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  1. Ischemic stroke is a complex, high-mortality disease with multifactorial etiology and pathogenesis. Currently, drug therapy is mainly used treat ischemic stroke in clinic, but there are still some limitations,...

    Authors: Lin Zhu, Weijie Zhong, Xuchen Meng, Xiaosheng Yang, Wenchuan Zhang, Yayuan Tian and Yi Li
    Citation: Journal of Nanobiotechnology 2024 22:424
  2. Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by synovitis and cartilage destruction. The active compound, icariin (ICA), derived from the herb Epimedium, exhibits potent anti-inflammatory p...

    Authors: Qiqi Yan, Haixia Liu, Shiyue Sun, Yongsheng Yang, DanPing Fan, Yuqin Yang, Yukun Zhao, Zhiqian Song, Yanjing Chen, Ruyuan Zhu and Zhiguo Zhang
    Citation: Journal of Nanobiotechnology 2024 22:423
  3. Vascularization plays a significant role in promoting the expedited process of bone regeneration while also enhancing the stability and viability of artificial bone implants. Although titanium alloy scaffolds ...

    Authors: Jie Wu, Leyi Liu, Weidong Du, Yunyang Lu, Runze Li, Chao Wang, Duoling Xu, Weili Ku, Shujun Li, Wentao Hou, Dongsheng Yu and Wei Zhao
    Citation: Journal of Nanobiotechnology 2024 22:422
  4. Prostate cancer (PCa) is the most prevalent cancer among males, emphasizing the critical need for precise diagnosis and treatment to enhance patient prognosis. Recent studies have extensively utilized urine ex...

    Authors: Songlu Liu, Wenting Shang, Jian Song, Qiubai Li and Liang Wang
    Citation: Journal of Nanobiotechnology 2024 22:421
  5. Triple negative breast cancer (TNBC) has the characteristics of low immune cell infiltration, high expression of tumor programmed death ligand 1 (PD-L1), and abundant cancer stem cells. Systemic toxicity of tr...

    Authors: Yan Zhao, Yuansong Bai, Mei Li, Xin Nie, Hao Meng, Shimizu Shosei, Linlin Liu, Qingbiao Yang, Meili Shen and Yapeng Li
    Citation: Journal of Nanobiotechnology 2024 22:420
  6. Iron oxide nanoparticles (IONPs) have been cleared by the Food and Drug Administration (FDA) for various clinical applications, such as tumor-targeted imaging, hyperthermia therapy, drug delivery, and live-cel...

    Authors: Minseok Suh, Ji Yong Park, Guen Bae Ko, Ji Yoon Kim, Do Won Hwang, Louis Rees, Gillian E Conway, Shareen H Doak, Hyelim Kang, Nohyun Lee, Taeghwan Hyeon, Yun-Sang Lee and Dong Soo Lee
    Citation: Journal of Nanobiotechnology 2024 22:419
  7. Sirolimus (SR) is a macrolide with antifungal and antitumor immunosuppressant properties, classified as a selective inhibitor of mammalian target of rapamycin (mTOR). In this study, an ionic in situ gel of SR ...

    Authors: Ye Liu, Xu Chen, Xinghao Chen, Jie Chen, Han Zhang, Haonan Xu, Lu Jin, Qiao Wang and Zhan Tang
    Citation: Journal of Nanobiotechnology 2024 22:417
  8. Reactive oxygen species (ROS)-associated anticancer approaches usually suffer from two limitations, i.e., insufficient ROS level and short ROS half-life. Nevertheless, no report has synchronously addressed bot...

    Authors: Yujia Fang, Jianjun Yang, Xiayi Liang, Jing Wu, Mengqing Xie, Kun Zhang and Chunxia Su
    Citation: Journal of Nanobiotechnology 2024 22:416
  9. Staphylococcus aureus (SA) poses a serious risk to human and animal health, necessitating a low-cost and high-performance analytical platform for point-of-care diagnostics. Cellulose paper-based field-effect tran...

    Authors: Hui Wang, Ruipeng Chen, Yue He, Xiaoyan Zhu, Zhixue Yu, Zemeng Feng, Dongxia Pan, Liang Yang, Xiangfang Tang and Benhai Xiong
    Citation: Journal of Nanobiotechnology 2024 22:414
  10. Peripheral arterial diseases (PAD) have been reported to be the leading cause for limb amputations, and the current therapeutic strategies including antiplatelet medication or intervene surgery are reported to...

    Authors: Yue Wang, Jun Liu, Changgui Tong, Lei Li, Hongyang Cui, Liuwei Zhang, Ming Zhang, Shijia Zhang, Kehui Zhou, Xiabin Lan, Qixian Chen and Yan Zhao
    Citation: Journal of Nanobiotechnology 2024 22:413
  11. The senescence of nucleus pulposus (NP) cells (NPCs), which is induced by the anomalous accumulation of reactive oxygen species (ROS), is a major cause of intervertebral disc degeneration (IVDD). In this resea...

    Authors: Wenzhen Bu, Yu Shi, Xueping Huang, Shang Wu, Letao Jiang, Chun Pan, Dandan Li, Zhuobin Xu, Huihui Wang, Hao Chen and Jianwei Du
    Citation: Journal of Nanobiotechnology 2024 22:412
  12. The fracture healing outcome is largely dependent on the quantities as well as osteogenic differentiation capacities of mesenchymal stem cells (MSCs) at the lesion site. Herein, macrophage membrane (MM)-revers...

    Authors: Cheng Wu, Jing Yan, Chenglong Ge, Lucheng Xie, Yunjie He, Ziyin Zhao, Yekun Deng, Qirong Dong and Lichen Yin
    Citation: Journal of Nanobiotechnology 2024 22:411
  13. Recapitulating the natural extracellular physical microenvironment has emerged as a promising method for tissue regeneration, as multiple physical interventions, including ultrasound, thermal and electrical th...

    Authors: Haoqi Lei, Jiwei Sun, Zhiyin Dai, Keqi Wo, Junyuan Zhang, Yifan Wang, Baoying Zhao, Wenjie Fan, Jinyu Wang, Yunsong Shi, Cheng Yang, Bin Su, Zhiqiang Luo, Junjie Wu, Lili Chen and Yingying Chu
    Citation: Journal of Nanobiotechnology 2024 22:410
  14. This study aimed to investigate the critical role of MDSCs in CRC immune suppression, focusing on the CSF1R and JAK/STAT3 signaling axis. Additionally, it assessed the therapeutic efficacy of LNCs@CSF1R siRNA ...

    Authors: Xin Tong, Shifeng Qiao, Zhe Dong, Xiaohui Zhao, Xiaxia Du and Wei Niu
    Citation: Journal of Nanobiotechnology 2024 22:409
  15. Ovarian cancer (OC) has the highest fatality rate among all gynecological malignancies, necessitating the exploration of novel, efficient, and low-toxicity therapeutic strategies. Ferroptosis is a type of prog...

    Authors: Shuangshuang Cheng, Ting Zhou, Yue Luo, Jun Zhang, Kejun Dong, Qi Zhang, Wan Shu, Tangansu Zhang, Qian Zhang, Rui Shi, Yuwei Yao and Hongbo Wang
    Citation: Journal of Nanobiotechnology 2024 22:408
  16. Segmental bone defects, arising from factors such as trauma, tumor resection, and congenital malformations, present significant clinical challenges that often necessitate complex reconstruction strategies. Hyd...

    Authors: Xi He, Yanling Liu, Zhongyu Dai, Yu Chen, Wenbin Liu, Honglian Dai and Yihe Hu
    Citation: Journal of Nanobiotechnology 2024 22:407
  17. Inclusion bodies (IBs) are well-known subcellular structures in bacteria where protein aggregates are collected. Various methods have probed their structure, but single-cell spectroscopy remains challenging. A...

    Authors: Wouter Duverger, Grigoria Tsaka, Ladan Khodaparast, Laleh Khodaparast, Nikolaos Louros, Frederic Rousseau and Joost Schymkowitz
    Citation: Journal of Nanobiotechnology 2024 22:406
  18. Following spinal cord injury (SCI), the inflammatory storm initiated by microglia/macrophages poses a significant impediment to the recovery process. Exosomes play a crucial role in the transport of miRNAs, fa...

    Authors: Jie Liu, Guang Kong, Chenlin Lu, Juan Wang, Wenbo Li, Zhengming Lv, Jian Tong, Yuan Liu, Wu Xiong, Haijun Li and Jin Fan
    Citation: Journal of Nanobiotechnology 2024 22:403
  19. Tendon injuries are common orthopedic ailments with a challenging healing trajectory, especially in cases like the Achilles tendon afflictions. The healing trajectory of tendon injuries is often suboptimal, le...

    Authors: Yichen Dou, Hong Zhai, Haiqiu Li, Hanlin Xing, Cheng Zhu and Zhaopeng Xuan
    Citation: Journal of Nanobiotechnology 2024 22:401
  20. Considerable attention has been directed towards exploring the potential efficacy of miR-155 in the realm of cancer immunotherapy. Elevated levels of miR-155 in dendritic cells (DCs) have been shown to enhance...

    Authors: Kangkang Li, Juan Wang, Yi Xie, Ziyao Lu, Wen Sun, Kaixuan Wang, Jinxin Liang and Xuehong Chen
    Citation: Journal of Nanobiotechnology 2024 22:400
  21. Spinal cord injury (SCI) represents a profound central nervous system affliction, resulting in irreversibly compromised daily activities and disabilities. SCI involves excessive inflammatory responses, which a...

    Authors: Genjiang Zheng, Wei Yu, Zeng Xu, Chen Yang, Yunhao Wang, Zhihao Yue, Qiangqiang Xiao, Wenyu Zhang, Xiaodong Wu, Fazhi Zang, Jianxi Wang, Lei Wang, Wei-En Yuan, Bo Hu and Huajiang Chen
    Citation: Journal of Nanobiotechnology 2024 22:399
  22. Diabetic wounds are characterized by incomplete healing and delayed healing, resulting in a considerable global health care burden. Exosomes are lipid bilayer structures secreted by nearly all cells and expres...

    Authors: Yichuan Li, Zhanyong Zhu, Sicheng Li, Xiaohang Xie, Lei Qin, Qi Zhang, Yan Yang, Ting Wang and Yong Zhang
    Citation: Journal of Nanobiotechnology 2024 22:398
  23. Failed skin wound healing, through delayed wound healing or wound dehiscence, is a global public health issue that imposes significant burdens on individuals and society. Although the application of growth fac...

    Authors: Chunhao Zhou, Zhihai Cai, Jialiang Guo, Chengfu Li, Chenghe Qin, Juanwen Yan and Dehong Yang
    Citation: Journal of Nanobiotechnology 2024 22:396
  24. Messenger RNA (mRNA) has emerged as a promising therapeutic molecule with numerous clinical applications in treating central nervous system disorders, tumors, COVID-19, and other diseases. mRNA therapies must ...

    Authors: Zoya Iqbal, Khurrum Rehman, Ayesha Mahmood, Maryam Shabbir, Yujie Liang, Li Duan and Hui Zeng
    Citation: Journal of Nanobiotechnology 2024 22:395
  25. DNA nanostructures have long been developed for biomedical purposes, but their controlled delivery in vivo proposes a major challenge for disease theranostics. We previously reported that DNA nanostructures on...

    Authors: Hao Wang, Li Wen, Hao Wei, Yangmeihui Song, Wenyu Song, Mengting Li, Xiaoli Lan, Weibo Cai and Dawei Jiang
    Citation: Journal of Nanobiotechnology 2024 22:394
  26. The therapeutic strategies for acute ischemic stroke were faced with substantial constraints, emphasizing the necessity to safeguard neuronal cells during cerebral ischemia to reduce neurological impairments a...

    Authors: Yitong Liang, Tingting Fan, Min Bai, Na Cui, Wangting Li, Jingwen Wang and Yue Guan
    Citation: Journal of Nanobiotechnology 2024 22:393
  27. Pancreatic cancer, predominantly pancreatic ductal adenocarcinoma (PDAC), remains a highly lethal malignancy with limited therapeutic options and a dismal prognosis. By targeting the underlying molecular abnor...

    Authors: Li Wang, Qunyan Yao, Xuerui Guo, Bingmei Wang, Jingyi Si, Xingye Wang, Shisong Jing, Ming Yan, Yan Shi, Guangqi Song, Xizhong Shen, Jiyu Guan, Yicheng Zhao and Changfeng Zhu
    Citation: Journal of Nanobiotechnology 2024 22:392
  28. Prostate cancer (PCa) has a high incidence in men worldwide, and almost all PCa patients progress to the androgen-independent stage which lacks effective treatment measures. PTENP1, a long non-coding RNA, has ...

    Authors: Shunye Su, Leyi Liu, Qingfeng Fu, Minghao Ma, Na Yang, Ting Pan, Shengyong Geng, Xue-Feng Yu and Jianqiang Zhu
    Citation: Journal of Nanobiotechnology 2024 22:391
  29. Zinc oxide nanoparticle (ZnO NP) is one of the metal nanomaterials with extensive use in many fields such as feed additive and textile, which is an emerging threat to human health due to widely distributed in ...

    Authors: Guangyu Liu, Jing Lv, Yifan Wang, Kaikai Sun, Huimin Gao, Yuanyou Li, Qichun Yao, Lizhu Ma, Gulzat Kochshugulova and Zhongliang Jiang
    Citation: Journal of Nanobiotechnology 2024 22:390
  30. Nanotechnology holds revolutionary potential in the field of agriculture, with zinc oxide nanoparticles (ZnO NPs) demonstrating advantages in promoting crop growth. Enhanced photosynthetic efficiency is closel...

    Authors: Hao Chen, Yujie Song, Yu Wang, Huan Wang, Zhaotang Ding and Kai Fan
    Citation: Journal of Nanobiotechnology 2024 22:389
  31. Porcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent swine pathogen, which has caused adverse impact on the global swine industry for almost 30 years. However, due to the immune suppressi...

    Authors: Haotian Yang, Meiqi Sun, He Qiu, Huiling Xu, Zhuofan Deng, Han Gu, Nan Wang, Liuyang Du, Fushan Shi, Jiyong Zhou and Fang He
    Citation: Journal of Nanobiotechnology 2024 22:388
  32. Gene therapy is a therapeutic option for mitigating diseases that do not respond well to pharmacological therapy. This type of therapy allows for correcting altered and defective genes by transferring nucleic ...

    Authors: Nazila Valatabar, Fatemeh Oroojalian, Mina Kazemzadeh, Amir Ali Mokhtarzadeh, Reza Safaralizadeh and Amirhossein Sahebkar
    Citation: Journal of Nanobiotechnology 2024 22:386
  33. Numerous studies have confirmed the involvement of extracellular vesicles (EVs) in various physiological processes, including cellular death and tissue damage. Recently, we reported that EVs derived from ische...

    Authors: Xuan Liu, Qingshu Meng, Shanshan Shi, Xuedi Geng, Enhao Wang, Yinzhen Li, Fang Lin, Xiaoting Liang, Xiaoling Xi, Wei Han, Huimin Fan and Xiaohui Zhou
    Citation: Journal of Nanobiotechnology 2024 22:385
  34. Diabetic wounds present significant challenges, specifically in terms of bacterial infection and delayed healing. Therefore, it is crucial to address local bacterial issues and promote accelerated wound healin...

    Authors: Jinlang Fu, Ding Wang, Zinan Tang, Yixin Xu, Jiajun Xie, Rong Chen, Pinkai Wang, Qiang Zhong, Yanhong Ning, Mingyuan Lei, Huaming Mai, Hao Li, Haibing Liu, Jian Wang and Hao Cheng
    Citation: Journal of Nanobiotechnology 2024 22:384
  35. The characteristic features of the rheumatoid arthritis (RA) microenvironment are synovial inflammation and hyperplasia. Therefore, there is a growing interest in developing a suitable therapeutic strategy for...

    Authors: Ye Lin, Yuanyuan Tang, Ouyang Yi, Junping Zhu, Zhaoli Su, Gejing Li, Hua Zhou, Liang Liu, Bin Liu and Xiong Cai
    Citation: Journal of Nanobiotechnology 2024 22:383
  36. Reperfusion therapy is critical for saving heart muscle after myocardial infarction, but the process of restoring blood flow can itself exacerbate injury to the myocardium. This phenomenon is known as myocardi...

    Authors: Wan-ting Meng, Jing Zhu, Ya-chao Wang, Chang-le Shao, Xiu-ya Li, Ping-ping Lu, Meng-ying Huang, Fang-fang Mou, Hai-dong Guo and Guang Ji
    Citation: Journal of Nanobiotechnology 2024 22:382
  37. Hepatocellular carcinoma (HCC) is among the most common malignancies worldwide and is characterized by high rates of morbidity and mortality, posing a serious threat to human health. Interventional embolizatio...

    Authors: Xiaoying Xu, Yu Liu, Yanyan Liu, Yahan Yu, Mingqi Yang, Ligong Lu, Leung Chan and Bing Liu
    Citation: Journal of Nanobiotechnology 2024 22:381
  38. Lipid nanoparticles (LNPs) have proven themselves as transformative actors in chimeric antigen receptor (CAR) T cell therapy, surpassing traditional methods and addressing challenges like immunogenicity, reduc...

    Authors: Muhammad Babar Khawar, Ali Afzal, Yue Si and Haibo Sun
    Citation: Journal of Nanobiotechnology 2024 22:380
  39. The whole-cell inorganic-biohybrid systems show special functions and wide potential in biomedical application owing to the exceptional interactions between microbes and inorganic materials. However, the hybri...

    Authors: Shiyuan Hua, Jun Zhao, Lin Li, Chaoyi Liu, Lihui Zhou, Kun Li, Quan Huang, Min Zhou and Kai Wang
    Citation: Journal of Nanobiotechnology 2024 22:379
  40. Tissue engineered heart valves (TEHVs) demonstrates the potential for tissue growth and remodel, offering particular benefit for pediatric patients. A significant challenge in designing functional TEHV lies in...

    Authors: Chao Xu, Kun Yang, Yin Xu, Xiangfu Meng, Ying Zhou, Yanping Xu, Xueyao Li, Weihua Qiao, Jiawei Shi, Donghui Zhang, Jianglin Wang, Weilin Xu, Hongjun Yang, Zhiqiang Luo and Nianguo Dong
    Citation: Journal of Nanobiotechnology 2024 22:378
  41. Efficient monitoring of glucose concentration in the human body necessitates the utilization of electrochemically active sensing materials in nonenzymatic glucose sensors. However, prevailing limitations such ...

    Authors: Yuanyuan Li, Yi Duan, Jiangtao Lin, Jinghan Liao, Chao Xu, Fangqin Xue and Yourong Duan
    Citation: Journal of Nanobiotechnology 2024 22:377
  42. As an emerging cancer treatment strategy, reactive oxygen species-based tumor catalytic therapies face enormous challenges due to hypoxia and the overexpression of glutathione (GSH) in the tumor microenvironme...

    Authors: Yaping Wang, Xun Zhang, Yunfeng Ma, Xiaobo Zhou, Weijun Xu, Sida Qin and Chengcheng Yang
    Citation: Journal of Nanobiotechnology 2024 22:375
  43. The use of stem cell-derived exosomes (Exos) as therapeutic vehicles is receiving increasing attention. Exosome administration has several advantages over cell transplantation, thus making exosomes promising c...

    Authors: Liming Wang, Jun Chen, Jia Song, Yingyue Xiang, Mengmeng Yang, Longqing Xia, Jingwen Yang, Xinguo Hou, Li Chen and Lingshu Wang
    Citation: Journal of Nanobiotechnology 2024 22:373

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