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  1. The incidence of lung cancer continues to rise worldwide. Because the aggressive metastasis of lung cancer cells is the major drawback of successful therapies, the crucial challenge of modern nanomedicine is t...

    Authors: Monika Ruzycka, Mihaela R. Cimpan, Ivan Rios-Mondragon and Ireneusz P. Grudzinski

    Citation: Journal of Nanobiotechnology 2019 17:71

    Content type: Review

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  2. Copper oxide nanomaterials (CuO NMs) are exploited in many products including inks, cosmetics, textiles, wood preservatives and food contact materials. Their incorporation into these products may enhance oral ...

    Authors: Victor C. Ude, David M. Brown, Vicki Stone and Helinor J. Johnston

    Citation: Journal of Nanobiotechnology 2019 17:70

    Content type: Research

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  3. The major obstacle impeding human immunodeficiency virus-1 (HIV-1) eradication in antiretroviral treatment (ART) treated HIV-1 subjects is the establishment of long-lived latently infected resting CD4+ T cells. D...

    Authors: Ignacio Relaño-Rodríguez, Raquel Juárez-Sánchez, Carolina Pavicic, Eduardo Muñoz and Maria Ángeles Muñoz-Fernández

    Citation: Journal of Nanobiotechnology 2019 17:69

    Content type: Short Communication

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  4. Nanotechnology in medicine has greatly expanded the therapeutic strategy that may be explored for cancer treatment by exploiting the specific tumor microenvironment such as mild acidity, high glutathione (GSH)...

    Authors: Wei Tang, Hongbo Gao, Dalong Ni, QiFeng Wang, Bingxin Gu, Xinhong He and Weijun Peng

    Citation: Journal of Nanobiotechnology 2019 17:68

    Content type: Research

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  5. Immunochromatographic strips (ICSs) are a practical tool commonly used in point-of-care testing (POCT) applications. However, ICSs that are currently available have low sensitivity and require expensive equipm...

    Authors: Qiangqiang Fu, Ze Wu, Jingxia Li, Zengfeng Wu, Hui Zhong, Quanli Yang, Qihui Liu, Zonghua Liu, Lianghe Sheng, Meng Xu, Tingting Li, Zhinan Yin and Yangzhe Wu

    Citation: Journal of Nanobiotechnology 2019 17:67

    Content type: Research

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  6. The wide application of silver nanoparticles (AgNPs) in medicals and daily utensils increases the risk of human exposure. The study on cell and protein changes induced by medical AgNPs (20 nm) and Ag+ gave insigh...

    Authors: Wenxu Fang, Zhenxing Chi, Weiguo Li, Xunuo Zhang and Qiang Zhang

    Citation: Journal of Nanobiotechnology 2019 17:66

    Content type: Research

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  7. It is essential that prophylactic drugs do not interfere with the normal function of the immune system. The use of nanoparticles as vaginal microbicides is a promising prevention strategy against sexually tran...

    Authors: Alba Martín-Moreno, Daniel Sepúlveda-Crespo, Mª Jesús Serramía-Lobera, Ana Judith Perisé-Barrios and Mª Angeles Muñoz-Fernández

    Citation: Journal of Nanobiotechnology 2019 17:65

    Content type: Research

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  8. Age-related macular degeneration (AMD) is a leading cause of severe visual deficits and blindness. Meanwhile, there is convincing evidence implicating oxidative stress, inflammation, and neovascularization in ...

    Authors: Sisi Lai, Yanyan Wei, Quanwu Wu, Kang Zhou, Tuo Liu, Yingfeng Zhang, Ning Jiang, Wen Xiao, Junjie Chen, Qiuhong Liu and Yang Yu

    Citation: Journal of Nanobiotechnology 2019 17:64

    Content type: Research

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  9. Silver ions from silver nanoparticles (AgNP) or AgNPs themselves itself that are ingested from consumer health care products or indirectly from absorbed food contact material can interact with the gastrointest...

    Authors: Sarah E. Orr, Kuppan Gokulan, Mary Boudreau, Carl E. Cerniglia and Sangeeta Khare

    Citation: Journal of Nanobiotechnology 2019 17:63

    Content type: Research

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  10. Human hematopoietic progenitor cells (HPCs) are important for cell therapy in cancer and tissue regeneration. In vitro studies have shown a transient association of 40 nm polystyrene nanoparticles (PS NPs) wit...

    Authors: Bart Wathiong, Sarah Deville, An Jacobs, Nick Smisdom, Pascal Gervois, Ivo Lambrichts, Marcel Ameloot, Jef Hooyberghs and Inge Nelissen

    Citation: Journal of Nanobiotechnology 2019 17:62

    Content type: Research

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  11. Protein shells assembled from viral coat proteins are an attractive platform for development of new vaccines and other tools such as targeted bioimaging and drug delivery agents. Virus-like particles (VLPs) de...

    Authors: Ilva Liekniņa, Gints Kalniņš, Ināra Akopjana, Jānis Bogans, Mihails Šišovs, Juris Jansons, Jānis Rūmnieks and Kaspars Tārs

    Citation: Journal of Nanobiotechnology 2019 17:61

    Content type: Research

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  12. Nanoscale drug-delivery systems (DDSs) have great promise in tumor diagnosis and treatment. Platelet membrane (PLTM) biomimetic DDSs are expected to enhance retention in vivo and escape uptake by macrophages, ...

    Authors: Haijun Wang, Junzi Wu, Gareth R. Williams, Qing Fan, Shiwei Niu, Jianrong Wu, Xiaotian Xie and Li-Min Zhu

    Citation: Journal of Nanobiotechnology 2019 17:60

    Content type: Research

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  13. Technology enabling the separation of rare circulating tumor cells (CTCs) provides the potential to enhance our knowledge of cancer metastasis and improve the care of cancer patients. Modern detection approach...

    Authors: Zhiming Li, Jun Ruan and Xuan Zhuang

    Citation: Journal of Nanobiotechnology 2019 17:59

    Content type: Research

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  14. Iron oxide nanocomposites have received a great attention for their application in various fields like physics, medicine, biology, and material science etc., due to their unique properties, such as magnetism, ...

    Authors: Hind Baballa Gasmalla, Xiaoquan Lu, Mahgoub Ibrahim Shinger, Lubin Ni, Aadil Nabi Chishti and Guowang Diao

    Citation: Journal of Nanobiotechnology 2019 17:58

    Content type: Research

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  15. Numerous first generation phosphorothioates (PS) and their derivatives have shown promise targeting mRNA for therapeutic applications and also gained market approval for their use as a drug. However, PS have n...

    Authors: Shipra Malik and Raman Bahal

    Citation: Journal of Nanobiotechnology 2019 17:57

    Content type: Research

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  16. Titanium (Ti) and its alloys as bio-implants have excellent biocompatibilities and osteogenic properties after modification of chemical composition and topography via various methods. The corrosion resistance ...

    Authors: Wen-qing Zhu, Shui-yi Shao, Li-na Xu, Wan-qing Chen, Xiao-yu Yu, Kai-ming Tang, Ze-hua Tang, Fa-ming Zhang and Jing Qiu

    Citation: Journal of Nanobiotechnology 2019 17:55

    Content type: Research

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  17. Nanomaterials that exhibit intrinsic enzyme-like characteristics have shown great promise as potential antibacterial agents. However, many of them exhibit inefficient antibacterial activity and biosafety probl...

    Authors: Chen Li, Yurong Sun, Xiaoping Li, Sanhong Fan, Yimin Liu, Xiumei Jiang, Mary D. Boudreau, Yue Pan, Xin Tian and Jun-Jie Yin

    Citation: Journal of Nanobiotechnology 2019 17:54

    Content type: Research

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  18. Soil acidity (and associated Al toxicity) is a major factor limiting crop production worldwide and threatening global food security. Electrostatic layer-by-layer (LBL) self-assembly provides a convenient and v...

    Authors: Yingming Feng, Xuewen Li, Shaoxue Guo, Xingyun Chen, Tingxuan Chen, Yongming He, Sergey Shabala and Min Yu

    Citation: Journal of Nanobiotechnology 2019 17:53

    Content type: Research

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  19. Currently, the main goal of cancer research is to increase longevity of patients suffering malignant cancers. The promising results of BCc1 in vitro and vivo experiments made us look into the effect of BCc1 na...

    Authors: Maryam Hafizi, Somayeh Kalanaky, Hassan moaiery, Maryam Khayamzadeh, Sajad Noorian, Vahid Kaveh, Behrooz Gharib, Hossein Foudazi, Mohsen Razavi, Arash Jenabian, Saeid Salimi, Mohammad Mahdi Adib Sereshki, Hamid Reza Mirzaei, Afshin Zarghi, Saideh Fakharzadeh, Mohammad Hassan Nazaran…

    Citation: Journal of Nanobiotechnology 2019 17:52

    Content type: Research

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  20. Children born with a small or absent ear undergo surgical reconstruction to create a suitable replacement using rib cartilage. To overcome the donor site morbidity and long-term pain of harvesting rib cartilag...

    Authors: Michelle Griffin, Deepak Kalaskar and Peter Butler

    Citation: Journal of Nanobiotechnology 2019 17:51

    Content type: Research

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  21. Improving the water solubility of hydrophobic photosensitizer and increasing its accumulation in tumor tissue are essential for in vivo photodynamic therapy (PDT). Considering commercialization or clinical app...

    Authors: Jihwan Son, Gawon Yi, Moon-Hwa Kwak, Seung Mok Yang, Jae Myung Park, Bo-In Lee, Myung-Gyu Choi and Heebeom Koo

    Citation: Journal of Nanobiotechnology 2019 17:50

    Content type: Research

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  22. The increasing use of gold nanoparticles (AuNPs) in the field of neuroscience instilled hope for their rapid translation to the clinical practice. AuNPs can be engineered to carry therapeutics or diagnostics i...

    Authors: Antonello Spinelli, Maria Girelli, Daniela Arosio, Laura Polito, Paola Podini, Gianvito Martino, Pierfausto Seneci, Luca Muzio and Andrea Menegon

    Citation: Journal of Nanobiotechnology 2019 17:49

    Content type: Research

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  23. Nanoparticles (NPs) are atomic clusters of crystalline or amorphous structure that possess unique physical and chemical properties associated with a size range of between 1 and 100 nm. Their nano-sized dimensi...

    Authors: Magdalena Bamburowicz-Klimkowska, Magdalena Poplawska and Ireneusz P. Grudzinski

    Citation: Journal of Nanobiotechnology 2019 17:48

    Content type: Review

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  24. Glioma is a common brain tumor with a high mortality rate. A small population of cells expressing stem-like cell markers in glioma contributes to drug resistance and tumor recurrence.

    Authors: Xiaofan Zeng, Qi Wang, Xuan Tan, Le Jia, Yuwei Li, Mingdi Hu, Zhijie Zhang, Xicheng Bai, Yanhong Zhu and Xiangliang Yang

    Citation: Journal of Nanobiotechnology 2019 17:47

    Content type: Research

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  25. Silica-ε-polycaprolactone-nanoparticles (SiPCL-NPs) represent a promising tool for laser-tissue soldering in the brain. After release of the SiPCL-NPs in the brain, neuronal differentiation might be modulated....

    Authors: Linda Wiedmer, Angélique D. Ducray, Martin Frenz, Michael H. Stoffel, Hans-Rudolf Widmer and Meike Mevissen

    Citation: Journal of Nanobiotechnology 2019 17:46

    Content type: Research

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  26. Multi-walled carbon nanotube (MWCNT)-induced lung fibrosis leads to health concerns in human. However, the mechanisms underlying fibrosis pathogenesis remains unclear. The adenosine (ADO) is produced in respon...

    Authors: Biying Liu, Qizheng Bing, Siyu Li, Bing Han, Jingjing Lu, Ruiqi Baiyun, Xiaoya Zhang, Yueying Lv, Hao Wu and Zhigang Zhang

    Citation: Journal of Nanobiotechnology 2019 17:45

    Content type: Research

    Published on:

  27. The combination of multiple chemotherapeutics has been used in the clinic for enhanced cancer chemotherapy, however, frequent relapse, chemo-resistance and side effects remains therapeutic hurdles. Thus, the d...

    Authors: Falian Zhu, Guozhu Tan, Yingtao Zhong, Yaodong Jiang, Lulu Cai, Zhiqiang Yu, Shuwen Liu and Fei Ren

    Citation: Journal of Nanobiotechnology 2019 17:44

    Content type: Research

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  28. Campylobacteriosis is a zoonotic infectious disease that can be mostly undiagnosed or unreported due to fastidious Campylobacter species. The aim of this study was to develop a simple, sensitive, and quick assay ...

    Authors: Saeed Shams, Bita Bakhshi, Tahereh Tohidi Moghadam and Mehrdad Behmanesh

    Citation: Journal of Nanobiotechnology 2019 17:43

    Content type: Research

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  29. Sweat, as an easily accessible bodily fluid, is enriched with a lot of physiological and health information. A portable and wearable sweat sensor is an important device for an on-body health monitoring. Howeve...

    Authors: Min Zhang, Shuai Guo, Dieter Weller, Yan Hao, Xianshuang Wang, Chunjie Ding, Ke Chai, Bingsuo Zou and Ruibin Liu

    Citation: Journal of Nanobiotechnology 2019 17:42

    Content type: Research

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  30. Cerium oxide nanoparticles (CeO2 NPs) have potential application for use in biomedical and in various consumer products. However, it is largely unclear whether CeO2 NPs have effects on male reproductive function.

    Authors: Fenju Qin, Tao Shen, Jinlin Li, Junchao Qian, Jie Zhang, Guangming Zhou and Jian Tong

    Citation: Journal of Nanobiotechnology 2019 17:41

    Content type: Research

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  31. Human mesenchymal stem cells (MSCs) have drawn much attention in the field of regenerative medicine for their immunomodulatory and anti-inflammatory effects. MSCs possess specific tumor-oriented migration and ...

    Authors: Gabrielis Kundrotas, Vitalijus Karabanovas, Marijus Pleckaitis, Marina Juraleviciute, Simona Steponkiene, Zivile Gudleviciene and Ricardas Rotomskis

    Citation: Journal of Nanobiotechnology 2019 17:39

    Content type: Research

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  32. Rapid and sensitive detection of H2O2 especially endogenous H2O2 is of great importance for series of industries including disease diagnosis and therapy. In this work, uniform FePt nanoparticles are successfully ...

    Authors: Zunfu Hu, Zhichao Dai, Xiaowei Hu, Baochan Yang, Qingyun Liu, Chuanhui Gao, Xiuwen Zheng and Yueqin Yu

    Citation: Journal of Nanobiotechnology 2019 17:38

    Content type: Research

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  33. Magnetosomes (also called bacterial magnetic nanoparticles; BMPs) are biomembrane-coated nanoparticles synthesized by magnetotactic bacteria (MTB). Engineered BMPs fused to protein A (termed ∆F-BMP-FA) bind an...

    Authors: Junjie Xu, Lingzi Liu, Jinxin He, Shijiao Ma, Shuli Li, Zhanhui Wang, Ting Xu, Wei Jiang, Ying Wen, Ying Li, Jiesheng Tian and Feng Li

    Citation: Journal of Nanobiotechnology 2019 17:37

    Content type: Research

    Published on:

  34. In the original publication of the article [1], the Fig. 8c and d was published with incorrect values. The corrected Fig. 8c and d is given below:

    Authors: Wei Hong, Lipeng Liu, Yining Zhao, Yinghui Liu, Dexian Zhang and Mingchun Liu

    Citation: Journal of Nanobiotechnology 2019 17:36

    Content type: Correction

    Published on:

    The original article was published in Journal of Nanobiotechnology 2018 16:66

  35. Sensitive and specific antibodies can be used as essential probes to develop competitive enzyme-linked immunosorbent assay (cELISA). However, traditional antibodies are difficult to produce, only available in ...

    Authors: Yamin Sheng, Kun Wang, Qizhong Lu, Pinpin Ji, Baoyuan Liu, Jiahong Zhu, Qingyuan Liu, Yani Sun, Jingfei Zhang, En-Min Zhou and Qin Zhao

    Citation: Journal of Nanobiotechnology 2019 17:35

    Content type: Research

    Published on:

  36. Natural teeth are supported by connective tissue collagen fibers that insert perpendicularly in the tooth cementum. Perpendicular insertion plays an important role in the maintenance of the junction between th...

    Authors: Toshiki Nojiri, Chia-Yu Chen, David M. Kim, John Da Silva, Cliff Lee, Masahiko Maeno, Arthur A. McClelland, Bryan Tse, Shigemi Ishikawa-Nagai, Wataru Hatakeyama, Hisatomo Kondo and Masazumi Nagai

    Citation: Journal of Nanobiotechnology 2019 17:34

    Content type: Research

    Published on:

  37. After publication of the original article [1], the authors found that Figure 2e (Hsp70-Ch-Lf-ZF in Jurkat cells, 2 h), Figure 5b (HSP70-Lf-ZF) and Figure 5c (control) contained incorrect images. This does not ...

    Authors: Rajneesh Chaudhary, Kislay Roy, Rupinder Kaur Kanwar, Ken Walder and Jagat Rakesh Kanwar

    Citation: Journal of Nanobiotechnology 2019 17:33

    Content type: Correction

    Published on:

    The original article was published in Journal of Nanobiotechnology 2016 14:6

  38. The conventional approaches to assess the potential cytotoxic effects of nanomaterials (NMs) mainly rely on in vitro biochemical assays. These assays are strongly dependent on the properties of the nanomateria...

    Authors: Homero F. Pastrana, Alexander X. Cartagena-Rivera, Arvind Raman and Alba Ávila

    Citation: Journal of Nanobiotechnology 2019 17:32

    Content type: Research

    Published on:

  39. Circulating tumor cells (CTCs) comprise the high metastatic potential population of cancer cells in the blood circulation of humans; they have become the established biomarkers for cancer diagnosis, individual...

    Authors: Chia-Cheng Yu, Yi-Wen Chen, Po-Ying Yeh, Yu-Sheng Hsiao, Wei-Ting Lin, Chiung-Wen Kuo, Di-Yen Chueh, Yun-Wen You, Jing-Jong Shyue, Ying-Chih Chang and Peilin Chen

    Citation: Journal of Nanobiotechnology 2019 17:31

    Content type: Research

    Published on:

  40. Malignant glioma is the most common and deadliest brain cancer due to the obstacle from indistinct tumor margins for surgical excision and blood brain barrier (BBB) for chemotherapy. Here, we designed and prep...

    Authors: Lingzhou Zhao, Yujie Li, Jingyi Zhu, Na Sun, Ningning Song, Yan Xing, He Huang and Jinhua Zhao

    Citation: Journal of Nanobiotechnology 2019 17:30

    Content type: Research

    Published on:

  41. Accumulating evidence shows that microRNA-210 (miR-210) holds great promise to improve angiogenesis for brain tissue repair after cerebral ischemia. However, safe and efficient delivery of miR-210 via intraven...

    Authors: Huixin Zhang, Jin Wu, Jiahuan Wu, Qi Fan, Jingchao Zhou, Junwen Wu, Sichen Liu, Jie Zang, Jinhai Ye, Ming Xiao, Tian Tian and Jun Gao

    Citation: Journal of Nanobiotechnology 2019 17:29

    Content type: Research

    Published on:

  42. Following publication of this article [1] we found a typographical error in the results reported in the abstract. The corrected sentences should read as below:

    Authors: Dennis Kreft, Ying Wang, Michael Rattay, Katja Toensing and Dario Anselmetti

    Citation: Journal of Nanobiotechnology 2019 17:28

    Content type: Correction

    Published on:

    The original article was published in Journal of Nanobiotechnology 2018 16:56

  43. Theranostics application of superparamagnetic nanoparticles based on magnetite and maghemite is impeded by their toxicity. The use of additional protective shells significantly reduced the magnetic properties ...

    Authors: Anastasiia Garanina, Igor Kireev, Oxana Zhironkina, Olga Strelkova, Anton Shakhov, Irina Alieva, Valery Davydov, Sankaran Murugesan, Valery Khabashesku, Alexander Majouga, Viatcheslav Agafonov and Rustem Uzbekov

    Citation: Journal of Nanobiotechnology 2019 17:27

    Content type: Research

    Published on:

  44. The detection of circulating tumor cells (CTCs) is very important for cancer diagnosis. CTCs can travel from primary tumors through the circulation to form secondary tumor colonies via bloodstream extravasatio...

    Authors: Chiung Wen Kuo, Di-Yen Chueh and Peilin Chen

    Citation: Journal of Nanobiotechnology 2019 17:26

    Content type: Research

    Published on:

  45. A cationic liposome-PEG-PEI complex (LPPC) was employed as a carrier for achieving targeted delivery of drug to human epidermal growth factor receptor-2 (HER2/neu)-expressing breast cancer cells. LPPC can be e...

    Authors: Yu-Ling Lin, Nu-Man Tsai, Chia-Hung Chen, Yen-Ku Liu, Chung-Jen Lee, Yi-Lin Chan, Yu-Shan Wang, Yuan-Ching Chang, Chi-Hsin Lin, Tse-Hung Huang, Chao Ching Wang, Kwan-Hwa Chi and Kuang-Wen Liao

    Citation: Journal of Nanobiotechnology 2019 17:25

    Content type: Research

    Published on:

  46. Silica nanoparticles (SiNPs) are widely used for biosensing and diagnostics, and for the targeted delivery of therapeutic agents. Safety concerns about the biomedical and clinical applications of SiNPs have be...

    Authors: Kyungmin Lee, Jangwook Lee, Minjeong Kwak, Young-Lai Cho, Byungtae Hwang, Min Ji Cho, Na Geum Lee, Jongjin Park, Sang-Hyun Lee, Jong-Gil Park, Yeon-Gu Kim, Jang-Seong Kim, Tae-Su Han, Hyun-Soo Cho, Young-Jun Park, Seon-Jin Lee…

    Citation: Journal of Nanobiotechnology 2019 17:24

    Content type: Research

    Published on:

  47. In recent years, multifunctional theranostic nanoparticles have been fabricated by integrating imaging and therapeutic moieties into one single nano-formulations. However, Complexity of production and safety i...

    Authors: Xianlei Li, Xuan Wang, Caiyan Zhao, Leihou Shao, Jianqing Lu, Yujia Tong, Long Chen, Xinyue Cui, Huiling Sun, Junxing Liu, Mingjun Li, Xiongwei Deng and Yan Wu

    Citation: Journal of Nanobiotechnology 2019 17:23

    Content type: Research

    Published on:

  48. Human plasma gelsolin (pGSN) is a multifunctional actin-binding protein involved in a variety of biological processes, including neutralization of pro-inflammatory molecules such as lipopolysaccharide (LPS) an...

    Authors: Ewelina Piktel, Urszula Wnorowska, Mateusz Cieśluk, Piotr Deptula, Katarzyna Pogoda, Iwona Misztalewska-Turkowicz, Paulina Paprocka, Katarzyna Niemirowicz-Laskowska, Agnieszka Z. Wilczewska, Paul A. Janmey and Robert Bucki

    Citation: Journal of Nanobiotechnology 2019 17:22

    Content type: Research

    Published on:

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