue Gao, Qianli Ma, Xige Zhang, Yumei Zhang and Wen Song
    Citation: Journal of Nanobiotechnology 2022 20:510
  27. Norcantharidin (NCTD) is a demethylated derivative of cantharidin (CTD), the main anticancer active ingredient isolated from traditional Chinese medicine Mylabris. NCTD has been approved by the State Food and ...

    Authors: Bing-Tao Zhai, Jing Sun, Ya-Jun Shi, Xiao-Fei Zhang, Jun-Bo Zou, Jiang-Xue Cheng, Yu Fan, Dong-Yan Guo and Huan Tian
    Citation: Journal of Nanobiotechnology 2022 20:509
  28. Introducing oxygen-vacancy into the surface of the non-enzymatic sensor is supposed to be an effective way to improve inherently low catalytic activity and specificity of non-enzymatic sensors. In this work, C...

    Authors: Chen Zhao, Xiaoying Tang, Jinge Zhao, Jie Cao, Zhenqi Jiang and Jieling Qin
    Citation: Journal of Nanobiotechnology 2022 20:507
  29. Macrophages participate in many links in the pathological process of atherosclerosis (AS) and the regulation of influence of macrophages at the molecular level might be a new avenue for AS treatment. For this ...

    Authors: Xuan Sha, Yue Dai, Lijuan Chong, Min Wei, Mengyuan Xing, Chun Zhang and Jingjing Li
    Citation: Journal of Nanobiotechnology 2022 20:506
  30. Acute kidney injury (AKI) is one of the most common severe complications among hospitalized patients. In the absence of specific drugs to treat AKI, hemodialysis remains the primary clinical treatment for AKI ...

    Authors: Yuanpeng Nie, Liying Wang, Xinru You, Xiaohua Wang, Jun Wu and Zhihua Zheng
    Citation: Journal of Nanobiotechnology 2022 20:505
  31. Cisplatin (CDDP) is a well-known platinum-based drug used in the treatment of various malignancies. However, the widespread side effects that this drug leaves on normal tissues make its use limited. Since cisp...

    Authors: Maryam Davoudi, Yasaman Jadidi, Kiana Moayedi, Vida Farrokhi and Reza Afrisham
    Citation: Journal of Nanobiotechnology 2022 20:504
  32. The profiling of small extracellular vesicle-associated microRNAs (sEV-miRNAs) plays a vital role in cancer diagnosis and monitoring. However, detecting sEV-miRNAs with low expression in clinical samples remai...

    Authors: Ye Zhang, Wenbin Li, Tingting Ji, Shihua Luo, Jiuxiang Qiu, Bo Situ, Bo Li, Xiaohe Zhang, Tiange Zhang, Wen Wang, Yunju Xiao, Lei Zheng and Xiaohui Yan
    Citation: Journal of Nanobiotechnology 2022 20:503
  33. Dental caries is the major biofilm-mediated oral disease in the world. The main treatment to restore caries lesions consists of the use of adhesive resin composites due to their good properties. However, the p...

    Authors: Marta López-Ruiz, Francisco Navas, Paloma Fernández-García, Samuel Martínez-Erro, Mª Victoria Fuentes, Isabel Giráldez, Laura Ceballos, Carmen Mª Ferrer-Luque, Matilde Ruiz-Linares, Victoria Morales, Raúl Sanz and Rafael A. García-Muñoz
    Citation: Journal of Nanobiotechnology 2022 20:502
  34. Recent efforts in designing nanomaterials to deliver potential therapeutics to the targeted site are overwhelming and palpable. Engineering nanomaterials to deliver biological molecules to exert desirable phys...

    Authors: Ashish Ranjan Sharma, Yeon-Hee Lee, Altanzul Bat-Ulzii, Manojit Bhattacharya, Chiranjib Chakraborty and Sang-Soo Lee
    Citation: Journal of Nanobiotechnology 2022 20:501
  35. As one kind of aggressive cancer, triple-negative breast cancer (TNBC) has become one of the major causes of women mortality worldwide. Recently, combinational chemo-PDT therapy based on nanomaterials has been...

    Authors: Zhihong Zeng, Zhou Wang, Simin Chen, Chang Xiao, Minzhuo Liu, Jie Zhang, Jialong Fan, Yanzhong Zhao and Bin Liu
    Citation: Journal of Nanobiotechnology 2022 20:500
  36. Gene transfection was supposed to be the most promising technology to overcome the vast majority of diseases and it has been popularly reported in clinical applications of gene therapy. In spite of the rapid d...

    Authors: Yongtao Wang, Nana Wang, Yingjun Yang, Yazhou Chen and Zhengguo Zhang
    Citation: Journal of Nanobiotechnology 2022 20:499
  37. The lack of a satisfactory strategy for postoperative pain management significantly impairs the quality of life for many patients. However, existing nanoplatforms cannot provide a longer duration of nerve bloc...

    Authors: Bin Qiao, Xinye Song, Weiyi Zhang, Ming Xu, Bowen Zhuang, Wei Li, Huanling Guo, Wenxin Wu, Guangliang Huang, Minru Zhang, Xiaoyan Xie, Nan Zhang, Yong Luan and Chunyang Zhang
    Citation: Journal of Nanobiotechnology 2022 20:498
  38. Reactive oxygen/nitrogen species (ROS/RNS) are formed during normal cellular metabolism and contribute to its regulation, while many pathological processes are associated with ROS/RNS imbalances. Modern method...

    Authors: Tatiana Abakumova, Alexander Vaneev, Victor Naumenko, Arina Shokhina, Vsevolod Belousov, Arsen Mikaelyan, Kamilla Balysheva, Peter Gorelkin, Alexander Erofeev and Timofei Zatsepin
    Citation: Journal of Nanobiotechnology 2022 20:497
  39. Ocular diseases are increasingly influencing people’s quality of life. Complicated inflammatory mechanisms involved in the pathogenic process of ocular diseases make inflammation-targeting treatment a potentia...

    Authors: Lianfei Fang, Jin Liu, Zeyang Liu and Huifang Zhou
    Citation: Journal of Nanobiotechnology 2022 20:496
  40. Detecting physiological levels of neurotransmitters in biological samples can advance our understanding of brain disorders and lead to improved diagnostics and therapeutics. However, neurotransmitter sensors f...

    Authors: Mafalda Abrantes, Diana Rodrigues, Telma Domingues, Siva S. Nemala, Patricia Monteiro, Jérôme Borme, Pedro Alpuim and Luis Jacinto
    Citation: Journal of Nanobiotechnology 2022 20:495
  41. Carbon monoxide (CO) is an important signaling molecule participating in multiple biological functions. Previous studies have confirmed the valuable roles of CO in cancer therapies. If the CO concentration and...

    Authors: Yiyang Cong, Bo Sun, Jianlun Hu, Xiaoyang Li, Yanan Wang, Jingyi Zhang, Dongzhi Yang, Weifei Lu, Zhi Ding, Xiaofeng Wang and Hao Hong
    Citation: Journal of Nanobiotechnology 2022 20:494
  42. Virus-like particles (VLPs) are supramolecular structures composed of multiple protein subunits and resemble natural virus particles in structure and size, making them highly immunogenic materials for the deve...

    Authors: Ze-Hui Liu, Zhuo-Fan Deng, Ying Lu, Wei-Huan Fang and Fang He
    Citation: Journal of Nanobiotechnology 2022 20:493
  43. Pathogenic microorganism pollution has been a challenging public safety issue, attracting considerable scientific interest. A more problematic aspect of this phenomenon is that planktonic bacteria exacerbate b...

    Authors: Qian Wang, Qingshan Shi, Yulian Li, Shunying Lu and Xiaobao Xie
    Citation: Journal of Nanobiotechnology 2022 20:492
  44. An increasing demand for bioelectronics that interface with living systems has driven the development of materials to resolve mismatches between electronic devices and biological tissues. So far, a variety of ...

    Authors: Daiki Ando, Tetsuhiko F. Teshima, Francisco Zurita, Hu Peng, Kota Ogura, Kenji Kondo, Lennart Weiß, Ayumi Hirano-Iwata, Markus Becherer, Joe Alexander and Bernhard Wolfrum
    Citation: Journal of Nanobiotechnology 2022 20:491
  45. Deficient deposition of X-rays and strong capacity of repairing damage DNA of cancer cells limit the effect of radiation therapy (RT). Herein, we synthesize CsLu2F7 nanoparticles with lactic acid (LA) ligands (Cs...

    Authors: Hu Liu, Han Wang, Dalong Ni and Youjia Xu
    Citation: Journal of Nanobiotechnology 2022 20:490
  46. Circular RNA (circRNA) is a type of stable non-coding RNA that modifies macrophage inflammation by sponging micro RNAs (miRNAs), binding to RNA-binding proteins, and undergoing translation into peptides. Activ...

    Authors: Yuhua Gao, Ningning Mi, Ying Zhang, Xiangchen Li, Weijun Guan and Chunyu Bai
    Citation: Journal of Nanobiotechnology 2022 20:487

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