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  1. Research

    Block copolymer conjugated Au-coated Fe3O4 nanoparticles as vectors for enhancing colloidal stability and cellular uptake

    Polymer surface-modified inorganic nanoparticles (NPs) provide a multifunctional platform for assisting gene delivery. Rational structure design for enhancing colloidal stability and cellular uptake is an impo...

    Junbo Li, Sheng Zou, Jiayu Gao, Ju Liang, Huiyun Zhou, Lijuan Liang and Wenlan Wu

    Journal of Nanobiotechnology 2017 15:56

    Published on: 25 July 2017

  2. Research

    Enzyme adsorption-induced activity changes: a quantitative study on TiO2 model agglomerates

    Activity retention upon enzyme adsorption on inorganic nanostructures depends on different system parameters such as structure and composition of the support, composition of the medium as well as enzyme loadin...

    Augusto Márquez, Krisztina Kocsis, Gregor Zickler, Gilles R. Bourret, Andrea Feinle, Nicola Hüsing, Martin Himly, Albert Duschl, Thomas Berger and Oliver Diwald

    Journal of Nanobiotechnology 2017 15:55

    Published on: 21 July 2017

  3. Research

    A versatile papaya mosaic virus (PapMV) vaccine platform based on sortase-mediated antigen coupling

    Flexuous rod-shaped nanoparticles made of the coat protein (CP) of papaya mosaic virus (PapMV) have been shown to trigger innate immunity through engagement of toll-like receptor 7 (TLR7). PapMV nanoparticles ...

    Ariane Thérien, Mikaël Bédard, Damien Carignan, Gervais Rioux, Louis Gauthier-Landry, Marie-Ève Laliberté-Gagné, Marilène Bolduc, Pierre Savard and Denis Leclerc

    Journal of Nanobiotechnology 2017 15:54

    Published on: 18 July 2017

  4. Research

    Systematic evaluation of oligodeoxynucleotide binding and hybridization to modified multi-walled carbon nanotubes

    In addition to conventional chemotherapeutics, nucleic acid-based therapeutics like antisense oligodeoxynucleotides (AS-ODN) represent a novel approach for the treatment of bladder cancer (BCa). An efficient d...

    Anika Kaufmann, Silke Hampel, Christiane Rieger, David Kunhardt, Darja Schendel, Susanne Füssel, Bernd Schwenzer and Kati Erdmann

    Journal of Nanobiotechnology 2017 15:53

    Published on: 17 July 2017

  5. Letter to the Editor

    Antireflective nanocoatings for UV-sensation: the case of predatory owlfly insects

    Moth-eye nanostructures, discovered to coat corneae of certain nocturnal insects, have inspired numerous technological applications to reduce light reflectance from solar cells, light-emitting diodes, and opti...

    Mikhail Kryuchkov, Jannis Lehmann, Jakob Schaab, Manfred Fiebig and Vladimir L. Katanaev

    Journal of Nanobiotechnology 2017 15:52

    Published on: 14 July 2017

  6. Research

    Interaction of γ-Fe2O3 nanoparticles with Citrus maxima leaves and the corresponding physiological effects via foliar application

    Nutrient-containing nanomaterials have been developed as fertilizers to foster plant growth and agricultural yield through root applications. However, if applied through leaves, how these nanomaterials, e.g. γ-Fe

    Jing Hu, Huiyuan Guo, Junli Li, Yunqiang Wang, Lian Xiao and Baoshan Xing

    Journal of Nanobiotechnology 2017 15:51

    Published on: 11 July 2017

  7. Research

    Cell-based cytotoxicity assays for engineered nanomaterials safety screening: exposure of adipose derived stromal cells to titanium dioxide nanoparticles

    Increasing production of nanomaterials requires fast and proper assessment of its potential toxicity. Therefore, there is a need to develop new assays that can be performed in vitro, be cost effective, and all...

    Yan Xu, M. Hadjiargyrou, Miriam Rafailovich and Tatsiana Mironava

    Journal of Nanobiotechnology 2017 15:50

    Published on: 11 July 2017

  8. Research

    Effects of silica nanoparticle exposure on mitochondrial function during neuronal differentiation

    Nanomedicine offers a promising tool for therapies of brain diseases, but potential effects on neuronal health and neuronal differentiation need to be investigated to assess potential risks. The aim of this st...

    Angélique D. Ducray, Andrea Felser, Jana Zielinski, Aniela Bittner, Julia V. Bürgi, Jean-Marc Nuoffer, Martin Frenz and Meike Mevissen

    Journal of Nanobiotechnology 2017 15:49

    Published on: 4 July 2017

  9. Research

    The agglomeration state of nanoparticles can influence the mechanism of their cellular internalisation

    Significant progress of nanotechnology, including in particular biomedical and pharmaceutical applications, has resulted in a high number of studies describing the biological effects of nanomaterials. Moreover...

    Blanka Halamoda-Kenzaoui, Mara Ceridono, Patricia Urbán, Alessia Bogni, Jessica Ponti, Sabrina Gioria and Agnieszka Kinsner-Ovaskainen

    Journal of Nanobiotechnology 2017 15:48

    Published on: 26 June 2017

  10. Research

    Uptake of label-free graphene oxide by Caco-2 cells is dependent on the cell differentiation status

    Understanding the interaction of graphene-related materials (GRM) with human cells is a key to the assessment of their potential risks for human health. There is a knowledge gap regarding the potential uptake ...

    Melanie Kucki, Liliane Diener, Nils Bohmer, Cordula Hirsch, Harald F. Krug, Vincenzo Palermo and Peter Wick

    Journal of Nanobiotechnology 2017 15:46

    Published on: 21 June 2017

  11. Research

    The role of intracellular trafficking of CdSe/ZnS QDs on their consequent toxicity profile

    Nanoparticle interactions with cellular membranes and the kinetics of their transport and localization are important determinants of their functionality and their biological consequences. Understanding these p...

    Bella B. Manshian, Thomas F. Martens, Karsten Kantner, Kevin Braeckmans, Stefaan C. De Smedt, Jo Demeester, Gareth J. S. Jenkins, Wolfgang J. Parak, Beatriz Pelaz, Shareen H. Doak, Uwe Himmelreich and Stefaan J. Soenen

    Journal of Nanobiotechnology 2017 15:45

    Published on: 15 June 2017

  12. Research

    Comparative efficacy analysis of anti-microbial peptides, LL-37 and indolicidin upon conjugation with CNT, in human monocytes

    Antimicrobial peptides (AMPs) have the potential to serve as an alternative to antibiotic. AMPs usually exert bactericidal activity via direct killing of microbial pathogens. Reports have proposed that by harn...

    Biswaranjan Pradhan, Dipanjan Guha, Krushna Chandra Murmu, Abhinav Sur, Pratikshya Ray, Debashmita Das and Palok Aich

    Journal of Nanobiotechnology 2017 15:44

    Published on: 12 June 2017

  13. Research

    Nasal delivery of nanoliposome-encapsulated ferric ammonium citrate can increase the iron content of rat brain

    Iron deficiency in children can have significant neurological consequences, and iron supplementation is an effective treatment of choice. However, traditional routes of iron supplementation do not allow effici...

    Xueling Guo, Hong Zheng, Yuetong Guo, Yan Wang, Gregory J. Anderson, Yunzhe Ci, Peng Yu, Lina Geng and Yan-Zhong Chang

    Journal of Nanobiotechnology 2017 15:42

    Published on: 2 June 2017

  14. Research

    Synthesis, characterization, and biological verification of anti-HER2 indocyanine green–doxorubicin-loaded polyethyleneimine-coated perfluorocarbon double nanoemulsions for targeted photochemotherapy of breast cancer cells

    Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females worldwide. Among various types of breast cancer, the human epidermal growth factor receptor 2 (HER2)-ov...

    Yu-Hsiang Lee and Yun-Ting Ma

    Journal of Nanobiotechnology 2017 15:41

    Published on: 18 May 2017

  15. Research

    Label-free biosensing of Salmonella enterica serovars at single-cell level

    The emerging nanotechnologies have greatly facilitated the development of label-free biosensors. The atomic force microscopy (AFM) has been used to study the molecular mechanism of the reactions for protein an...

    Bin Wang, Bosoon Park, Bingqian Xu and Yongkuk Kwon

    Journal of Nanobiotechnology 2017 15:40

    Published on: 17 May 2017

  16. Short Communication

    Tracking single baculovirus retrograde transportation in host cell via quantum dot-labeling of virus internal component

    Quantum dot (QD)-based single virus tracking has become a powerful tool for dissecting virus infection mechanism. However, only virus behaviors at the early stage of retrograde trafficking have been dynamicall...

    Li Wen, Zhen-Hua Zheng, An-An Liu, Cheng Lv, Li-Juan Zhang, Jian Ao, Zhi-Ling Zhang, Han-Zhong Wang, Yi Lin and Dai-Wen Pang

    Journal of Nanobiotechnology 2017 15:37

    Published on: 6 May 2017

  17. Research

    A mechanistic investigation exploring the differential transfection efficiencies between the easy-to-transfect SK-BR3 and difficult-to-transfect CT26 cell lines

    Gold–polyamidoamine (AuPAMAM) has previously been shown to successfully transfect cells with high efficiency. However, we have observed that certain cell types are more amenable to Au–PAMAM transfection than o...

    Elizabeth Figueroa, Pallavi Bugga, Vishwaratn Asthana, Allen L. Chen, J. Stephen Yan, Emily Reiser Evans and Rebekah A. Drezek

    Journal of Nanobiotechnology 2017 15:36

    Published on: 2 May 2017

  18. Research

    Highly sensitive and accurate detection of C-reactive protein by CdSe/ZnS quantum dot-based fluorescence-linked immunosorbent assay

    The conventional and widely used enzyme-linked immunosorbent assays (ELISA), due to specificity and high-sensitivity, were suitable in vitro diagnosis. But enzymes are vulnerable to the external conditions, an...

    Yanbing Lv, Ruili Wu, Kunrui Feng, Jinjie Li, Qing Mao, Hang Yuan, Huaibin Shen, Xiangdong Chai and Lin Song Li

    Journal of Nanobiotechnology 2017 15:35

    Published on: 2 May 2017

  19. Research

    A retro-inverso cell-penetrating peptide for siRNA delivery

    Small interfering RNAs (siRNAs) are powerful tools to control gene expression. However, due to their poor cellular permeability and stability, their therapeutic development requires a specific delivery system....

    Anaïs Vaissière, Gudrun Aldrian, Karidia Konate, Mattias F. Lindberg, Carole Jourdan, Anthony Telmar, Quentin Seisel, Frédéric Fernandez, Véronique Viguier, Coralie Genevois, Franck Couillaud, Prisca Boisguerin and Sébastien Deshayes

    Journal of Nanobiotechnology 2017 15:34

    Published on: 28 April 2017

  20. Review

    Nanoparticles based on essential metals and their phytotoxicity

    Nanomaterials in agriculture are becoming popular due to the impressive advantages of these particles. However, their bioavailability and toxicity are key features for their massive employment. Herein, we comp...

    Branislav Ruttkay-Nedecky, Olga Krystofova, Lukas Nejdl and Vojtech Adam

    Journal of Nanobiotechnology 2017 15:33

    Published on: 26 April 2017

  21. Research

    Aggregation/dispersion transitions of T4 phage triggered by environmental ion availability

    Bacteriophage survives in at least two extremes of ionic environments: bacterial host (high ionic-cytosol) and that of soil (low ionic-environmental water). The impact of ionic composition in the micro- and macro...

    Bożena Szermer-Olearnik, Marek Drab, Mateusz Mąkosa, Maria Zembala, Jakub Barbasz, Krystyna Dąbrowska and Janusz Boratyński

    Journal of Nanobiotechnology 2017 15:32

    Published on: 24 April 2017

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