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  1. Acute lung injury (ALI), a severe health-threatening disease, has a risk of causing chronic pulmonary fibrosis. Informative and powerful evidence suggests that inflammation and oxidative stress play a central ...

    Authors: Yi-Bing Chen, Ya-Bin Zhang, Yu-Le Wang, Prabhleen Kaur, Bo-Guang Yang, Yan Zhu, Lei Ye and Yuan-Lu Cui
    Citation: Journal of Nanobiotechnology 2022 20:272
  2. NRF2 is the key antioxidant molecule to maintain redox homeostasis, however the intrinsic mechanisms of NRF2 activation in the context of nanoparticles (NPs) exposure remain unclear. In this study, we revealed...

    Authors: Na Li, Hang Du, Lejiao Mao, Ge Xu, Mengling Zhang, Yinzhen Fan, Xiaomei Dong, Lijun Zheng, Bin Wang, Xia Qin, Xuejun Jiang, Chengzhi Chen, Zhen Zou and Jun Zhang
    Citation: Journal of Nanobiotechnology 2022 20:270
  3. RNA viruses periodically trigger pandemics of severe human diseases, frequently causing enormous economic losses. Here, a nucleic acid extraction-free and amplification-free RNA virus testing probe was propose...

    Authors: Fuyu Du, Weijie Zhang, Huimin Yao, Yuqiong Xia, Xianghan Zhang, Peng Yang and Pengbo Ning
    Citation: Journal of Nanobiotechnology 2022 20:269
  4. Excessive accumulation of reactive oxygen species (ROS) has been documented as the crucial cellular mechanism of cisplatin-induced ototoxicity. However, numerous antioxidants have failed in clinical studies pa...

    Authors: Jiayi Gu, Xueling Wang, Yuming Chen, Ke Xu, Dehong Yu and Hao Wu
    Citation: Journal of Nanobiotechnology 2022 20:268
  5. Triple-negative breast cancer (TNBC) is a highly heterogeneous breast cancer subtype with poor prognosis. Although anatomical imaging figures prominently for breast lesion screening, TNBC is often misdiagnosed...

    Authors: Natacha Jugniot, Tarik F. Massoud, Jeremy J. Dahl and Ramasamy Paulmurugan
    Citation: Journal of Nanobiotechnology 2022 20:267
  6. Surgical resection to achieve tumor-free margins represents a difficult clinical scenario for patients with hepatocellular carcinoma. While post-surgical treatments such as chemotherapy and radiotherapy can de...

    Authors: Wentao Dang, Wei-Chih Chen, Enguo Ju, Yanteng Xu, Kai Li, Haixia Wang, Kun Wang, Shixian Lv, Dan Shao, Yu Tao and Mingqiang Li
    Citation: Journal of Nanobiotechnology 2022 20:266
  7. Overproduced reactive oxygen and reactive nitrogen species (RONS) in the brain are involved in the pathogenesis of several neurological diseases, such as Alzheimer's disease, Parkinson's disease, traumatic bra...

    Authors: Yanping Jiang, Yiyuan Kang, Jia Liu, Suhan Yin, Zhendong Huang and Longquan Shao
    Citation: Journal of Nanobiotechnology 2022 20:265
  8. The application of chemodynamic therapy (CDT) for cancer is a serious challenge owing to the low efficiency of the Fenton catalyst and insufficient H2O2 expression in cells. Herein, we fabricated a PDGFB targetin...

    Authors: Caiyun Zhang, Zhiguo Leng, Yinfeng Wang, Lang Ran, Xia Qin, Huan Xin, Xiaotong Xu, Guilong Zhang and Zhaowei Xu
    Citation: Journal of Nanobiotechnology 2022 20:264
  9. A balanced endogenous level of bioavailable nitric oxide (NO) plays a key role in maintaining cardiovascular homeostasis. The bioactive NO level in the cardiomyocytes was much reduced during sepsis. However, i...

    Authors: Minzhi Ouyang, Xiangnan Ouyang, Zefang Peng, Minghui Liu, Ganqiong Xu, Zhen Zou, Ming Zhang and Quanliang Shang
    Citation: Journal of Nanobiotechnology 2022 20:263
  10. Interest in nanomaterials and especially nanoparticles has exploded in the past decades primarily due to their novel or enhanced physical and chemical properties compared to bulk material. These extraordinary ...

    Authors: Nadeem Joudeh and Dirk Linke
    Citation: Journal of Nanobiotechnology 2022 20:262
  11. Adoptive cell therapy (ACT) was one of the most promising anti-tumor modalities that has been confirmed to be especially effective in treating hematological malignancies. However, the clinical efficacy of ACT ...

    Authors: Zhenyu Luo, Lihua Luo, Yichao Lu, Chunqi Zhu, Bing Qin, Mengshi Jiang, Xiang Li, Yingying Shi, Junlei Zhang, Yu Liu, Xinyu Shan, Hang Yin, Guannan Guan, Yongzhong Du, Ningtao Cheng and Jian You
    Citation: Journal of Nanobiotechnology 2022 20:261
  12. Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), seriously threatens human life and health. The correct folding and polymerization of the receptor-bi...

    Authors: Zhongqian Yang, Liangqun Hua, Mengli Yang, Weiran Li, Zhaoling Ren, Xiao Zheng, Haoqian Chen, Qiong Long, Hongmei Bai, Weiwei Huang and Yanbing Ma
    Citation: Journal of Nanobiotechnology 2022 20:260
  13. Patients with diabetic foot ulcers usually suffer from inefficient epithelisation and angiogenesis accompanied by chronic wound healing. Diabetic foot ulcers remain a major challenge in clinical medicine; howe...

    Authors: Pei Wang, Yun Wang, Yang Yi, Yan Gong, Haoran Ji, Yuci Gan, Fei Xie, Jinchen Fan and Xiansong Wang
    Citation: Journal of Nanobiotechnology 2022 20:259
  14. Cisplatin, the alkylating agent of platinum(II) (Pt(II)), is the most common antitumor drug in clinic; however, it has many side effects, therefore it is higly desired to develop low toxicity platinum(IV) (Pt(...

    Authors: Xing Li, Lingpu Zhang, Tuo Li, Shumu Li, Wenjing Wu, Lingyu Zhao, Peng Xie, Jinqi Yang, Peipei Li, Yangyang Zhang, Haihua Xiao, Yingjie Yu and Zhenwen Zhao
    Citation: Journal of Nanobiotechnology 2022 20:258
  15. Ischemic stroke is one of the main causes of death and disability in the world. The treatment for ischemic stroke is to restore blood perfusion as soon as possible. However, when ischemic brain tissue is re-pe...

    Authors: Daozhou Liu, Qifeng Ji, Ying Cheng, Miao Liu, Bangle Zhang, Qibing Mei, Menglei Huan and Siyuan Zhou
    Citation: Journal of Nanobiotechnology 2022 20:256
  16. Engineering the surface of materials with desired multifunctionalities is an effective way to fight against multiple adverse factors during tissue repair process. Recently, metal-polyphenol networks (MPNs) hav...

    Authors: Xinxiu Cheng, Yaxin Zhu, Sicheng Tang, Ruofei Lu, Xiaoqiang Zhang, Na Li and Xingjie Zan
    Citation: Journal of Nanobiotechnology 2022 20:255
  17. Nano-priming is an innovative seed priming technology that helps to improve seed germination, seed growth, and yield by providing resistance to various stresses in plants. Nano-priming is a considerably more e...

    Authors: Shivraj Hariram Nile, Muthu Thiruvengadam, Yao Wang, Ramkumar Samynathan, Mohammad Ali Shariati, Maksim Rebezov, Arti Nile, Meihong Sun, Baskar Venkidasamy, Jianbo Xiao and Guoyin Kai
    Citation: Journal of Nanobiotechnology 2022 20:254
  18. Methotrexate (MTX) has been highlighted for Rheumatoid arthritis (RA) treatment, however, MTX does not accumulate well at inflamed sites, and long-term administration in high doses leads to severe side effects...

    Authors: Yao Wang, Ming Jia, Xiu Zheng, Chenglong Wang, Yun Zhou, Hong Pan, Yan Liu, Ji Lu, Zhiqiang Mei and Chunhong Li
    Citation: Journal of Nanobiotechnology 2022 20:253
  19. Extracellular vesicles (EVs) are promising drug carriers of photosensitizers for photodynamic therapy (PDT) in cancer treatment, due to their ability to circulate in blood and enter cells efficiently. The ther...

    Authors: Ruben V. Huis in ‘t Veld, Pablo Lara, Martine J. Jager, Roman I. Koning, Ferry Ossendorp and Luis J. Cruz
    Citation: Journal of Nanobiotechnology 2022 20:252
  20. At present, patients with myocardial infarction remain an increased risk for myocardial ischemia/reperfusion injury (MI/RI). There lacks effectively method to treat MI/RI in clinic. For the treatment of MI/RI,...

    Authors: Fangyuan Li, Daozhou Liu, Miao Liu, Qifeng Ji, Bangle Zhang, Qibing Mei, Ying Cheng and Siyuan Zhou
    Citation: Journal of Nanobiotechnology 2022 20:251
  21. Applying traditional fluorescence navigation technologies in hepatocellular carcinoma is severely restricted by high false-positive rates, variable tumor differentiation, and unstable fluorescence performance.

    Authors: Pan He, Yongfu Xiong, Jinfa Ye, Biaoqi Chen, Hongwei Cheng, Hao Liu, Yating Zheng, Chengchao Chu, Jingsong Mao, Aizheng Chen, Yang Zhang, Jingdong Li, Jie Tian and Gang Liu
    Citation: Journal of Nanobiotechnology 2022 20:250
  22. Our previous studies suggest that human fat extract (FE) contains a variety of angiogenic factors and may provide an alternative treatment option for stroke. However, the therapeutic effect is largely limited ...

    Authors: Cheng Wang, Xuewei Yang, Yixu Jiang, Lin Qi, Deli Zhuge, Tongtong Xu, Yiyan Guo, Mingwu Deng, Wenjie Zhang, Dongyan Tian, Qingqing Yin, Li Li, Zhijun Zhang, Yongting Wang, Guo-Yuan Yang, Yijie Chen…
    Citation: Journal of Nanobiotechnology 2022 20:249
  23. Exosomes are nanoscale monolayer membrane vesicles that are actively endogenously secreted by mammalian cells. Currently, multifunctional exosomes with tumor-targeted imaging and therapeutic potential have aro...

    Authors: Congcong Wang, Ning Li, Yutian Li, Shasha Hou, Wenxin Zhang, Zhaowei Meng, Shen Wang, Qiang Jia, Jian Tan, Renfei Wang and Ruiguo Zhang
    Citation: Journal of Nanobiotechnology 2022 20:247
  24. Liquid metal (LM) can be integrated into microfluidic channel, bringing new functionalities of microfluidics and opening a new window for soft microfluidic electronics, due to the superior advantages of the co...

    Authors: Yang Zhang, Haowei Duan, Guoqiang Li, Maoyu Peng, Xing Ma, Ming Li and Sheng Yan
    Citation: Journal of Nanobiotechnology 2022 20:246
  25. Immunotherapies have been gaining attention for the prevention of cancer recurrence and metastasis. Cancer immunotherapy can induce memory cells to target cancer-specific antigens and, thus, selectively kill c...

    Authors: Juyoung Hwang, Eun-Koung An, Wei Zhang, Hyo Jeong Kim, Youngho Eom and Jun-O. Jin
    Citation: Journal of Nanobiotechnology 2022 20:245
  26. The diversified combination of nanostructure and material has received considerable attention from researchers to exploit advanced functional materials. In drug delivery systems, the hydrophilicity and sustain...

    Authors: Yubo Liu, Xiaohong Chen, Yuhang Gao, Deng-Guang Yu and Ping Liu
    Citation: Journal of Nanobiotechnology 2022 20:244
  27. Triple-negative breast cancer (TNBC) is more prone to distant metastasis and visceral recurrence in comparison to other breast cancer subtypes, and is related to dismal prognosis. Nevertheless, TNBC has an und...

    Authors: Fuqiang Shao, Zhidi Pan, Yu Long, Ziyang Zhu, Kun Wang, Hao Ji, Ke Zhu, Wenyu Song, Yangmeihui Song, Xiangming Song, Yongkang Gai, Qingyao Liu, Chunxia Qin, Dawei Jiang, Jianwei Zhu and Xiaoli Lan
    Citation: Journal of Nanobiotechnology 2022 20:243
  28. The exchange of mitochondria reportedly plays an important role in cell–cell communication in the central nervous system (CNS). The transfer of fragmented and dysfunctional astrocytic mitochondria into neurons...

    Authors: Wei Liu, Chang Su, Yao Qi, Jia Liang, Liang Zhao and Yijie Shi
    Citation: Journal of Nanobiotechnology 2022 20:242
  29. Periprosthetic osteolysis (PPO) triggered by wear particles is the most severe complication of total joint replacement (TJR) surgeries, representing the major cause of implant failure, which is public health c...

    Authors: Wei Wang, Xiaolong Liang, Xin Liu, Jiaxiang Bai, Wei Zhang, Wenming Li, Tianhao Wang, Meng Li, Zerui Wu, Liang Chen, Huilin Yang, Ye Gu, Yunxia Tao, Jun Zhou, Huaiyu Wang and Dechun Geng
    Citation: Journal of Nanobiotechnology 2022 20:241
  30. Postoperative chemotherapy for gastric cancer often causes multidrug resistance (MDR), which has serious consequences for therapeutic effects. Individualized treatment based on accurate monitoring of MDR will ...

    Authors: Hanrui Li, Xiaoxia Cai, Tong Yi, Yun Zeng, Jingwen Ma, Lei Li, Liaojun Pang, Na Li, Hao Hu and Yonghua Zhan
    Citation: Journal of Nanobiotechnology 2022 20:240
  31. High-quality cutaneous wound healing is associated with rapid wound closure and a comfortable healing process. Currently, exosomes derived from mesenchymal stem cells displayed a prominent therapeutic effect o...

    Authors: Yunyi Xie, Le Yu, Zhilan Cheng, Yingying Peng, Zeyuan Cao, Beichen Chen, Yihong Duan and Yan Wang
    Citation: Journal of Nanobiotechnology 2022 20:239
  32. Tumor killing and wound healing are two complementary and influential processes during the treatment of melanoma. Herein, a two-layered microneedle platform was developed with bifunctional effect of chemo-phot...

    Authors: Yue Shan, Bowen Tan, Min Zhang, Xi Xie and Jinfeng Liao
    Citation: Journal of Nanobiotechnology 2022 20:238
  33. Nonalcoholic fatty liver disease (NAFLD) is a metabolic disease mainly on account of hypercholesterolemia and may progress to cirrhosis and hepatocellular carcinoma. The discovery of effective therapy for NAFL...

    Authors: Xiaozhi Hu, Jiajun Fan, Qianqian Ma, Lei Han, Zhonglian Cao, Caili Xu, Jingyun Luan, Guangjun Jing, Yanyang Nan, Tao Wu, Yuting Zhang, Hanqi Wang, Yuanzhen Zhang and Dianwen Ju
    Citation: Journal of Nanobiotechnology 2022 20:237
  34. Nanomedicines (NMs) have emerged as an efficient approach for developing novel treatment strategies against a variety of diseases. Over the past few decades, NM formulations have received great attention, and ...

    Authors: Ruslan G. Tuguntaev, Abid Hussain, Chenxing Fu, Haoting Chen, Ying Tao, Yan Huang, Lu Liu, Xing-Jie Liang and Weisheng Guo
    Citation: Journal of Nanobiotechnology 2022 20:236
  35. MXenes with interesting optical and electrical properties have been attractive in biomedical applications such as antibacterial and anticancer agents, but their low photogeneration efficiency of reactive oxyge...

    Authors: Ya-Ju Hsu, Amit Nain, Yu-Feng Lin, Yu-Ting Tseng, Yu-Jia Li, Arumugam Sangili, Pavitra Srivastava, Hui-Ling Yu, Yu-Fen Huang, Chih-Ching Huang and Huan-Tsung Chang
    Citation: Journal of Nanobiotechnology 2022 20:235
  36. Gastric cancer (GC) is a highly heterogeneous disease with many different histological and molecular subtypes. Due to their reduced systemic adverse effects, nanoformulation agents have attracted increasing at...

    Authors: Jiale Zou, Shuang Wang, Ningli Chai, Hua Yue, Peng Ye, Peilin Guo, Feng Li, Bo Wei, Guanghui Ma, Wei Wei and Enqiang Linghu
    Citation: Journal of Nanobiotechnology 2022 20:233
  37. The complicated hyperglycaemic and chronic inflammation of diabetic wounds in orthopaedic surgery leads to dysregulated immune cell function and potential infection risk. Immune interventions in diabetic wound...

    Authors: Jiawei Mei, Jun Zhou, Lingtong Kong, Yong Dai, Xianzuo Zhang, Wenqi Song and Chen Zhu
    Citation: Journal of Nanobiotechnology 2022 20:232
  38. Chikungunya virus (CHIKV) is a re-emerged mosquito-borne alphavirus that can cause musculoskeletal diseases, imposing a substantial threat to public health globally. High-affinity antibodies are need for diagn...

    Authors: Qianlin Li, Fuqiang Zhang, Yi Lu, Huan Hu, Jin Wang, Cheng Guo, Qiang Deng, Conghui Liao, Qin Wu, Tingsong Hu, Zeliang Chen and Jiahai Lu
    Citation: Journal of Nanobiotechnology 2022 20:231
  39. Chemodynamic therapy (CDT) relying on intracellular iron ions and H2O2 is a promising therapeutic strategy due to its tumor selectivity, which is limited by the not enough metal ions or H2O2 supply of tumor micro...

    Authors: Xiao-Xin Yang, Xiang Xu, Mei-Fang Wang, Hua-Zhen Xu, Xing-Chun Peng, Ning Han, Ting-Ting Yu, Liu-Gen Li, Qi-Rui Li, Xiao Chen, Yu Wen and Tong-Fei Li
    Citation: Journal of Nanobiotechnology 2022 20:230
  40. Authors: Iris M. Hagemans, Peter J. Wierstra, Kas Steuten, Janneke D. M. Molkenboer-Kuenen, Duco van Dalen, Martin ter Beest, Johan M. S. van der Schoot, Olga Ilina, Martin Gotthardt, Carl G. Figdor, Ferenc A. Scheeren, Sandra Heskamp and Martijn Verdoes
    Citation: Journal of Nanobiotechnology 2022 20:229

    The original article was published in Journal of Nanobiotechnology 2022 20:64

  41. Immunotherapeutic interventions represent a promising approach to treating cancer, with strategies such as immune checkpoint blockade (ICB), immunogenic sonodynamic therapy (SDT), and immune adjuvant T cell de...

    Authors: Jiali Luo, Xue Wang, Zhan Shi, Yiqing Zeng, Liangcan He, Jing Cao, Yu Sun, Tao Zhang and Pintong Huang
    Citation: Journal of Nanobiotechnology 2022 20:228
  42. There has been growing concern regarding the impact of air pollution, especially fine dust, on human health. However, it is difficult to estimate the toxicity of fine dust on the human body because of its dive...

    Authors: Taewoong Son, Youn-Joo Cho, Hyunseung Lee, Mi Young Cho, Byeongwoo Goh, Hyun Min Kim, Phan Thi Ngoc Hoa, Sun-Hee Cho, Young-Jun Park, Hye Sun Park and Kwan Soo Hong
    Citation: Journal of Nanobiotechnology 2022 20:227
  43. Conventional chemotherapy has poor efficacy in triple-negative breast cancer (TNBC) which is highly heterogeneous and aggressive. Imaging-guided therapy is usually combined with diverse treatment modalities, c...

    Authors: Qi Xie, Shichao Li, Xingxing Feng, Jingyu Shi, Yang Li, Guanjie Yuan, Conglian Yang, Yaqi Shen, Li Kong and Zhiping Zhang
    Citation: Journal of Nanobiotechnology 2022 20:226
  44. By hindering energy supply pathway for cancer cells, an alternative therapeutic strategy modality is put forward: tumor starvation therapy. And yet only in this blockade of glucose supply which is far from eno...

    Authors: Xuan Wang, Yunhao Li, Fan Jia, Xinyue Cui, Zian Pan and Yan Wu
    Citation: Journal of Nanobiotechnology 2022 20:225
  45. Magnetic materials mediated by mechanical forces to combat cancer cells are currently attracting attention. Firstly, the magnetic force penetrates deeper into tissues than the NIR laser alone to destroy tumour...

    Authors: Kai Wu, Ali Mohsin, Waqas Qamar Zaman, Zefei Zhang, Wenyan Guan, Maoquan Chu, Yingping Zhuang and Meijin Guo
    Citation: Journal of Nanobiotechnology 2022 20:224
  46. Tumor microenvironment (TME), characterized by high glutathione (GSH), high hydrogen peroxide (H2O2) and acidic pH levels, is favorable for the growth, invasion and metastasis of cancer cells. Taking advantage of...

    Authors: Ruiyi Zhang, Teng Liu, Wanzhen Li, Zhiyuan Ma, Pei Pei, Weiwei Zhang, Kai Yang and Yugui Tao
    Citation: Journal of Nanobiotechnology 2022 20:223
  47. Osteoarthritis (OA) is a common degenerative joint disease that can lead to disability. Blocking the complex malignant feedback loop system dominated by oxidative stress and pro-inflammatory factors is the key...

    Authors: Chunrong Zhu, Shangcong Han, Xianhu Zeng, Chunxiao Zhu, Yuji Pu and Yong Sun
    Citation: Journal of Nanobiotechnology 2022 20:221

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