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  1. Tumor killing and wound healing are two complementary and influential processes during the treatment of melanoma. Herein, a two-layered microneedle platform was developed with bifunctional effect of chemo-phot...

    Authors: Yue Shan, Bowen Tan, Min Zhang, Xi Xie and Jinfeng Liao
    Citation: Journal of Nanobiotechnology 2022 20:238
  2. Nonalcoholic fatty liver disease (NAFLD) is a metabolic disease mainly on account of hypercholesterolemia and may progress to cirrhosis and hepatocellular carcinoma. The discovery of effective therapy for NAFL...

    Authors: Xiaozhi Hu, Jiajun Fan, Qianqian Ma, Lei Han, Zhonglian Cao, Caili Xu, Jingyun Luan, Guangjun Jing, Yanyang Nan, Tao Wu, Yuting Zhang, Hanqi Wang, Yuanzhen Zhang and Dianwen Ju
    Citation: Journal of Nanobiotechnology 2022 20:237
  3. Gastric cancer (GC) is a highly heterogeneous disease with many different histological and molecular subtypes. Due to their reduced systemic adverse effects, nanoformulation agents have attracted increasing at...

    Authors: Jiale Zou, Shuang Wang, Ningli Chai, Hua Yue, Peng Ye, Peilin Guo, Feng Li, Bo Wei, Guanghui Ma, Wei Wei and Enqiang Linghu
    Citation: Journal of Nanobiotechnology 2022 20:233
  4. The complicated hyperglycaemic and chronic inflammation of diabetic wounds in orthopaedic surgery leads to dysregulated immune cell function and potential infection risk. Immune interventions in diabetic wound...

    Authors: Jiawei Mei, Jun Zhou, Lingtong Kong, Yong Dai, Xianzuo Zhang, Wenqi Song and Chen Zhu
    Citation: Journal of Nanobiotechnology 2022 20:232
  5. Chikungunya virus (CHIKV) is a re-emerged mosquito-borne alphavirus that can cause musculoskeletal diseases, imposing a substantial threat to public health globally. High-affinity antibodies are need for diagn...

    Authors: Qianlin Li, Fuqiang Zhang, Yi Lu, Huan Hu, Jin Wang, Cheng Guo, Qiang Deng, Conghui Liao, Qin Wu, Tingsong Hu, Zeliang Chen and Jiahai Lu
    Citation: Journal of Nanobiotechnology 2022 20:231
  6. Chemodynamic therapy (CDT) relying on intracellular iron ions and H2O2 is a promising therapeutic strategy due to its tumor selectivity, which is limited by the not enough metal ions or H2O2 supply of tumor micro...

    Authors: Xiao-Xin Yang, Xiang Xu, Mei-Fang Wang, Hua-Zhen Xu, Xing-Chun Peng, Ning Han, Ting-Ting Yu, Liu-Gen Li, Qi-Rui Li, Xiao Chen, Yu Wen and Tong-Fei Li
    Citation: Journal of Nanobiotechnology 2022 20:230
  7. Authors: Iris M. Hagemans, Peter J. Wierstra, Kas Steuten, Janneke D. M. Molkenboer-Kuenen, Duco van Dalen, Martin ter Beest, Johan M. S. van der Schoot, Olga Ilina, Martin Gotthardt, Carl G. Figdor, Ferenc A. Scheeren, Sandra Heskamp and Martijn Verdoes
    Citation: Journal of Nanobiotechnology 2022 20:229

    The original article was published in Journal of Nanobiotechnology 2022 20:64

  8. Immunotherapeutic interventions represent a promising approach to treating cancer, with strategies such as immune checkpoint blockade (ICB), immunogenic sonodynamic therapy (SDT), and immune adjuvant T cell de...

    Authors: Jiali Luo, Xue Wang, Zhan Shi, Yiqing Zeng, Liangcan He, Jing Cao, Yu Sun, Tao Zhang and Pintong Huang
    Citation: Journal of Nanobiotechnology 2022 20:228
  9. There has been growing concern regarding the impact of air pollution, especially fine dust, on human health. However, it is difficult to estimate the toxicity of fine dust on the human body because of its dive...

    Authors: Taewoong Son, Youn-Joo Cho, Hyunseung Lee, Mi Young Cho, Byeongwoo Goh, Hyun Min Kim, Phan Thi Ngoc Hoa, Sun-Hee Cho, Young-Jun Park, Hye Sun Park and Kwan Soo Hong
    Citation: Journal of Nanobiotechnology 2022 20:227
  10. Conventional chemotherapy has poor efficacy in triple-negative breast cancer (TNBC) which is highly heterogeneous and aggressive. Imaging-guided therapy is usually combined with diverse treatment modalities, c...

    Authors: Qi Xie, Shichao Li, Xingxing Feng, Jingyu Shi, Yang Li, Guanjie Yuan, Conglian Yang, Yaqi Shen, Li Kong and Zhiping Zhang
    Citation: Journal of Nanobiotechnology 2022 20:226
  11. By hindering energy supply pathway for cancer cells, an alternative therapeutic strategy modality is put forward: tumor starvation therapy. And yet only in this blockade of glucose supply which is far from eno...

    Authors: Xuan Wang, Yunhao Li, Fan Jia, Xinyue Cui, Zian Pan and Yan Wu
    Citation: Journal of Nanobiotechnology 2022 20:225
  12. Magnetic materials mediated by mechanical forces to combat cancer cells are currently attracting attention. Firstly, the magnetic force penetrates deeper into tissues than the NIR laser alone to destroy tumour...

    Authors: Kai Wu, Ali Mohsin, Waqas Qamar Zaman, Zefei Zhang, Wenyan Guan, Maoquan Chu, Yingping Zhuang and Meijin Guo
    Citation: Journal of Nanobiotechnology 2022 20:224
  13. Tumor microenvironment (TME), characterized by high glutathione (GSH), high hydrogen peroxide (H2O2) and acidic pH levels, is favorable for the growth, invasion and metastasis of cancer cells. Taking advantage of...

    Authors: Ruiyi Zhang, Teng Liu, Wanzhen Li, Zhiyuan Ma, Pei Pei, Weiwei Zhang, Kai Yang and Yugui Tao
    Citation: Journal of Nanobiotechnology 2022 20:223
  14. Osteoarthritis (OA) is a common degenerative joint disease that can lead to disability. Blocking the complex malignant feedback loop system dominated by oxidative stress and pro-inflammatory factors is the key...

    Authors: Chunrong Zhu, Shangcong Han, Xianhu Zeng, Chunxiao Zhu, Yuji Pu and Yong Sun
    Citation: Journal of Nanobiotechnology 2022 20:221
  15. MicroRNA (miRNA) plays vital roles in the regulation of both plant architecture and stress resistance through cleavage or translation inhibition of the target messenger RNAs (mRNAs). However, miRNA-induced gen...

    Authors: Jia Yang, Shuo Yan, Shipeng Xie, Meizhen Yin, Jie Shen, Zhaohu Li, Yuyi Zhou and Liusheng Duan
    Citation: Journal of Nanobiotechnology 2022 20:219
  16. Acute myocardial infarction (MI) induces a sterile inflammatory response that may result in poor cardiac remodeling and dysfunction. Despite the progress in anti-cytokine biologics, anti-inflammation therapy o...

    Authors: Jing Chen, Yanan Song, Qiaozi Wang, Qiyu Li, Haipeng Tan, Jinfeng Gao, Ning Zhang, Xueyi Weng, Dili Sun, Wusiman Yakufu, Zhengmin Wang, Juying Qian, Zhiqing Pang, Zheyong Huang and Junbo Ge
    Citation: Journal of Nanobiotechnology 2022 20:218
  17. Designing new oxygenation nanomaterials by oxygen-generating or oxygen-carrying strategies in hypoxia-associated anti-tumor therapy is a high priority target yet challenge. In this work, we fabricated a nanopl...

    Authors: Wenyao Duan, Bo Li, Wen Zhang, Jiaqi Li, Xin Yao, Yupeng Tian, Jun Zheng and Dandan Li
    Citation: Journal of Nanobiotechnology 2022 20:217
  18. Blockade of programmed cell death 1 ligand (PD-L1) has been used to treat triple-negative breast cancer (TNBC), and various strategies are under investigation to improve the treatment response rate. Inhibition...

    Authors: Yuxia Tang, Siqi Wang, Yang Li, Chen Yuan, Jie Zhang, Ziqing Xu, Yongzhi Hu, Haibin Shi and Shouju Wang
    Citation: Journal of Nanobiotechnology 2022 20:216
  19. Despite attracting increasing attention in clinic, non-invasive high-intensity focused ultrasound (HIFU) surgery still commonly suffers from tumor recurrence and even matastasis due to the generation of thermo...

    Authors: Haitao Wu, Hu Zhou, Wenjie Zhang, Ping Jin, Qianqian Shi, Zhaohua Miao, Hua Wang and Zhengbao Zha
    Citation: Journal of Nanobiotechnology 2022 20:215
  20. Immunotherapy has gradually emerged as the most promising anticancer therapy. In addition to conventional anti-PD-1/PD-L1 therapy, anti-CTLA-4 therapy, CAR-T therapy, etc., immunotherapy can also be induced by...

    Authors: Yinan Ding, Luhong Wang, Han Li, Fengqin Miao, Zhiyuan Zhang, Chunmei Hu, Weiping Yu, Qiusha Tang and Guoliang Shao
    Citation: Journal of Nanobiotechnology 2022 20:214
  21. Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease with pathophysiological characteristics of transforming growth factor-β (TGF-β), and reactive oxygen species (ROS)-induced excessive fibrob...

    Authors: Junzhao Liu, Zuohong Wu, Yadong Liu, Zhu Zhan, Liping Yang, Can Wang, Qinqin Jiang, Haitao Ran, Pan Li and Zhigang Wang
    Citation: Journal of Nanobiotechnology 2022 20:213
  22. A multifunctional nanoplatform with core–shell structure was constructed in one-pot for the synergistic photothermal, photodynamic, and chemotherapy against breast cancer. In the presence of gambogic acid (GA)...

    Authors: Rong-Tian Li, Yi-Dan Zhu, Wen-Ya Li, Ying-Ke Hou, Yi-Ming Zou, Ying-Hua Zhao, Quan Zou, Wen-Hua Zhang and Jin-Xiang Chen
    Citation: Journal of Nanobiotechnology 2022 20:212
  23. Injectable hydrogels have great promise in the treatment of myocardial infarction (MI); however, the lack of electromechanical coupling of the hydrogel to the host myocardial tissue and the inability to monito...

    Authors: Ke Zhu, Dawei Jiang, Kun Wang, Danzha Zheng, Ziyang Zhu, Fuqiang Shao, Ruijie Qian, Xiaoli Lan and Chunxia Qin
    Citation: Journal of Nanobiotechnology 2022 20:211
  24. A sort of composite hydrogel with good biocompatibility, suppleness, high conductivity, and anti-inflammatory activity based on polyvinyl alcohol (PVA) and molybdenum sulfide/graphene oxide (MoS2/GO) nanomaterial...

    Authors: Lingling Chen, Wanshun Wang, Zefeng Lin, Yao Lu, Hu Chen, Binglin Li, Zhan Li, Hong Xia, Lihua Li and Tao Zhang
    Citation: Journal of Nanobiotechnology 2022 20:210
  25. Multidrug resistance is still a major obstacle to cancer treatment. The most studies are to inhibit the activity of the drug transporter P-glycoprotein (P-gp), but the effect is not ideal. Herein, a nanosystem...

    Authors: Bin Du, Mei Zheng, Huizhen Ma, Jingshu Huang, Qingqing Jiao, Yimeng Bai, Mengmeng Zhao and Jie Zhou
    Citation: Journal of Nanobiotechnology 2022 20:209
  26. Pancreatic ductal adenocarcinoma (PDAC) interacts closely with the tumor microenvironment (TME). The TME is remodeled by crosstalk between pancreatic cancer cells and stromal cells, and is critical for cancer ...

    Authors: Ying Li, Wenjing Zhao, Yanli Wang, Haiyan Wang and Shanglong Liu
    Citation: Journal of Nanobiotechnology 2022 20:208
  27. As a typical class of crystalline porous materials, metal–organic framework possesses unique features including versatile functionality, structural and compositional tunability. After being reduced to two-dime...

    Authors: Weiqi Wang, Yuting Yu, Yilan Jin, Xiao Liu, Min Shang, Xiaohua Zheng, Tingting Liu and Zhigang Xie
    Citation: Journal of Nanobiotechnology 2022 20:207
  28. Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by diffuse inflammation of the colonic mucosa and a relapsing and remitting course. The current therapeutics are only modestly effec...

    Authors: Cui Liu, Xiangji Yan, Yujie Zhang, Mei Yang, Yana Ma, Yuanyuan Zhang, Qiuran Xu, Kangsheng Tu and Mingzhen Zhang
    Citation: Journal of Nanobiotechnology 2022 20:206
  29. The reactive oxygen species (ROS) and inflammation, a critical contributor to tissue damage, is well-known to be associated with various disease. The kidney is susceptible to hypoxia and vulnerable to ROS. Thu...

    Authors: Hong Sang Choi, Ansuja Pulickal Mathew, Saji Uthaman, Arathy Vasukutty, In Jin Kim, Sang Heon Suh, Chang Seong Kim, Seong Kwon Ma, Sontyana Adonijah Graham, Soo Wan Kim, In-Kyu Park and Eun Hui Bae
    Citation: Journal of Nanobiotechnology 2022 20:205
  30. Glypican-3 (GPC3), a membrane-bound heparan sulfate proteoglycan, is a biomarker of hepatocellular carcinoma (HCC) progression. Aptamers specifically binding to target biomolecules have recently emerged as cli...

    Authors: Woo-Ri Shin, Dae-Young Park, Ji Hun Kim, Jin-Pyo Lee, Nguyen Quang Thai, In-Hwan Oh, Simranjeet Singh Sekhon, Wooil Choi, Sung Yeon Kim, Byung-Kwan Cho, Sun Chang Kim, Jiho Min, Ji-Young Ahn and Yang-Hoon Kim
    Citation: Journal of Nanobiotechnology 2022 20:204
  31. Photodynamic therapy (PDT) is a promising antitumor strategy with fewer adverse effects and higher selectivity than conventional therapies. Recently, a series of reports have suggested that PDT induced by Cere...

    Authors: Ruijie Qian, Kun Wang, Yawen Guo, Hongyan Li, Ziyang Zhu, Xiaojuan Huang, Chengpeng Gong, Yu Gao, Rong Guo, Biao Yang, Chenyang Wang, Dawei Jiang, Xiaoli Lan, Rui An and Zairong Gao
    Citation: Journal of Nanobiotechnology 2022 20:203
  32. As a non-invasive innovative diagnosis platform, advanced flexible contact lenses can dynamically monitor vital ocular indicators, spot abnormalities and provide biofeedback guidance for real-time diagnosis an...

    Authors: Maowen Xie, Guang Yao, Tianyao Zhang, Qian Wang, Xiaoyi Mo, Qiwei Dong, Wenhao Lou, Fang Lu, Taisong Pan, Min Gao, Dawei Jiang, Kangning Zhao and Yuan Lin
    Citation: Journal of Nanobiotechnology 2022 20:202
  33. Chronic wounds represent a major challenge to the present healthcare system. In recent decades, many topical therapies have been investigated for the treatment of chronic wounds, including different types of w...

    Authors: Ke Jian, Chenghao Yang, Tingting Li, Xia Wu, Jun Shen, Jiaying Wei, Zhimou Yang, Dan Yuan, Mingyi Zhao and Junfeng Shi
    Citation: Journal of Nanobiotechnology 2022 20:201
  34. Authors: Changchang Jia, Fan Zhang, Jiamei Lin, Liwen Feng, Tiantian Wang, Yuan Feng, Feng Yuan, Yang Mai, Xiaowei Zeng and Qi Zhang
    Citation: Journal of Nanobiotechnology 2022 20:200

    The original article was published in Journal of Nanobiotechnology 2022 20:90

  35. Ferroptosis holds promise as a potential tumor therapy by programming cell death with a hallmark of reactive oxygen species (ROS)-induced lipid peroxidation. However, vigorous energy metabolism may assist tumo...

    Authors: Yanqiu Wang, Jie Chen, Jianxiu Lu, Juqun Xi, Zhilong Xu, Lei Fan, Hua Dai and Lizeng Gao
    Citation: Journal of Nanobiotechnology 2022 20:199
  36. Neural stem cells (NSCs) have the ability to generate a variety of functional neural cell types and have a high potential for neuronal cell regeneration and recovery. Thus, they been recognized as the best sou...

    Authors: Eun Ji Lee, Yoori Choi, Hong J. Lee, Do Won Hwang and Dong Soo Lee
    Citation: Journal of Nanobiotechnology 2022 20:198
  37. By 2050, the world population will increase to 10 billion which urged global demand for food production to double. Plant disease and land drought will make the situation more dire, and safer and environment-fr...

    Authors: Jianfeng Du, Baoyou Liu, Tianfeng Zhao, Xinning Xu, Han Lin, Yatai Ji, Yue Li, Zhiwei Li, Chongchong Lu, Pengan Li, Haipeng Zhao, Yang Li, Ziyi Yin and Xinhua Ding
    Citation: Journal of Nanobiotechnology 2022 20:197
  38. Steatotic livers tolerate ischemia–reperfusion injury (IRI) poorly, increasing the risk of organ dysfunction. Ferroptosis is considered the initiating factor of organ IRI. Heme oxygenase oxygen-1 (HO-1)-modifi...

    Authors: Longlong Wu, Xuan Tian, Huaiwen Zuo, Weiping Zheng, Xiang Li, Mengshu Yuan, Xiaorong Tian and Hongli Song
    Citation: Journal of Nanobiotechnology 2022 20:196
  39. The rapid spread of infectious bacteria has brought great challenges to public health. It is imperative to explore effective and environment-friendly antibacterial modality to defeat antibiotic-resistant bacte...

    Authors: Yangzi Yang, Chengwei Wang, Ning Wang, Jiaxin Li, Yingchun Zhu, Jiantao Zai, Jingke Fu and Yongqiang Hao
    Citation: Journal of Nanobiotechnology 2022 20:195
  40. As a natural product with various biological activities, triptolide (TP) has been reported in anti-inflammatory, anti-tumor and anti-autoimmune studies. However, the narrow therapeutic window, poor water solub...

    Authors: Rui Sun, Jingyue Dai, Mingjian Ling, Ling Yu, Zhiqiang Yu and Longguang Tang
    Citation: Journal of Nanobiotechnology 2022 20:194
  41. Different from Fe ions in Fenton reaction, Mn ions can function both as catalyst for chemodynamic therapy and immune adjuvant for antitumor immune responses. In Mn-mediated Fenton-like reaction, bicarbonate (

    Authors: Yushuo Feng, Yaqing Liu, Xiaoqian Ma, Lihua Xu, Dandan Ding, Lei Chen, Zongzhang Wang, Ruixue Qin, Wenjing Sun and Hongmin Chen
    Citation: Journal of Nanobiotechnology 2022 20:193
  42. Authors: Shibo Xu, Linna Chang, Yanan Hu, Xingjun Zhao, Shuocheng Huang, Zhenhua Chen, Xiuli Ren and Xifan Mei
    Citation: Journal of Nanobiotechnology 2022 20:192

    The original article was published in Journal of Nanobiotechnology 2021 19:362

  43. Nanoplastics have been recently found widely distributed in our natural environment where ubiquitously bacteria are major participants in various material cycles. Understanding how nanoplastics interact with b...

    Authors: Shang Dai, Rui Ye, Jianxiang Huang, Binqiang Wang, Zhenming Xie, Xinwen Ou, Ning Yu, Cheng Huang, Yuejin Hua, Ruhong Zhou and Bing Tian
    Citation: Journal of Nanobiotechnology 2022 20:191
  44. Neoantigens are considered ideal targets for immunotherapy, especially tumor vaccine, because of their strong specificity and immunogenicity. Here, we developed a neoantigen nanovaccine used liposomes with lym...

    Authors: Yanhong Chu, Lingyu Qian, Yaohua Ke, Xiaoyu Feng, Xinjie Chen, Fangcen Liu, Lixia Yu, Lianru Zhang, Yaping Tao, Rui Xu, Jia Wei, Baorui Liu and Qin Liu
    Citation: Journal of Nanobiotechnology 2022 20:190
  45. Extracellular vesicles (EVs), spherical biological vesicles, mainly contain nucleic acids, proteins, lipids and metabolites for biological information transfer between cells. Microparticles (MPs), a subtype of...

    Authors: Yan Hu, Yajie Sun, Chao Wan, Xiaomeng Dai, Shuhui Wu, Pui-Chi Lo, Jing Huang, Jonathan F. Lovell, Honglin Jin and Kunyu Yang
    Citation: Journal of Nanobiotechnology 2022 20:189
  46. Calcium ions (Ca2+) participates in various intracellular signal cascades and especially plays a key role in pathways relevant to cancer cells. Mitochondrial metabolism stimulated by calcium overload can trigger ...

    Authors: Ying Zhou, Shisong Jing, Sainan Liu, Xizhong Shen, Lihan Cai, Changfeng Zhu, Yicheng Zhao and Maolin Pang
    Citation: Journal of Nanobiotechnology 2022 20:188
  47. Non-redundant properties such as hypoxia and acidosis promote tumor metabolic adaptation and limit anti-cancer therapies. The key to the adaptation of tumor cells to hypoxia is the transcriptional and stable e...

    Authors: Jie Liu, Xiaochun Hu, Lei Feng, Yun Lin, Shujing Liang, Zhounan Zhu, Shuo Shi and Chunyan Dong
    Citation: Journal of Nanobiotechnology 2022 20:187
  48. Sonodynamic therapy (SDT) is a burgeoning modality for cancer therapy owing to its high tissue-penetrating capability, controllability and safety. Whereas, the undesirable reactive oxygen species (ROS) yield o...

    Authors: Xiaohui Qiao, Liyun Xue, Hui Huang, Xinyue Dai, Yu Chen and Hong Ding
    Citation: Journal of Nanobiotechnology 2022 20:186
  49. Albumin-biomineralized copper sulfide nanoparticles (Cu2−xS NPs) have attracted much attention as an emerging phototheranostic agent due to their advantages of facile preparation method and high biocompatibility....

    Authors: Ya-Nan Xia, He Zu, Haoxiang Guo, Tianyan Jiang, Siqi Yang, Huan Yu, Shaodian Zhang, Heng Ding, Xiaoyu Li, Yangyun Wang, Yong Wang and Leshuai W. Zhang
    Citation: Journal of Nanobiotechnology 2022 20:185
  50. Effective and accurate screening of oncological biomarkers in peripheral blood circulation plays an increasingly vital role in diagnosis and prognosis. High-sensitivity assays can effectively aid clinical deci...

    Authors: Mengyao Liu, Yonghong Li, Wei Xing, Yuqin Zhang, Xi Xie, Jiadong Pang, Fangjian Zhou and Jiang Yang
    Citation: Journal of Nanobiotechnology 2022 20:184

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