Skip to main content

Articles

Page 1 of 55

  1. The glymphatic system plays an important role in the transportation of cerebrospinal fluid (CSF) and the clearance of metabolite waste in brain. However, current imaging modalities for studying the glymphatic ...

    Authors: Bin Sun, Danlan Fang, Wenzhong Li, Mengfei Li and Shoujun Zhu
    Citation: Journal of Nanobiotechnology 2024 22:200
  2. Considering the high recrudescence and the long-lasting unhealed large-sized wound that affect the aesthetics and cause dysfunction after resection of maxillofacial malignant skin tumors, a groundbreaking stra...

    Authors: Shaojie Dong, Yuwei Zhang, Yifei Zhang, Yukun Mei, Ahmadi Sina, Rui Zou and Lin Niu
    Citation: Journal of Nanobiotechnology 2024 22:199
  3. Heat shock protein 90 (HSP90) is overexpressed in numerous cancers, promotes the maturation of numerous oncoproteins and facilitates cancer cell growth. Certain HSP90 inhibitors have entered clinical trials. A...

    Authors: Lejiao Jia, Huatian Yang, Yue Liu, Ying Zhou, Guosheng Li, Qian Zhou, Yan Xu, Zhiping Huang, Feng Ye, Jingjing Ye, Anchang Liu and Chunyan Ji
    Citation: Journal of Nanobiotechnology 2024 22:198
  4. Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by synovial inflammation, causing substantial disability and reducing life quality. While macrophages are widely appreciated as a master...

    Authors: Huan Liu, Yuehong Chen, Yupeng Huang, Ling Wei, Jingjing Ran, Qianwei Li, Yunru Tian, Zhongling Luo, Leiyi Yang, Hongjiang Liu, Geng Yin and Qibing Xie
    Citation: Journal of Nanobiotechnology 2024 22:197
  5. Tumors desmoplastic microenvironments are characterized by abundant stromal cells and extracellular matrix (ECM) deposition. Cancer-associated fibroblasts (CAFs), as the most abundant of all stromal cells, pla...

    Authors: Xiaoxia Xue, Xiangpeng Wang, Mingshi Pang, Liuchunyang Yu, Jinxiu Qian, Xiaoyu Li, Meng Tian, Cheng Lu, Cheng Xiao and Yuanyan Liu
    Citation: Journal of Nanobiotechnology 2024 22:196
  6. Doxorubicin (DOX) is a chemotherapeutic agent widely used for tumor treatment. Nonetheless its clinical application is heavily limited by its cardiotoxicity. There is accumulated evidence that transplantation ...

    Authors: Huifeng Zheng, Xiaoting Liang, Baojuan Liu, Xinran Huang, Ying Shen, Fang Lin, Jiaqi Chen, Xiaoyan Gao, Haiwei He, Weifeng Li, Bei Hu, Xin Li and Yuelin Zhang
    Citation: Journal of Nanobiotechnology 2024 22:195
  7. Several studies suggest that topographical patterns influence nerve cell fate. Efforts have been made to improve nerve cell functionality through this approach, focusing on therapeutic strategies that enhance ...

    Authors: Majid Sharifi, Mohammad Kamalabadi-Farahani, Majid Salehi, Somayeh Ebrahimi-Barough and Morteza Alizadeh
    Citation: Journal of Nanobiotechnology 2024 22:194
  8. Pyroptosis, a novel type of programmed cell death (PCD), which provides a feasible therapeutic option for the treatment of tumors. However, due to the hypermethylation of the promoter, the critical protein Gas...

    Authors: Shuting Huang, Mengmeng Shang, Lu Guo, Xiao Sun, Shan Xiao, Dandan Shi, Dong Meng, Yading Zhao, Xiaoxuan Wang, Rui Liu and Jie Li
    Citation: Journal of Nanobiotechnology 2024 22:193
  9. Androgen deprivation therapy (ADT) is a crucial and effective strategy for prostate cancer, while systemic administration may cause profound side effects on normal tissues. More importantly, the ADT can easily...

    Authors: Yiming Guo, Jicheng Wu, Lefan Chen, Lujie Liu, Tianxiang Bi, Yuanwei Pan, Qian-Fang Meng, Chaoliang Wang, Lang Rao and Qi Li
    Citation: Journal of Nanobiotechnology 2024 22:192
  10. Exosomes assume a pivotal role as essential mediators of intercellular communication within tumor microenvironments. Within this context, long noncoding RNAs (LncRNAs) have been observed to be preferentially s...

    Authors: Xu Zhou, Xiaohan Kong, Jun Lu, Heng Wang, Meng Liu, Shuchao Zhao, Zhaozhi Xia, Qinggong Liu, Hongrui Sun, Xin Gao, Chaoqun Ma, Zheyu Niu, Faji Yang, Xie Song, Hengjun Gao, Shizhe Zhang…
    Citation: Journal of Nanobiotechnology 2024 22:191
  11. Acute lung injury (ALI) is generally caused by severe respiratory infection and characterized by overexuberant inflammatory responses and inefficient pathogens-containing, the two major processes wherein alveo...

    Authors: Lusha Ye, Yanan Gao, Simon Wing Fai Mok, Wucan Liao, Yazhou Wang, Changjiang Chen, Lijun Yang, Junfeng Zhang and Liyun Shi
    Citation: Journal of Nanobiotechnology 2024 22:190
  12. Although gene expression signatures offer tremendous potential in diseases diagnostic and prognostic, but massive gene expression signatures caused challenges for experimental detection and computational analy...

    Authors: Li Zhang, Qian Liu, Yongcan Guo, Luyao Tian, Kena Chen, Dan Bai, Hongyan Yu, Xiaole Han, Wang Luo, Tong Feng, Shixiong Deng and Guoming Xie
    Citation: Journal of Nanobiotechnology 2024 22:189
  13. Rheumatoid arthritis (RA) is a progressive autoimmune disease accompanied by joint swelling, cartilage erosion and bone damage. Drug therapy for RA has been restricted due to poor therapeutic effect, recurrenc...

    Authors: Yiqun Wu, Yu Ge, Zhongshi Wang, Ying Zhu, Tianli Tian, Jun Wei, Yu Jin, Yi Zhao, Qiang jia, Jun Wu and Liang Ge
    Citation: Journal of Nanobiotechnology 2024 22:188
  14. Pathological conditions linked to shear stress have been identified in hematological diseases, cardiovascular diseases, and cancer. These conditions often exhibit significantly elevated shear stress levels, su...

    Authors: Zhihang Yu, Yiqun Chen, Jingjing Li, Chang Chen, Huaxiu Lu, Siyuan Chen, Tingting Zhang, Tianruo Guo, Yonggang Zhu, Jing Jin, Sheng Yan and Huaying Chen
    Citation: Journal of Nanobiotechnology 2024 22:187
  15. Animal-derived biomaterials have been extensively employed in clinical practice owing to their compositional and structural similarities with those of human tissues and organs, exhibiting good mechanical prope...

    Authors: Xiaorong Lan, Mingdong Luo, Meiling Li, Linpeng Mu, Guangwen Li, Gong Chen, Zhoukun He and Jingang Xiao
    Citation: Journal of Nanobiotechnology 2024 22:186
  16. Rare earth nanomaterials (RE NMs), which are based on rare earth elements, have emerged as remarkable biomaterials for use in bone regeneration. The effects of RE NMs on osteogenesis, such as promoting the ost...

    Authors: Ziwei Chen, Xiaohe Zhou, Minhua Mo, Xiaowen Hu, Jia Liu and Liangjiao Chen
    Citation: Journal of Nanobiotechnology 2024 22:185
  17. Despite the advent of numerous targeted therapies in clinical practice, anthracyclines, including doxorubicin (DOX), continue to play a pivotal role in breast cancer (BC) treatment. DOX directly disrupts DNA r...

    Authors: Marta Sevieri, Francesco Andreata, Francesco Mainini, Lorena Signati, Francesca Piccotti, Marta Truffi, Arianna Bonizzi, Leopoldo Sitia, Claudia Pigliacelli, Carlo Morasso, Barbara Tagliaferri, Fabio Corsi and Serena Mazzucchelli
    Citation: Journal of Nanobiotechnology 2024 22:184
  18. The use of cells as carriers for the delivery of nanoparticles is a promising approach in anticancer therapy, mainly due to their natural properties, such as biocompatibility and non-immunogenicity. Cellular c...

    Authors: Anna Wróblewska, Bożena Szermer-Olearnik, Agnieszka Szczygieł, Katarzyna Węgierek-Ciura, Jagoda Mierzejewska, Dawid Kozień, Paulina Żeliszewska, Roksana Kruszakin, Paweł Migdał, Zbigniew Pędzich and Elżbieta Pajtasz-Piasecka
    Citation: Journal of Nanobiotechnology 2024 22:183
  19. Hydrogels are a class of highly absorbent and easily modified polymer materials suitable for use as slow-release carriers for drugs. Gene therapy is highly specific and can overcome the limitations of traditio...

    Authors: Chunyu Su, Dini Lin, Xinyu Huang, Jiayin Feng, Anqi Jin, Fangyan Wang, Qizhuang Lv, Lanjie Lei and Wenjie Pan
    Citation: Journal of Nanobiotechnology 2024 22:182
  20. Periodontitis is an inflammatory disease induced by the complex interactions between the host immune system and the microbiota of dental plaque. Oxidative stress and the inflammatory microenvironment resulting...

    Authors: Jinhong Chen, Aihua Luo, Mengmeng Xu, Yao Zhang, Zheng Wang, Shuang Yu, Li Zhu, Wei Wu and Deqin Yang
    Citation: Journal of Nanobiotechnology 2024 22:181
  21. To address the limitations of traditional photothermal therapy (PTT)/ photodynamic therapy (PDT) and real-time cancer metastasis detection, a pH-responsive nanoplatform (NP) with dual-modality imaging capabili...

    Authors: Mujie Yuan, Zeyu Han, Yan Li, Xin Zhan, Yong Sun, Bin He, Yan Liang, Kui Luo and Fan Li
    Citation: Journal of Nanobiotechnology 2024 22:180
  22. We report on the fabrication of mesoporous silicon dioxide coated Haliclona sp. spicules (mSHS) to enhance the delivery of the insoluble photosensitizer protoporphyrin IX (PpIX) into deep skin layers and mediate ...

    Authors: Xuejiao Liang, Jialiang Zhang, Chi Zhang, Haojie Zhai, Ping Yang and Ming Chen
    Citation: Journal of Nanobiotechnology 2024 22:179
  23. Clearance of apoptotic cells by efferocytosis is crucial for prevention of atherosclerosis progress, and impaired efferocytosis contributes to the aggravated atherosclerosis.

    Authors: Shuo Qiu, Jiahan Liu, Jianmei Chen, Yangni Li, Te Bu, Zhelong Li, Liang Zhang, Wenqi Sun, Tian Zhou, Wei Hu, Guodong Yang, Lijun Yuan, Yunyou Duan and Changyang Xing
    Citation: Journal of Nanobiotechnology 2024 22:178
  24. The current first-line treatment for repairing cartilage defects in clinical practice is the creation of microfractures (MF) to stimulate the release of mesenchymal stem cells (MSCs); however, this method has ...

    Authors: Zhian Chen, Tianhua Zhou, Huan Luo, Zhen Wang, Qiang Wang, Rongmao Shi, Zian Li, Rongqing Pang and Hongbo Tan
    Citation: Journal of Nanobiotechnology 2024 22:177
  25. Cancer stem cells (CSCs) represent both a key driving force and therapeutic target of tumoral carcinogenesis, tumor evolution, progression, and recurrence. CSC-guided tumor diagnosis, treatment, and surveillan...

    Authors: Si Sun, Qiang Yang, Dawei Jiang and Yuan Zhang
    Citation: Journal of Nanobiotechnology 2024 22:176
  26. Nonviral delivery of the CRISPR/Cas9 system provides great benefits for in vivo gene therapy due to the low risk of side effects. However, in vivo gene editing by delivering the Cas9 ribonucleoprotein (RNP) is...

    Authors: San Hae Im, Mincheol Jang, Ji-Ho Park and Hyun Jung Chung
    Citation: Journal of Nanobiotechnology 2024 22:175
  27. Photothermal therapy is favored by cancer researchers due to its advantages such as controllable initiation, direct killing and immune promotion. However, the low enrichment efficiency of photosensitizer in tu...

    Authors: Zhou Lan, Wei-Jia Liu, Wu-Wei Yin, Sheng-Ren Yang, Hao Cui, Ke-Long Zou, Guo-Wang Cheng, Hao Chen, Yan-Hua Han, Lang Rao, Rui Tian, Ling-Ling Li, Yu-Yue Zhao and Guang-Tao Yu
    Citation: Journal of Nanobiotechnology 2024 22:174
  28. Depression is a mood disorder mainly clinically characterized by significant and persistent low spirits. Chronic stress is the leading cause of depression. However, traditional medicine has severe side effects...

    Authors: Ruiyuan Liu, Tianlu Zhang, Chaobo Bai, Jing Chen, Xin Zhang, Guiying Liu, Songjie Shen, Junliang Yuan and Zhiguo Lu
    Citation: Journal of Nanobiotechnology 2024 22:173
  29. Early-onset bone dysplasia is a common manifestation of hypophosphatasia (HPP), an autosomal inherited disease caused by ALPL mutation. ALPL ablation induces prototypical premature bone ageing characteristics,...

    Authors: Jiayi Dong, Wanmin Zhao, Jiangdong Zhao, Ji Chen, Ping Liu, Xueni Zheng, Dehua Li, Yang Xue and Hongzhi Zhou
    Citation: Journal of Nanobiotechnology 2024 22:172
  30. Salivary extracellular vesicles (EVs) have emerged as key tools for non-invasive diagnostics, playing a crucial role in the early detection and monitoring of diseases. These EVs surpass whole saliva in biomark...

    Authors: Li Cui, Jiarong Zheng, Ye Lu, Pei Lin, Yunfan Lin, Yucheng Zheng, Rongwei Xu, Zizhao Mai, Bing Guo and Xinyuan Zhao
    Citation: Journal of Nanobiotechnology 2024 22:171
  31. Neurodegenerative diseases (NDDs) such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis epitomize a class of insidious and relentless neurological conditions that are difficult to...

    Authors: Xixi Liu, Lu Shen, Meidan Wan, Hui Xie and Zhenxing Wang
    Citation: Journal of Nanobiotechnology 2024 22:170
  32. Angiotensin-converting enzyme 2 (ACE2) and AXL tyrosine kinase receptor are known to be involved in the SARS-CoV-2 entry of the host cell. Therefore, targeting ACE2 and AXL should be an effective strategy to i...

    Authors: Jia-You Fang, Kuo-Yen Huang, Tong-Hong Wang, Zih-Chan Lin, Chin-Chuan Chen, Sui-Yuan Chang, En-Li Chen, Tai-Ling Chao, Shuenn-Chen Yang, Pan-Chyr Yang and Chi-Yuan Chen
    Citation: Journal of Nanobiotechnology 2024 22:169
  33. Oral cancer is the most common malignant tumor of the head and neck, and 90% of cases are oral squamous cell carcinoma (OSCC). Chemotherapy is an important component of comprehensive treatment for OSCC. Howeve...

    Authors: Lin Yang, Hongjiao Li, Aihua Luo, Yao Zhang, Hong Chen, Li Zhu and Deqin Yang
    Citation: Journal of Nanobiotechnology 2024 22:168
  34. Sonodynamic therapy (SDT) has shown promise as a non-invasive cancer treatment due to its local effects and excellent tissue penetration. However, the limited accumulation of sonosensitizers at the tumor site ...

    Authors: Meng Du, Ting Wang, Wangrui Peng, Renjie Feng, MeeiChyn Goh and Zhiyi Chen
    Citation: Journal of Nanobiotechnology 2024 22:167
  35. Treatment for inflammatory bowel disease (IBD) is challenging since current anti-inflammatory and immunosuppressive therapies do not address the underlying causes of the illness, which include increased levels...

    Authors: Fan Yang, Yuting Su, Chi Yan, Tianfeng Chen and Peter Chi Keung Cheung
    Citation: Journal of Nanobiotechnology 2024 22:166
  36. As a common musculoskeletal disorder, frozen shoulder is characterized by thickened joint capsule and limited range of motion, affecting 2–5% of the general population and more than 20% of patients with diabet...

    Authors: Zhen Peng, Beijie Qi, Zhiwen Luo, Yaying Sun, Xingyu Zhang, Jinrong Lin, Jinhui Pang, Peng Zhang, Zhihu Zhao, Xianwen Wang and Jiwu Chen
    Citation: Journal of Nanobiotechnology 2024 22:165
  37. Plasma proteins are considered the most informative source of biomarkers for disease diagnosis and monitoring. Mass spectrometry (MS)-based proteomics has been applied to identify biomarkers in plasma, but the...

    Authors: Nan Li, Jingnan Huang, Shangwen He, Qiaocong Zheng, Feng Ye, Zhengxing Qin, Dong Wang, Ting Xiao, Mengyuan Mao, Zhenhua Zhou, Tingxi Tang, Longshan Zhang, Xiaoqing Wang, Yingqiao Wang, Ying Lyu, Laiyu Liu…
    Citation: Journal of Nanobiotechnology 2024 22:164
  38. Photothermal immunotherapy is regarded as the ideal cancer therapeutic modality to against malignant solid tumors; however, its therapeutic benefits are often modest and require improvement. In this study, a t...

    Authors: Pengfei Chen, Chi Zhang, Liuliang He, Mingfei Li, Jie Rong, Pengfei Sun, Yingying Chen and Daifeng Li
    Citation: Journal of Nanobiotechnology 2024 22:163
  39. To overcome the problems of commercial magnetic resonance imaging (MRI) contrast agents (CAs) (i.e., small molecule Gd chelates), we have proposed a new concept of Gd macrochelates based on the coordination of Gd

    Authors: Meng Shi, Wei Xiong, Jie Feng, Lihe Wu, Jing Yang, Yudie Lu, Xuanyi Lu, Qingdeng Fan, Hemin Nie, Yunlu Dai, Chenggong Yan, Ye Tian and Zheyu Shen
    Citation: Journal of Nanobiotechnology 2024 22:162
  40. Antibiotic resistance has garnered significant attention due to the scarcity of new antibiotics in development. Protoporphyrin IX (PpIX)-mediated photodynamic therapy shows promise as a novel antibacterial str...

    Authors: Ying Piao, Sebastian Himbert, Zifan Li, Jun Liu, Zhihao Zhao, Huahai Yu, Shuangshuang Liu, Shiqun Shao, Michael Fefer, Maikel C. Rheinstädter and Youqing Shen
    Citation: Journal of Nanobiotechnology 2024 22:161
  41. Dry eye disease (DED) is associated with ocular hyperosmolarity and inflammation. The marketed topical eye drops for DED treatment often lack bioavailability and precorneal residence time. In this study, we in...

    Authors: Hoang Linh Bui, Yun-Han Su, Chia-Jung Yang, Chun-Jen Huang and Jui-Yang Lai
    Citation: Journal of Nanobiotechnology 2024 22:160
  42. Brain metastasis (BM) is one of the leading causes of cancer-related deaths in patients with advanced non-small cell lung cancer (NSCLC). However, limited treatments are available due to the presence of the bl...

    Authors: Jun Jiang, Yuan Lu, Jie Chu, Xiao Zhang, Chao Xu, Shaojie Liu, Zhuo Wan, Jiawei Wang, Lu Zhang, Kui Liu, Zhenhua Liu, Angang Yang, Xinling Ren and Rui Zhang
    Citation: Journal of Nanobiotechnology 2024 22:159
  43. Osteoarthritis (OA) is a common degenerative joint disease that can cause severe pain, motor dysfunction, and even disability. A growing body of research indicates that gut microbiota and their associated meta...

    Authors: Zihan Deng, Chuan Yang, Tingwen Xiang, Ce Dou, Dong Sun, Qijie Dai, Zhiguo Ling, Jianzhong Xu, Fei Luo and Yueqi Chen
    Citation: Journal of Nanobiotechnology 2024 22:157
  44. Immunotherapy has revolutionized the treatment of cancer. However, its efficacy remains to be optimized. There are at least two major challenges in effectively eradicating cancer cells by immunotherapy. Firstl...

    Authors: Suke Deng, Jiacheng Wang, Yan Hu, Yajie Sun, Xiao Yang, Bin Zhang, Yue Deng, Wenwen Wei, Zhanjie Zhang, Lu Wen, You Qin, Fang Huang, Yuhan Sheng, Chao Wan and Kunyu Yang
    Citation: Journal of Nanobiotechnology 2024 22:156
  45. The combination of immune checkpoint inhibitors and immunogenic cell death (ICD) inducers has become a promising strategy for the treatment of various cancers. However, its efficacy remains unmet because of th...

    Authors: Wenqi Shen, Yecheng Li, Ziyi Yang, Wenjing Li, Yi Cao, Yilin Liu, Zheng Wang, Renjun Pei and Chungen Xing
    Citation: Journal of Nanobiotechnology 2024 22:154
  46. Osteoporosis is characterized by an imbalance in bone homeostasis, resulting in the excessive dissolution of bone minerals due to the acidified microenvironment mediated by overactive osteoclasts. Oroxylin A (...

    Authors: Biao Yu, Qianmin Gao, Shihao Sheng, Fengjin Zhou, Zhen Geng, Yan Wei, Hao Zhang, Yan Hu, Sicheng Wang, Jianping Huang, Mengmeng Li and Jiacan Su
    Citation: Journal of Nanobiotechnology 2024 22:153
  47. Infected wound healing remains a challenging task in clinical practice due to several factors: (I) drug-resistant infections caused by various pathogens, (II) persistent inflammation that hinders tissue regene...

    Authors: Zichao Jiang, Jingyi Li, Jiahao Wang, Yixiao Pan, Shuailong Liang, Yihe Hu and Long Wang
    Citation: Journal of Nanobiotechnology 2024 22:152
  48. Dental pulp regeneration is a promising strategy for addressing tooth disorders. Incorporating this strategy involves the fundamental challenge of establishing functional vascular networks using dental pulp st...

    Authors: Xiaoling Wei, Huaxing Xu, Mengqi Zhou, Qiangqiang Zhou, Mingqiang Li and Yuehua Liu
    Citation: Journal of Nanobiotechnology 2024 22:150

Annual Journal Metrics

  • 2022 Citation Impact
    10.2 - 2-year Impact Factor
    11.5 - 5-year Impact Factor
    1.249 - SNIP (Source Normalized Impact per Paper)
    1.421 - SJR (SCImago Journal Rank)

    2023 Speed
    8 days submission to first editorial decision for all manuscripts (Median)
    85 days submission to accept (Median)

    2023 Usage 
    2,763,562 downloads
    1,483 Altmetric mentions