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  1. Content type: Review

    Atomic force microscopy (AFM) allows for nanometer-scale investigation of cells and molecules. Recent advances have enabled its application in cancer research and diagnosis. The physicochemical properties of l...

    Authors: Xiangying Deng, Fang Xiong, Xiayu Li, Bo Xiang, Zheng Li, Xu Wu, Can Guo, Xiaoling Li, Yong Li, Guiyuan Li, Wei Xiong and Zhaoyang Zeng

    Citation: Journal of Nanobiotechnology 2018 16:102

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  2. Content type: Research

    We introduce a self-assembling polypeptide-based nanotube system having the ability to specifically target cancer cells. The nanotubes target the cancer cell surface through integrin engagement with the help o...

    Authors: Gitanjali Asampille, Brijesh Kumar Verma, Monalisa Swain, Abhijith Shettar, Steven A. Rosenzweig, Paturu Kondaiah and Hanudatta S. Atreya

    Citation: Journal of Nanobiotechnology 2018 16:101

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  3. Content type: Research

    Particokinetic models are important to predict the effective cellular dose, which is key to understanding the interactions of particles with biological systems. For the reliable establishment of dose–response ...

    Authors: Thomas Kowoll, Susanne Fritsch-Decker, Silvia Diabaté, Gerd Ulrich Nienhaus, Dagmar Gerthsen and Carsten Weiss

    Citation: Journal of Nanobiotechnology 2018 16:100

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  4. Content type: Research

    Cancer stem cells (CSCs) are highly proliferative and tumorigenic, which contributes to chemotherapy resistance and tumor occurrence. CSCs specific therapy may achieve excellent therapeutic effects, especially...

    Authors: Yuanyuan Li, Sanjun Shi, Yue Ming, Linli Wang, Chenwen Li, Minghe Luo, Ziwei Li, Bin Li and Jianhong Chen

    Citation: Journal of Nanobiotechnology 2018 16:99

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  5. Content type: Research

    Sustained drug delivery is a large unmet clinical need in glaucoma. Here, we incorporated a Myocardin-Related Transcription Factor/Serum Response Factor inhibitor, CCG-222740, into slow release large unilamell...

    Authors: Aristides D. Tagalakis, Shivam Madaan, Scott D. Larsen, Richard R. Neubig, Peng T. Khaw, Ian Rodrigues, Saurabh Goyal, Kin Sheng Lim and Cynthia Yu-Wai-Man

    Citation: Journal of Nanobiotechnology 2018 16:97

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  6. Content type: Research

    In orthopedic surgery, implant-associated infections are still a major problem. For the improvement of the selective therapy in the infection area, magnetic nanoparticles as drug carriers are promising when us...

    Authors: Hilke Catherina Janßen, Dawid Peter Warwas, David Dahlhaus, Jessica Meißner, Piriya Taptimthong, Manfred Kietzmann, Peter Behrens, Janin Reifenrath and Nina Angrisani

    Citation: Journal of Nanobiotechnology 2018 16:96

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  7. Content type: Review

    The need and desire to understand the environment, especially the quality of one’s local water and air, has continued to expand with the emergence of the digital age. The bottleneck in understanding the enviro...

    Authors: Marjorie R. Willner and Peter J. Vikesland

    Citation: Journal of Nanobiotechnology 2018 16:95

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  8. Content type: Research

    Modern agricultural practises rely on surfactant-based spray applications to eliminate weeds in crops. The wide spread and indiscriminate use of surfactants may result in a number of deleterious effects that a...

    Authors: Pavani P. Nadiminti, Qingtao Liu, Lavanya K. Vanjari, Yao D. Dong, Ben J. Boyd and David M. Cahill

    Citation: Journal of Nanobiotechnology 2018 16:94

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  9. Content type: Research

    Given the great benefits of artificial enzymes, a simple approach is proposed via assembling of Ni2+ with hemin for synthesis of Ni-hemin metal–organic-frameworks (Ni-hemin MOFs) mimic enzyme. The formation of th...

    Authors: Negar Alizadeh, Abdollah Salimi, Rahman Hallaj, Fardin Fathi and Farzad Soleimani

    Citation: Journal of Nanobiotechnology 2018 16:93

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  10. Content type: Research

    Atherosclerosis, a major source of cardiovascular disease, is asymptomatic for decades until the activation of thrombosis and the rupture of enlarged plaques, resulting in acute coronary syndromes and sudden c...

    Authors: Christopher Poon, Juan Gallo, Johan Joo, Timothy Chang, Manuel Bañobre-López and Eun Ji Chung

    Citation: Journal of Nanobiotechnology 2018 16:92

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  11. Content type: Research

    Microdialysis is promising technique for dynamic microbiochemical sampling from tissues. However, the application of typical aqueous perfusates to liposoluble substances is limited. In this study, a novel micr...

    Authors: Yong-Tai Zhang, Zhi Wang, Li-Na Shen, Yan-Yan Li, Ze-Hui He, Qing Xia and Nian-Ping Feng

    Citation: Journal of Nanobiotechnology 2018 16:91

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  12. Content type: Research

    In the last decade, the biosynthesis of metal nanoparticles using organisms have received more and more considerations. However, the complex composition of organisms adds up to a great barrier for the characte...

    Authors: Shichao Wu, Xiangrui Yang, Fanghong Luo, Ting Wu, Peilan Xu, Mingyuan Zou and Jianghua Yan

    Citation: Journal of Nanobiotechnology 2018 16:90

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  13. Content type: Research

    Developing an ideal wound dressing that meets the multiple demands of good biocompatibility, an appropriate porous structure, superior mechanical property and excellent antibacterial activity against drug-resi...

    Authors: Menglong Liu, Tengfei Liu, Xiwei Chen, Jiacai Yang, Jun Deng, Weifeng He, Xiaorong Zhang, Qiang Lei, Xiaohong Hu, Gaoxing Luo and Jun Wu

    Citation: Journal of Nanobiotechnology 2018 16:89

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  14. Content type: Review

    Oxidative stress (OS) and nitrative stress (NS) accompany many diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Antioxidants have been proposed to counteract OS/NS in these diseases. ...

    Authors: Izabela Sadowska-Bartosz and Grzegorz Bartosz

    Citation: Journal of Nanobiotechnology 2018 16:87

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  15. Content type: Research

    We have previously shown that intraperitoneal injection of gold nanoparticles (AuNPs, 20–30 nm) into mice, decreases high-fat diet (HFD) induced weight gain and glucose intolerance, via suppression of inflamma...

    Authors: Hui Chen, Jane P. M. Ng, David P. Bishop, Bruce K. Milthorpe and Stella M. Valenzuela

    Citation: Journal of Nanobiotechnology 2018 16:88

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  16. Content type: Research

    Gold nanoparticles (AuNPs) are attracting interest as potential therapeutic agents to treat inflammatory diseases, but their anti-inflammatory mechanism of action is not clear yet. In addition, the effect of o...

    Authors: Suqin Zhu, Xiumei Jiang, Mary D. Boudreau, Guangxin Feng, Yu Miao, Shiyuan Dong, Haohao Wu, Mingyong Zeng and Jun-Jie Yin

    Citation: Journal of Nanobiotechnology 2018 16:86

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  17. Content type: Research

    The biomedical use of nanosized materials is rapidly gaining interest, which drives the quest to elucidate the behavior of nanoparticles (NPs) in a biological environment. Apart from causing direct cell death,...

    Authors: Bella B. Manshian, Suman Pokhrel, Lutz Mädler and Stefaan J. Soenen

    Citation: Journal of Nanobiotechnology 2018 16:85

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  18. Content type: Review

    In materials science, “green” synthesis has gained extensive attention as a reliable, sustainable, and eco-friendly protocol for synthesizing a wide range of materials/nanomaterials including metal/metal oxid...

    Authors: Jagpreet Singh, Tanushree Dutta, Ki-Hyun Kim, Mohit Rawat, Pallabi Samddar and Pawan Kumar

    Citation: Journal of Nanobiotechnology 2018 16:84

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  19. Content type: Research

    The continuously growing human exposure to combustion-derived particles (CDPs) drives in depth investigation of the involved complex toxicological mechanisms of those particles. The current study evaluated the...

    Authors: Hannelore Bové, Jens Devoght, Leentje Rasking, Martijn Peters, Eli Slenders, Maarten Roeffaers, Alvaro Jorge-Peñas, Hans Van Oosterwyck and Marcel Ameloot

    Citation: Journal of Nanobiotechnology 2018 16:82

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  20. Content type: Research

    In order to explore the possibility of treating breast cancer by local photo-therapy, a photothermal agents loaded in situ hydrogel was established. In detail, The Cu2MnS2 nanoplates were prepared by one-pot synt...

    Authors: Ji-jun Fu, Ming-yue Chen, Jie-xia Li, Jun-hua Zhou, Sheng-nan Xie, Ping Yuan, Bo Tang and Cheng-cheng Liu

    Citation: Journal of Nanobiotechnology 2018 16:83

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  21. Content type: Review

    Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studi...

    Authors: Edwin J. Bunggulawa, Wei Wang, Tieying Yin, Nan Wang, Colm Durkan, Yazhou Wang and Guixue Wang

    Citation: Journal of Nanobiotechnology 2018 16:81

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  22. Content type: Research

    Engineered inorganic nanoparticles (NPs) are essential components in the development of nanotechnologies. For applications in nanomedicine, particles need to be functionalized to ensure a good dispersibility i...

    Authors: Muhammad Raisul Abedin, Siddesh Umapathi, Harika Mahendrakar, Tunyaboon Laemthong, Holly Coleman, Denise Muchangi, Santimukul Santra, Manashi Nath and Sutapa Barua

    Citation: Journal of Nanobiotechnology 2018 16:80

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  23. Content type: Research

    Gold nanoparticles (AuNPs) are promising candidates to design the next generation NP-based drug formulations specifically treating maternal, fetal or placental complications with reduced side effects. Profound...

    Authors: Leonie Aengenheister, Dörthe Dietrich, Amin Sadeghpour, Pius Manser, Liliane Diener, Adrian Wichser, Uwe Karst, Peter Wick and Tina Buerki-Thurnherr

    Citation: Journal of Nanobiotechnology 2018 16:79

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  24. Content type: Research

    Differentiation of telomere length is of vital importance because telomere length is closely related with several deadly diseases such as cancer. Additionally, G-quadruplex and i-motif formation in telomeric D...

    Authors: Shuai Wang, Fei Qu, Wenli Han and Jinmao You

    Citation: Journal of Nanobiotechnology 2018 16:78

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  25. Content type: Research

    Effectiveness of chemotherapy for treating glioblastoma (GBM) brain tumors is hampered by the blood–brain barrier which limits the entry into the brain of most drugs from the blood. To bypass this barrier, con...

    Authors: Minghan Shi, Malathi Anantha, Mohamed Wehbe, Marcel B. Bally, David Fortin, Laurent-Olivier Roy, Gabriel Charest, Maxime Richer, Benoit Paquette and Léon Sanche

    Citation: Journal of Nanobiotechnology 2018 16:77

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  26. Content type: Research

    Recently, we found that berberine (BBR) exerts anti-acute myeloid leukemia activity, particularly toward high-risk and relapsed/refractory acute myeloid leukemia MV4-11 cells in vitro. However, the poor water ...

    Authors: Jieping Li, Li Yang, Rui Shen, Li Gong, Zhiqiang Tian, Huarong Qiu, Zhe Shi, Lichen Gao, Hongwu Sun and Guangsen Zhang

    Citation: Journal of Nanobiotechnology 2018 16:76

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  27. Content type: Review

    Graphene’s unique physical structure, as well as its chemical and electrical properties, make it ideal for use in sensor technologies. In the past years, novel sensing platforms have been proposed with pristin...

    Authors: Janire Peña-Bahamonde, Hang N. Nguyen, Sofia K. Fanourakis and Debora F. Rodrigues

    Citation: Journal of Nanobiotechnology 2018 16:75

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  28. Content type: Review

    With the improvement of nanotechnology and nanomaterials, redox-responsive delivery systems have been studied extensively in some critical areas, especially in the field of biomedicine. The system constructed...

    Authors: Xiaoshuang Guo, Yuan Cheng, Xiaotian Zhao, Yanli Luo, Jianjun Chen and Wei-En Yuan

    Citation: Journal of Nanobiotechnology 2018 16:74

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  29. Content type: Research

    Galectin-3 (Gal-3) is a promising target in cancer therapy with a high therapeutic potential due to its abundant localization within the tumor tissue and its involvement in tumor development and proliferation....

    Authors: P. Bojarová, M. R. Tavares, D. Laaf, L. Bumba, L. Petrásková, R. Konefał, M. Bláhová, H. Pelantová, L. Elling, T. Etrych, P. Chytil and V. Křen

    Citation: Journal of Nanobiotechnology 2018 16:73

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  30. Content type: Review

    Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic ag...

    Authors: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Estefania Vangelie Ramos Campos, Maria del Pilar Rodriguez-Torres, Laura Susana Acosta-Torres, Luis Armando Diaz-Torres, Renato Grillo, Mallappa Kumara Swamy, Shivesh Sharma, Solomon Habtemariam and Han-Seung Shin

    Citation: Journal of Nanobiotechnology 2018 16:71

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  31. Content type: Research

    Messenger RNA (mRNA) has gained remarkable attention as an alternative to DNA-based therapies in biomedical research. A variety of biodegradable nanoparticles (NPs) has been developed including lipid-based and...

    Authors: Hanzey Yasar, Alexander Biehl, Chiara De Rossi, Marcus Koch, Xabi Murgia, Brigitta Loretz and Claus-Michael Lehr

    Citation: Journal of Nanobiotechnology 2018 16:72

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  32. Content type: Research

    Upon ingestion, nanoparticles can interact with the intestinal epithelial barrier potentially resulting in systemic uptake of nanoparticles. Nanoparticle properties have been described to influence the protein...

    Authors: Ashraf Abdelkhaliq, Meike van der Zande, Ans Punt, Richard Helsdingen, Sjef Boeren, Jacques J. M. Vervoort, Ivonne M. C. M. Rietjens and Hans Bouwmeester

    Citation: Journal of Nanobiotechnology 2018 16:70

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  33. Content type: Research

    Porphyromonas gingivalis adherence to oral streptococci is a key point in the pathogenesis of periodontal diseases (Honda in Cell Host Microbe 10:423–425, 2011). Previous work in our groups has shown that a regio...

    Authors: Mohamed Y. Mahmoud, Donald R. Demuth and Jill M. Steinbach-Rankins

    Citation: Journal of Nanobiotechnology 2018 16:69

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  34. Content type: Research

    In recent years, nanoparticles (NPs) including nanostructured lipid carries (NLC) and solid lipid nanoparticles (SLN) captured an increasing amount of attention in the field of transdermal drug delivery system...

    Authors: Yongwei Gu, Meng Yang, Xiaomeng Tang, Ting Wang, Dishun Yang, Guangxi Zhai and Jiyong Liu

    Citation: Journal of Nanobiotechnology 2018 16:68

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  35. Content type: Research

    Although assemblies of hydrophobic-modified bacitracin A with PLGA (Nano-BAPLGA) have demonstrated promising antibacterial activities against both Gram-positive and Gram-negative bacteria, the desirable antibacte...

    Authors: Wei Hong, Lipeng Liu, Yining Zhao, Yinghui Liu, Dexian Zhang and Mingchun Liu

    Citation: Journal of Nanobiotechnology 2018 16:66

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  36. Content type: Short Communication

    Intracellular protein and proteomic studies using mass spectrometry, imaging microscopy, flow cytometry, or western blotting techniques require genetic manipulation, cell permeabilization, and/or cell lysis. W...

    Authors: Elaheh Shekaramiz, Rupak Doshi and H. Kumar Wickramasinghe

    Citation: Journal of Nanobiotechnology 2018 16:67

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  37. Content type: Research

    Due to the high transfer ability of cancer cell, cancer has been regarded as a world-wide high mortality disease. Quantitative analysis of circulating tumor cells (CTCs) can provide some valuable clinical info...

    Authors: Xuan Wu, Tingyu Xiao, Zhang Luo, Rongxiang He, Yiping Cao, Zhenzhong Guo, Weiying Zhang and Yong Chen

    Citation: Journal of Nanobiotechnology 2018 16:65

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  38. Content type: Research

    Non-alcoholic fatty liver disease (NAFLD) is a chronic disease that causes excessive hepatic lipid accumulation. Reducing hepatic lipid deposition is a key issue in treatment and inhibition of NAFLD evolution....

    Authors: Jun Liang, Ying Liu, Jinguang Liu, Zhe Li, Qiangyuan Fan, Zifei Jiang, Fei Yan, Zhi Wang, Peiwen Huang and Nianping Feng

    Citation: Journal of Nanobiotechnology 2018 16:64

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  39. Content type: Research

    Extracellular vesicles (EVs) and exosomes are nano-sized, membrane-bound vesicles shed by most eukaryotic cells studied to date. EVs play key signaling roles in cellular development, cancer metastasis, immune ...

    Authors: Travis J. Antes, Ryan C. Middleton, Kristin M. Luther, Takeshi Ijichi, Kiel A. Peck, Weixin Jane Liu, Jackie Valle, Antonio K. Echavez and Eduardo Marbán

    Citation: Journal of Nanobiotechnology 2018 16:61

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  40. Content type: Research

    Epidermal growth factor (EGF) can promote cell proliferation as well as migration, which is feasible in tissue wound healing. Oil bodies have been exploited as an important platform to produce exogenous protei...

    Authors: Weidong Qiang, Tingting Zhou, Xinxin Lan, Xiaomei Zhang, Yongxin Guo, Muhammad Noman, Linna Du, Jie Zheng, Wenqing Li, Haoyang Li, Yubin Lu, Hongyu Wang, Lili Guan, Linbo Zhang, Xiaokun Li, Jing Yang…

    Citation: Journal of Nanobiotechnology 2018 16:62

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  41. Content type: Research

    Stable and non-toxic fluorescent markers are gaining attention in molecular diagnostics as powerful tools for enabling long and reliable biological studies. Such markers should not only have a long half-life u...

    Authors: Francisco Morales-Zavala, Nathalie Casanova-Morales, Raúl B. Gonzalez, América Chandía-Cristi, Lisbell D. Estrada, Ignacio Alvizú, Victor Waselowski, Fanny Guzman, Simón Guerrero, Marisol Oyarzún-Olave, Cristian Rebolledo, Enrique Rodriguez, Julien Armijo, Heman Bhuyan, Mario Favre, Alejandra R. Alvarez…

    Citation: Journal of Nanobiotechnology 2018 16:60

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  42. Content type: Research

    Various nanocarriers have been used to deliver subunit vaccines specifically to dendritic cells (DCs) for the improvement of immunogenicity. However, due to their insufficient DC priming ability, these vaccine...

    Authors: Hidenori Matsuo, Masaharu Somiya, Masumi Iijima, Takeshi Arakawa and Shun’ichi Kuroda

    Citation: Journal of Nanobiotechnology 2018 16:59

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  43. Content type: Research

    The transcription factor NF-kB plays an important role in the pathogenesis of rheumatoid arthritis (RA). Effective treatment of RA is hindered due to the lack of specificity of small molecules in the inflamed ...

    Authors: Weifeng Duan and Huan Li

    Citation: Journal of Nanobiotechnology 2018 16:58

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  44. Content type: Research

    Matrix-metalloproteinases, which are overexpressed in many types of cancer, can be applied to improve the bioavailability of chemotherapeutic drugs and guide therapeutic targeting. Thus, we aimed to develop en...

    Authors: Fangyuan Guo, Jiangqing Wu, Wenchao Wu, Dongxue Huang, Qinying Yan, Qingliang Yang, Ying Gao and Gensheng Yang

    Citation: Journal of Nanobiotechnology 2018 16:57

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  45. Content type: Research

    Chemotherapeutic agents (anti-cancer drugs) are small cytostatic or cytotoxic molecules that often bind to double-stranded DNA (dsDNA) resulting in modifications of their structural and nanomechanical properti...

    Authors: Dennis Kreft, Ying Wang, Michael Rattay, Katja Toensing and Dario Anselmetti

    Citation: Journal of Nanobiotechnology 2018 16:56

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  46. Content type: Research

    Autophagy regulation through exogenous materials has aroused intensive attention to develop treatment protocols according to diverse human diseases. However, to the best of our knowledge, few examples have bee...

    Authors: Long Yuan, Fan Zhang, Xiaowei Qi, Yongjun Yang, Chang Yan, Jun Jiang and Jun Deng

    Citation: Journal of Nanobiotechnology 2018 16:55

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  47. Content type: Research

    Tumor metastasis is the primary cause of mortality in cancer patients. Migratory breast cancer cells in lymphatic and blood vessels seek new sites and form metastatic colonies in the lung and bone, and then th...

    Authors: Yanxia Qin, Kui Chen, Weihong Gu, Xinghua Dong, Ruihong Lei, Yanan Chang, Xue Bai, Shibo Xia, Li Zeng, Jiaxin Zhang, Sihan Ma, Juan Li, Shan Li and Gengmei Xing

    Citation: Journal of Nanobiotechnology 2018 16:54

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  48. Content type: Research

    Titanium dioxide (TiO2) particles are commonly used as a food additive (E171 in the EU) for its whitening and opacifying properties. However, the risk of gut barrier disruption is an increasing concern because of...

    Authors: Pauline Talbot, Joanna M. Radziwill-Bienkowska, Jasper B. J. Kamphuis, Karine Steenkeste, Sarah Bettini, Véronique Robert, Marie-Louise Noordine, Camille Mayeur, Eric Gaultier, Philippe Langella, Catherine Robbe-Masselot, Eric Houdeau, Muriel Thomas and Muriel Mercier-Bonin

    Citation: Journal of Nanobiotechnology 2018 16:53

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