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  1. The deployment of imaging examinations has evolved into a robust approach for the diagnosis of lymph node metastasis (LNM). The advancement of technology, coupled with the introduction of innovative imaging dr...

    Authors: Ze-Min Cai, Zi-Zhan Li, Nian-Nian Zhong, Lei-Ming Cao, Yao Xiao, Jia-Qi Li, Fang-Yi Huo, Bing Liu, Chun Xu, Yi Zhao, Lang Rao and Lin-Lin Bu
    Citation: Journal of Nanobiotechnology 2024 22:135
  2. Corneal neovascularization (CoNV) threatens vision by disrupting corneal avascularity, however, current treatments, including pharmacotherapy and surgery, are hindered by limitations in efficacy and adverse ef...

    Authors: Zitong Li, Wenpeng Huang, Ming Zhang, Yan Huo, Feifei Li, Lele Song, Sitong Wu, Qi Yang, Xiaoming Li, Jianjun Zhang, Liu Yang, Jianchen Hao and Lei Kang
    Citation: Journal of Nanobiotechnology 2024 22:134
  3. Bone defects in the maxillofacial region restrict the integrity of dental function, posing challenges in clinical treatment. Bone tissue engineering (BTE) with stem cell implants is an effective method. Nanobi...

    Authors: Na An, Xiaoyuan Yan, Qiujing Qiu, Zeying Zhang, Xiyue Zhang, Bowen Zheng, Zhenjin Zhao, Jiajie Guo and Yi Liu
    Citation: Journal of Nanobiotechnology 2024 22:133
  4. Cardiovascular diseases (CVDs) have the highest mortality worldwide. Human pluripotent stem cells (hPSCs) and their cardiomyocyte derivatives (hPSC-CMs) offer a valuable resource for disease modeling, pharmaco...

    Authors: Chengwen Hang, Mohamed S. Moawad, Zheyi Lin, Huixin Guo, Hui Xiong, Mingshuai Zhang, Renhong Lu, Junyang Liu, Dan Shi, Duanyang Xie, Yi Liu, Dandan Liang, Yi-Han Chen and Jian Yang
    Citation: Journal of Nanobiotechnology 2024 22:132
  5. Effective intracellular DNA transfection is imperative for cell-based therapy and gene therapy. Conventional gene transfection methods, including biochemical carriers, physical electroporation and microinjecti...

    Authors: Juan Jiang, Jing Liu, Xinmin Liu, Xingyuan Xu, Zhengjie Liu, Shuang Huang, Xinshuo Huang, Chuanjie Yao, Xiafeng Wang, Yixin Chen, Hui-jiuan Chen, Ji Wang and Xi Xie
    Citation: Journal of Nanobiotechnology 2024 22:131
  6. Traditional eye drops are administered via topical instillation. However, frequent dosing is needed due to their relatively rapid precorneal removal and low ocular bioavailability. To address these issues, ste...

    Authors: Bo Tang, Qiuxiang Wang, Guowei Zhang, Aiwen Zhang, Lu Zhu, Rongrong Zhao, Hongwei Gu, Jie Meng, Junfang Zhang and Guihua Fang
    Citation: Journal of Nanobiotechnology 2024 22:130
  7. The development of nanomaterials for delivering natural compounds has emerged as a promising approach for atherosclerosis therapy. However, premature drug release remains a challenge. Here, we present a ROS-re...

    Authors: Zhenxian Li, Haimei Zhu, Hao Liu, Dayue Liu, Jianhe Liu, Yi Zhang, Zhang Qin, Yijia Xu, Yuan Peng, Lihua Ruan, Jintao Li, Yao He, Bin Liu and Yun Long
    Citation: Journal of Nanobiotechnology 2024 22:129
  8. Accumulating evidence supports the notion that microglia play versatile roles in different chronic pain conditions. However, therapeutic strategies of chronic pain by targeting microglia remain largely overloo...

    Authors: Yitian Lu, Shuai Liu, Peng Wang, Xiangna Guo, Zaisheng Qin, Honghao Hou and Tao Tao
    Citation: Journal of Nanobiotechnology 2024 22:128
  9. The rapid proliferation of tumors is highly dependent on the nutrition supply of blood vessels. Cutting off the nutrient supply to tumors is an effective strategy for cancer treatment, known as starvation ther...

    Authors: Xueyan Liu, Tingting Hu, Yijiang Jia, Shuqing Yang, Yu Yang, Zhuolin Cui, Tao Wang, Ruizheng Liang, Chaoliang Tan and Yuji Wang
    Citation: Journal of Nanobiotechnology 2024 22:127
  10. The successful reprogramming of impaired wound healing presents ongoing challenges due to the impaired tissue microenvironment caused by severe bacterial infection, excessive oxidative stress, as well as the i...

    Authors: Yuan Peng, Yicheng Guo, Xin Ge, Yali Gong, Yuhan Wang, Zelin Ou, Gaoxing Luo, Rixing Zhan and Yixin Zhang
    Citation: Journal of Nanobiotechnology 2024 22:126
  11. After intracerebral hemorrhage (ICH) occurs, the overproduction of reactive oxygen species (ROS) and iron ion overload are the leading causes of secondary damage. Removing excess iron ions and ROS in the menin...

    Authors: Xiaolong Tang, Xinyu Yang, Yamei Yu, Miaojing Wu, Yuanyuan Li, Zhe Zhang, Guangyu Jia, Qi Wang, Wei Tu, Ye Wang, Xingen Zhu and Shiyong Li
    Citation: Journal of Nanobiotechnology 2024 22:125
  12. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have garnered extensive attention as natural product-based nanomedicines and potential drug delivery vehicles. However, the specific mechanism for...

    Authors: Zhixiao Liu, Yingying Liu, Yu Li, Sha Xu, Yang Wang, Yuruchen Zhu, Chu Jiang, Kaizhe Wang, Yinan Zhang and Yue Wang
    Citation: Journal of Nanobiotechnology 2024 22:124
  13. Photodynamic therapy (PDT) efficacy of bismuth sulfide (Bi2S3) semiconductor has been severely restricted by its electron–hole pairs (e−−h+) separation inefficiency and oxygen (O2) deficiency in tumors, which gre...

    Authors: Hanwen Jiang, Jingxian Sun, Fucong Liu, Yuanjiao Zhao, Xin Chen, Changsong Dai and Zhaohui Wen
    Citation: Journal of Nanobiotechnology 2024 22:123
  14. Endocrine therapy is standard for hormone receptor–positive (HR+) breast cancer treatment. However, current strategies targeting estrogen signaling pay little attention to estradiol metabolism in the liver and is...

    Authors: Yuying Zhao, Hanxu Tan, Juping Zhang, Dandan Zhan, Bowen Yang, Shicui Hong, Bo Pan, Neng Wang, Tongkai Chen, Yafei Shi and Zhiyu Wang
    Citation: Journal of Nanobiotechnology 2024 22:122
  15. Traditional pesticides are poorly water-soluble and suffer from low bioavailability. N-succinyl chitosan (NSCS) is a water-soluble chitosan derivative, has been recently used to encapsulate hydrophobic drugs to i...

    Authors: Qing Zhou, Zhi Xia, Yu Zhang, Zhiling Sun, Wei Zeng, Nian Zhang, Chunmei Yuan, Chenyu Gong, Yuanxiang Zhou and Wei Xue
    Citation: Journal of Nanobiotechnology 2024 22:121
  16. Acute lung injury (ALI) is a fatal respiratory disease caused by overreactive immune reactions (e.g., SARS-CoV-2 infection), with a high mortality rate. Its treatment is often compromised by inefficient drug d...

    Authors: Huan Shen, Li Pan, Keke Ning, Yuefei Fang, Bahtiyor Muhitdinov, Ergang Liu and Yongzhuo Huang
    Citation: Journal of Nanobiotechnology 2024 22:119
  17. The assessment of AgNPs toxicity in vitro and in vivo models are frequently conflicting and inaccurate. Nevertheless, single cell immunological responses in a heterogenous environment have received little atte...

    Authors: Haribalan Perumalsamy, Xiao Xiao, Hyun-Yi Kim and Tae-Hyun Yoon
    Citation: Journal of Nanobiotechnology 2024 22:118
  18. Reactive oxygen species (ROS) has emerged as potent therapeutic agents for biofilm-associated bacterial infections. Chemodynamic therapy (CDT), involving the generation of high-energy ROS, displays great poten...

    Authors: Yulan Zhao, Yang Wu, Quan Xu, Yi Liu, Zhiyong Song and Heyou Han
    Citation: Journal of Nanobiotechnology 2024 22:117
  19. In the inflammatory milieu of diabetic chronic wounds, macrophages undergo substantial metabolic reprogramming and play a pivotal role in orchestrating immune responses. Itaconic acid, primarily synthesized by...

    Authors: Jibing He, Shasha Zhou, Jiaxing Wang, Binbin Sun, Dalong Ni, Jinglei Wu and Xiaochun Peng
    Citation: Journal of Nanobiotechnology 2024 22:116
  20. Photoacoustic (PA) imaging is a diagnostic modality that combines the high contrast resolution of optical imaging with the high tissue penetration of ultrasound. While certain endogenous chromophores can be vi...

    Authors: Rui Zhang, Sven Thoröe-Boveleth, Dmitry N. Chigrin, Fabian Kiessling, Twan Lammers and Roger M. Pallares
    Citation: Journal of Nanobiotechnology 2024 22:115
  21. Rice bran a by-product of the rice milling process is currently underutilized. Recent studies have shown that plant-derived nanoparticles (pdNPs) can be mass-produced at a low cost and exhibit biological and t...

    Authors: Daisuke Sasaki, Hinako Suzuki, Kosuke Kusamori, Shoko Itakura, Hiroaki Todo and Makiya Nishikawa
    Citation: Journal of Nanobiotechnology 2024 22:114
  22. Wounds are one of the most common health issues, and the cost of wound care and healing has continued to increase over the past decade. In recent years, there has been growing interest in developing innovative...

    Authors: Wanqing Zou, Jing Lu, Luyong Zhang and Duanping Sun
    Citation: Journal of Nanobiotechnology 2024 22:113
  23. The challenges posed by delayed atrophic healing and nonunion stand as formidable obstacles in osteoporotic fracture treatment. The processes of type H angiogenesis and osteogenesis emerge as pivotal mechanism...

    Authors: Xiaoqun Li, Shuo Fang, Shaohai Wang, Yang Xie, Yan Xia, Panfeng Wang, Zichen Hao, Shuogui Xu and Yuntong Zhang
    Citation: Journal of Nanobiotechnology 2024 22:112
  24. Brain damage is a common tissue damage caused by trauma or diseases, which can be life-threatening. Stem cell implantation is an emerging strategy treating brain damage. The stem cell is commonly embedded in a...

    Authors: Zhangze Yang, Yuxin You, Xiangyu Liu, Quan Wan, Zongpu Xu, Yajun Shuai, Jie Wang, Tingbiao Guo, Jiaqi Hu, Junhui Lv, Meng Zhang, Mingying Yang, Chuanbin Mao and Shuxu Yang
    Citation: Journal of Nanobiotechnology 2024 22:111
  25. Breast cancer ranks first among malignant tumors, of which triple-negative breast cancer (TNBC) is characterized by its highly invasive behavior and the worst prognosis. Timely diagnosis and precise treatment ...

    Authors: Ruoyao Wang, Long Cheng, Lingyun He, Chier Du, Haiyang Wang, Bohao Peng, Xiaoqing Yu, Weiwei Liu, Wenpei Luo, Haitao Ran and Lu Yang
    Citation: Journal of Nanobiotechnology 2024 22:110
  26. Immunogenic cell death (ICD) is a crucial approach to turn immunosuppressive tumor microenvironment (ITM) into immune-responsive milieu and improve the response rate of immune checkpoint blockade (ICB) therapy...

    Authors: Jinseong Kim, Man Kyu Shim, Yujeong Moon, Jeongrae Kim, Hanhee Cho, Wan Su Yun, Nayeon Shim, Joon-Kyung Seong, Yonghyun Lee, Dong-Kwon Lim and Kwangmeyung Kim
    Citation: Journal of Nanobiotechnology 2024 22:109
  27. Neurotrauma, encompassing traumatic brain injuries (TBI) and spinal cord injuries (SCI) impacts a significant portion of the global population. While spontaneous recovery post-TBI or SCI is possible, recent ad...

    Authors: Xinyu Nie, Tianyang Yuan, Tong Yu, Zhihe Yun, Tao Yu and Qinyi Liu
    Citation: Journal of Nanobiotechnology 2024 22:108
  28. Breast cancer is the most prevalent malignant tumor among women, with hormone receptor-positive cases constituting 70%. Fulvestrant, an antagonist for these receptors, is utilized for advanced metastatic hormo...

    Authors: Li Zhi, Chen Cheng, Luo Jing, Peng Zhi-Ping, Yang Lu, Tian Yan, Wang Zhi-Gang and Yin Guo-Bing
    Citation: Journal of Nanobiotechnology 2024 22:107
  29. Understanding the intricate nanoscale architecture of neuronal myelin during central nervous system development is of utmost importance. However, current visualization methods heavily rely on electron microsco...

    Authors: Junyang Chen, Yifan Yu, Siyou Wang, Yu Shen, Yupeng Tian, Loris Rizzello, Kui Luo, Xiaohe Tian, Tinghua Wang and Liulin Xiong
    Citation: Journal of Nanobiotechnology 2024 22:106
  30. Chemotherapy is an important therapeutic approach for malignant tumors for it triggers apoptosis of cancer cells. However, chemotherapy also induces senescence of stromal cells in the tumor microenvironment to...

    Authors: Liangzhi Gong, Zhengsheng Chen, Kai Feng, Lei Luo, Juntao Zhang, Ji Yuan, Yajing Ren, Yang Wang, Xianyou Zheng and Qing Li
    Citation: Journal of Nanobiotechnology 2024 22:105
  31. Modulating macrophages presents a promising avenue in tumor immunotherapy. However, tumor cells have evolved mechanisms to evade macrophage activation and phagocytosis. Herein, we introduced a bispecific antib...

    Authors: Haoqi Zhang, Yuanke Li, Helong Kang, Jingping Lan, Lin Hou, Zhengbang Chen, Fan Li, Yanqin Liu, Jiliang Zhao, Na Li, Yajuan Wan, Yiping Zhu, Zhen Zhao, Hongkai Zhang, Jie Zhuang and Xinglu Huang
    Citation: Journal of Nanobiotechnology 2024 22:104
  32. Rheumatoid arthritis (RA) is a prevalent inflammatory autoimmune disease characterised by persistent inflammation and joint damage with elevated levels of reactive oxygen species (ROS). Current treatment modal...

    Authors: Tian Xia, Yuting Zhu, Kaiqiang Li, Ke Hao, Yingqian Chai, Hongyi Jiang, Chao Lou, Jiachen Yu, Wei Yang, Jilong Wang, Junjie Deng and Zhen Wang
    Citation: Journal of Nanobiotechnology 2024 22:103
  33. Bone tissue engineering scaffolds may provide a potential strategy for onlay bone grafts for oral implants. For determining the fate of scaffold biomaterials and osteogenesis effects, the host immune response ...

    Authors: Yaowei Xuan, Yibo Guo, Lin Li, Yuzhang, Chenping Zhang, RuiJin, Xuelai Yin and Zhen Zhang
    Citation: Journal of Nanobiotechnology 2024 22:102
  34. Radiotheranostics differs from the vast majority of other cancer therapies in its capacity for simultaneous imaging and therapy, and it is becoming more widely implemented. A balance between diagnostic and tre...

    Authors: Hongzhang Yang, Xinying Zeng, Jia Liu, Jingchao Li, Yun Li, Qinglin Zhang, Linlin Shu, Huanhuan Liu, Xueqi Wang, Yuanyuan Liang, Ji Hu, Lumei Huang, Zhide Guo and Xianzhong Zhang
    Citation: Journal of Nanobiotechnology 2024 22:101
  35. Despite the higher sensitivity of melanoma towards ferroptosis and photodynamic therapy (PDT), the lack of efficient ferroptosis inducers and the poor solubility of photosensitizers restrict their synergistic ...

    Authors: Haiqiu Li, Yichen Dou, Hang Yang, Hanlin Xing, Cheng Zhu, Tao Wang, Zhaopeng Xuan and Mingxi Yang
    Citation: Journal of Nanobiotechnology 2024 22:100
  36. The Influenza A virus (IAV) is a zoonotic pathogen that infects humans and various animal species. Infection with IAV can cause fever, anorexia, and dyspnea and is often accompanied by pneumonia characterized ...

    Authors: Ruijing Su, Xinsen Li, Jin Xiao, Jiawei Xu, Jijing Tian, Tianlong Liu and Yanxin Hu
    Citation: Journal of Nanobiotechnology 2024 22:99
  37. Chemodynamic therapy (CDT) based on intracellular Fenton reaction to produce highly cytotoxic reactive oxygen species (ROS) has played an essential role in tumor therapy. However, this therapy still needs to b...

    Authors: Wenting Chen, Fangfang Hu, Qian Gao, Caiyun Zheng, Que Bai, Jinxi Liu, Na Sun, Wenhui Zhang, Yanni Zhang, Kai Dong and Tingli Lu
    Citation: Journal of Nanobiotechnology 2024 22:98
  38. Immune checkpoint blockers (ICBs) have been applied for cancer therapy and achieved great success in the field of cancer immunotherapy. Nevertheless, the broad application of ICBs is limited by the low respons...

    Authors: Wen Deng, Haojie Shang, Yonghua Tong, Xiao Liu, Qiu Huang, Yu He, Jian Wu, Xiaozhuo Ba, Zhiqiang Chen, Yuan Chen and Kun Tang
    Citation: Journal of Nanobiotechnology 2024 22:97
  39. Nanoplastics (NPs) are now a new class of pollutants widely present in the soil, atmosphere, freshwater and marine environments. Nanoplastics can rapidly penetrate cell membranes and accumulate in human tissue...

    Authors: Kaihao Wang, Yipeng Du, Peixin Li, Chang Guan, Min Zhou, Lanlan Wu, Zengfu Liu and Zheng Huang
    Citation: Journal of Nanobiotechnology 2024 22:96
  40. The prognosis for hepatocellular carcinoma (HCC) remains suboptimal, characterized by high recurrence and metastasis rates. Although metalloimmunotherapy has shown potential in combat...

    Authors: Qianying Du, Ying Luo, Lian Xu, Chier Du, Wenli Zhang, Jie Xu, Yun Liu, Bo Liu, Sijin Chen, Yi Wang, Zhigang Wang, Haitao Ran, Junrui Wang and Dajing Guo
    Citation: Journal of Nanobiotechnology 2024 22:95
  41. Impaired osteo-/angiogenesis, excessive inflammation, and imbalance of the osteoimmune homeostasis are involved in the pathogenesis of the alveolar bone defect caused by periodontitis. Unfortunately, there is ...

    Authors: Shi-Yuan Yang, Yue Hu, Ran Zhao, Yu-Ning Zhou, Yu Zhuang, Yan Zhu, Xiao-Li Ge, Ting-Wei Lu, Kai-Li Lin and Yuan-Jin Xu
    Citation: Journal of Nanobiotechnology 2024 22:94
  42. Glioma is easy to develop resistance to temozolomide (TMZ). TMZ-resistant glioma secretes interleukin-10 (IL-10) and transforming growth factor-β (TGF-β), recruiting regulatory T cell (Treg) and inhibiting the ac...

    Authors: Xue Li, Ying Cheng, Zhifu Yang, Qifeng Ji, Menglei Huan, Weiliang Ye, Miao Liu, Bangle Zhang, Daozhou Liu and Siyuan Zhou
    Citation: Journal of Nanobiotechnology 2024 22:93
  43. Gold nanoparticles (GNPs) have been extensively recognized as an active candidate for a large variety of biomedical applications. However, the clinical conversion of specific types of GNPs has been hindered du...

    Authors: Rui Zhang, Dan Li, Ruibo Zhao, Dandan Luo, Yeting Hu, Shengyan Wang, Xiaolu Zhuo, M. Zubair Iqbal, Han Zhang, Qianqian Han and Xiangdong Kong
    Citation: Journal of Nanobiotechnology 2024 22:92
  44. The primary factors that restrict agricultural productivity and jeopardize human and food safety are heavy metals (HMs), including arsenic, cadmium, lead, and aluminum, which adversely impact crop yields and q...

    Authors: Abazar Ghorbani, Abolghassem Emamverdian, Necla Pehlivan, Meisam Zargar, Seyed Mehdi Razavi and Moxian Chen
    Citation: Journal of Nanobiotechnology 2024 22:91
  45. Immune checkpoint inhibitor (ICI)-derived evolution offers a versatile means of developing novel immunotherapies that targets programmed death-ligand 1 (PD-L1)/programmed death-1 (PD-1) axis. However, one majo...

    Authors: Xiaowei Han, Guozheng Zhang, Xiaozhen Wu, Shufeng Xu, Jiahuan Liu, Kaikai Wang, Tianqing Liu and Pengkai Wu
    Citation: Journal of Nanobiotechnology 2024 22:90
  46. Despite advances in surgery and chemotherapy, the survival of patients with osteosarcoma (OS) has not been fundamentally improved over the last two decades. Microvesicles (MVs) have a high cargo-loading capaci...

    Authors: Zhenggang Wang, Zhiyi He, Junlai Wan, Anmin Chen, Peng Cheng and Wentao Zhu
    Citation: Journal of Nanobiotechnology 2024 22:89
  47. Functional metal doping endows fluorescent carbon dots with richer physical and chemical properties, greatly expanding their potential in the biomedical field. Nonetheless, fabricating carbon dots with integra...

    Authors: Yupeng Shi, Yaning Xia, Mengyang Zhou, Yifei Wang, Jianfeng Bao, Yong Zhang and Jingliang Cheng
    Citation: Journal of Nanobiotechnology 2024 22:88
  48. Impaired collateral formation is a major factor contributing to poor prognosis in type 2 diabetes mellitus (T2DM) patients with atherosclerotic cardiovascular disease. However, the current pharmacological trea...

    Authors: Yixuan Wang, Feifei Li, Linshuang Mao, Yu Liu, Shuai Chen, Jingmeng Liu, Ke Huang, Qiujing Chen, Jianrong Wu, Lin Lu, Yuanyi Zheng, Weifeng Shen, Tao Ying, Yang Dai and Ying Shen
    Citation: Journal of Nanobiotechnology 2024 22:85

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