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  1. Electrical stimulation (ES) is considered a promising therapy for chronic wounds via conductive dressing. However, the lack of a clinically suitable conductive dressing is a serious challenge. In this study, a...

    Authors: Weijing Fan, Xiao Yang, Xiaoming Hu, Renyan Huang, Hongshuo Shi and Guobin Liu
    Citation: Journal of Nanobiotechnology 2024 22:258
  2. Imperceptible examination and unideal treatment effect are still intractable difficulties for the clinical treatment of pancreatic ductal adenocarcinoma (PDAC). At present, despite 5-fluorouracil (5-FU), as a ...

    Authors: Manxiu Huai, Yingjie Wang, Junhao Li, Jiaxing Pan, Fang Sun, Feiyu Zhang, Yi Zhang and Leiming Xu
    Citation: Journal of Nanobiotechnology 2024 22:257
  3. Gastric cancer represents a highly lethal malignancy with an elevated mortality rate among cancer patients, coupled with a suboptimal postoperative survival prognosis. Nectin-4, an overexpressed oncological ta...

    Authors: Yue Wu, Min Zhu, Baihe Sun, Yongting Chen, Yuping Huang, Junwei Gai, Guanghui Li, Yanfei Li, Yakun Wan and Linlin Ma
    Citation: Journal of Nanobiotechnology 2024 22:256
  4. Age is the most important risk factor in degenerative diseases such as osteoarthritis (OA), which is associated with the accumulation of senescent cells in the joints. Here, we aimed to assess the impact of se...

    Authors: Boulestreau Jérémy, Maumus Marie, Bertolino M. Giuliana, Toupet Karine, Jorgensen Christian and Noël Danièle
    Citation: Journal of Nanobiotechnology 2024 22:255
  5. The antifungal activity was studied on sessile and persister cells (PCs) of Candida tropicalis biofilms of gold nanoparticles (AuNPs) stabilized with cetyltrimethylammonium bromide (CTAB-AuNPs) and those conjugat...

    Authors: M. A. Dasilva, K. F. Crespo Andrada, M. Maldonado Torales, I. Manrrique Hughes, P. Pez, J. C. García-Martínez and María Gabriela Paraje
    Citation: Journal of Nanobiotechnology 2024 22:254
  6. Improving cancer therapy by targeting the adverse tumor microenvironment (TME) rather than the cancer cells presents a novel and potentially effective strategy. In this study, we introduced FexMoyS nanoparticles ...

    Authors: Zhilong Yu, Chenyi Wang, Yingjiang Ye, Shan Wang and Kewei Jiang
    Citation: Journal of Nanobiotechnology 2024 22:253
  7. With increasing proportion of the elderly in the population, age-related diseases (ARD) lead to a considerable healthcare burden to society. Prevention and treatment of ARD can decrease the negative impact of ...

    Authors: Yun Dai, Yifan Guo, Weicheng Tang, Dan Chen, Liru Xue, Ying Chen, Yican Guo, Simin Wei, Meng Wu, Jun Dai and Shixuan Wang
    Citation: Journal of Nanobiotechnology 2024 22:252
  8. Hypothermia is a promising therapy for traumatic brain injury (TBI) in the clinic. However, the neuroprotective outcomes of hypothermia-treated TBI patients in clinical studies are inconsistent due to several ...

    Authors: Yuhan Han, Zhengzhong Han, Xuyang Huang, Shanshan Li, Guoliang Jin, Junfeng Feng, Decheng Wu and Hongmei Liu
    Citation: Journal of Nanobiotechnology 2024 22:251
  9. The complexity of repairing large segment defects and eradicating residual tumor cell puts the osteosarcoma clinical management challenging. Current biomaterial design often overlooks the crucial role of preci...

    Authors: Yan Xu, Chao Xu, Huan Song, Xiaobo Feng, Liang Ma, Xiaoguang Zhang, Gaocai Li, Congpu Mu, Lei Tan, Zhengdong Zhang, Zhongyuan Liu, Zhiqiang Luo and Cao Yang
    Citation: Journal of Nanobiotechnology 2024 22:250
  10. Chemotherapy, the mainstay treatment for metastatic cancer, presents serious side effects due to off-target exposure. In addition to the negative impact on patients’ quality of life, side effects limit the dos...

    Authors: Eva Romaní -Cubells, Samuel Martínez-Erro, Victoria Morales, Ana Chocarro-Calvo, José M. García-Martínez, Raúl Sanz, Custodia García-Jiménez and Rafael A. García-Muñoz
    Citation: Journal of Nanobiotechnology 2024 22:249
  11. The use of nanomaterials in medicine offers multiple opportunities to address neurodegenerative disorders such as Alzheimer's and Parkinson's disease. These diseases are a significant burden for society and th...

    Authors: Andreas Tapia-Arellano, Pablo Cabrera, Elizabeth Cortés-Adasme, Ana Riveros, Natalia Hassan and Marcelo J. Kogan
    Citation: Journal of Nanobiotechnology 2024 22:248
  12. Tyrosine kinase inhibitors have been the standard treatment for patients with Philadelphia chromosome-positive (Ph+) leukemia. However, a series of issues, including drug resistance, relapse and intolerance, are ...

    Authors: Yanzi Sun, Yishu Wang, Chunyan Liu, Yingshuang Huang, Qiulin Long, Caoyun Ju, Can Zhang and Yijun Chen
    Citation: Journal of Nanobiotechnology 2024 22:247
  13. Excessive production of reactive oxygen species (ROS) and inflammation are the key problems that impede diabetic wound healing. In particular, dressings with ROS scavenging capacity play a crucial role in the ...

    Authors: Fupeng Li, Zhiyuan Mao, Yun Du, Yuehan Cui, Shengbing Yang, Kai Huang, Jian Yang, Zhuoyuan Li, Yihao Liu, Jinlou Gu, Danru Wang and Chen Wang
    Citation: Journal of Nanobiotechnology 2024 22:246
  14. The general sluggish clearance kinetics of functional inorganic nanoparticles tend to raise potential biosafety concerns for in vivo applications. Renal clearance is a possible elimination pathway for function...

    Authors: Can Chen, Baoxing Huang, Ruru Zhang, Chaoping Sun, Lei Chen, Jianxian Ge, Dandan Zhou, Yueping Li, Shuwang Wu, Zhiyuan Qian, Jianfeng Zeng and Mingyuan Gao
    Citation: Journal of Nanobiotechnology 2024 22:245
  15. Biomaterials can modulate the local immune microenvironments to promote peripheral nerve regeneration. Inspired by the spatial orderly distribution and endogenous electric field of nerve fibers, we aimed to in...

    Authors: Yiting Sun, Yinglong Zhang, Yibo Guo, Dongming He, Wanlin Xu, Wei Fang, Chenping Zhang, Yi Zuo and Zhen Zhang
    Citation: Journal of Nanobiotechnology 2024 22:244
  16. Hepatocellular carcinoma (HCC) represents one of the deadliest cancers globally, making the search for more effective diagnostic and therapeutic approaches particularly crucial. Aptamer-functionalized nanomate...

    Authors: Xiujuan Yin, Jing Rong, Min Shao, Saisai Zhang, Likang Yin, Zhenqiang He and Xiao Wang
    Citation: Journal of Nanobiotechnology 2024 22:243
  17. Two-dimensional ultrathin Ti3C2 (MXene) nanosheets have gained significant attention in various biomedical applications. Although previous studies have described the accumulation and associated damage of Ti3C2 na...

    Authors: Limei Yang, Zhiting He, Le Hu, Hongyu Tang, Yanqing Geng, Qiaoyan Tan, Yue Zhang, Yixian Wen, Wei Wu, Huayan Gu and Xueqing Liu
    Citation: Journal of Nanobiotechnology 2024 22:242
  18. Colorectal cancer (CRC) incidence is increasing in recent years due to intestinal flora imbalance, making oral probiotics a hotspot for research. However, numerous studies related to intestinal flora regulatio...

    Authors: Nannan Li, Lili Niu, Yao Liu, Yang Wang, Xiaomin Su, Ce Xu, Zanya Sun, Huishu Guo, Jingru Gong and Shun Shen
    Citation: Journal of Nanobiotechnology 2024 22:241
  19. Zinc oxide nanoparticles (ZnO NPs) stand as among the most significant metal oxide nanoparticles in trigger the formation of reactive oxygen species (ROS) and induce apoptosis. Nevertheless, the utilization of...

    Authors: Shuqing Dong, Yuqi Huang, Hanrong Yan, Huarong Tan, Liying Fan, Minghao Chao, Yiping Ren, Ming Guan, Jiaxin Zhang, Zhao Liu and Fenglei Gao
    Citation: Journal of Nanobiotechnology 2024 22:240
  20. Widespread distribution of porcine epidemic diarrhea virus (PEDV) has led to catastrophic losses to the global pig farming industry. As a result, there is an urgent need for rapid, sensitive and accurate tests...

    Authors: Xiao Hu, Mengjia Zhang, Yiwei Liu, Yu-Tao Li, Wentao Li, Tingxian Li, Jiahao Li, Xueqian Xiao, Qigai He, Zhi-Yong Zhang and Guo-Jun Zhang
    Citation: Journal of Nanobiotechnology 2024 22:239
  21. Myeloid-derived suppressor cells (MDSCs) promote tumor growth, metastasis, and lead to immunotherapy resistance. Studies revealed that miRNAs are also expressed in MDSCs and promote the immunosuppressive funct...

    Authors: Jingxia Han, Rong Qin, Shaoting Zheng, Xiaohui Hou, Xiaorui Wang, Huihui An, Zhongwei Li, Yinan Li, Heng Zhang, Denghui Zhai, Huijuan Liu, Jing Meng and Tao Sun
    Citation: Journal of Nanobiotechnology 2024 22:237
  22. Increased proinflammatory cytokines and infiltration of inflammatory cells in the stroma are important pathological features of type IIIA chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS-A), and the i...

    Authors: Guojing Song, Fuhan Zhao, Rongrong Ni, Bingqian Deng, Saipeng Chen, Ruimin Hu, Jun Zheng, Yiji Peng, Heting Liu, Yang Luo, Zhansong Zhou, Gang Huang and Wenhao Shen
    Citation: Journal of Nanobiotechnology 2024 22:236
  23. Different from most of the conventional platforms with dissatisfactory theranostic capabilities, supramolecular nanotheranostic systems have unparalleled advantages via the artful combination of supramolecular...

    Authors: Dan Wu, Jianfeng Wang, Xianlong Du, Yibin Cao, Kunmin Ping and Dahai Liu
    Citation: Journal of Nanobiotechnology 2024 22:235
  24. Radiotherapy-induced immune activation holds great promise for optimizing cancer treatment efficacy. Here, we describe a clinically used radiosensitizer hafnium oxide (HfO2) that was core coated with a MnO2 shell...

    Authors: Honglei Hu, Shuting Zheng, Chenxi He, Yinfei Zheng, Qiming Wei, Siwen Chen, Zede Wu, Yikai Xu, Bingxia Zhao and Chenggong Yan
    Citation: Journal of Nanobiotechnology 2024 22:234
  25. Dry Eye Disease (DED) is a prevalent multifactorial ocular disease characterized by a vicious cycle of inflammation, oxidative stress, and mitochondrial dysfunction on the ocular surface, all of which lead to ...

    Authors: Yuanyou Xia, Yu Zhang, Yangrui Du, Zhigang Wang, Long Cheng and Zhiyu Du
    Citation: Journal of Nanobiotechnology 2024 22:233
  26. Intra-articular drugs used to treat osteoarthritis (OA) often suffer from poor pharmacokinetics and stability. Nano-platforms as drug delivery systems for drug delivery are promising for OA therapy. In this st...

    Authors: Lanli Huang, Yi Yao, Zhuren Ruan, Shengqing Zhang, Xianjing Feng, Chun Lu, Jinmin Zhao, Feiying Yin, Cunwei Cao and Li Zheng
    Citation: Journal of Nanobiotechnology 2024 22:221
  27. Excess free radicals at the wound site can cause an inflammatory response, which is not conducive to wound healing. Hydrogels with antioxidant properties can prevent inflammatory storms by scavenging free radi...

    Authors: Xiaoyi Zheng, Yongliang Ouyang, Hengwei Fan, Liying Zhang, Shige Wang, Yanbo Zeng, Lianghao Hu and Jiulong Zhao
    Citation: Journal of Nanobiotechnology 2024 22:217
  28. Diabetic wounds pose a challenge to healing due to increased bacterial susceptibility and poor vascularization. Effective healing requires simultaneous bacterial and biofilm elimination and angiogenesis stimul...

    Authors: Jiajun Xie, Guihua Liu, Rong Chen, Ding Wang, Huaming Mai, Qiang Zhong, Yanhong Ning, Jinlang Fu, Zinan Tang, Yixin Xu, Hao Li, Mingyuan Lei, Hao Cheng, Yuliang Huang and Yang Zhang
    Citation: Journal of Nanobiotechnology 2024 22:232
  29. Circulating tumor cells (CTCs) are considered as a useful biomarker for early cancer diagnosis, which play a crucial role in metastatic process. Unfortunately, the tumor heterogeneity and extremely rare occurr...

    Authors: Xinbang Jiang, Xiangyun Zhang, Chen Guo, Zhuang Liu, Xiaofang Guo, Ziying Tian, Zimeng Wang, Jingxuan Yang, Xinglu Huang and Lailiang Ou
    Citation: Journal of Nanobiotechnology 2024 22:231
  30. Tumor vaccines, a crucial immunotherapy, have gained growing interest because of their unique capability to initiate precise anti-tumor immune responses and establish enduring immune memory. Injected tumor vac...

    Authors: Yongchao Zha, Li Fu, Zonghua Liu, Jiansheng Lin and Linghong Huang
    Citation: Journal of Nanobiotechnology 2024 22:230
  31. Efficiently removing excess reactive oxygen species (ROS) generated by various factors on the ocular surface is a promising strategy for preventing the development of dry eye disease (DED). The currently avail...

    Authors: Wei Zhang, Mengyang Zhao, Dandan Chu, Huiying Chen, Bingbing Cui, Qingyun Ning, Xing Wang, Zhanrong Li, Shaokui Cao and Jingguo Li
    Citation: Journal of Nanobiotechnology 2024 22:229
  32. Development of ferroptosis-inducible nanoplatforms with high efficiency and specificity is highly needed and challenging in tumor ferrotherapy. Here, we demonstrate highly effective tumor ferrotherapy using ir...

    Authors: Panpan Xue, Huilan Zhuang, Tingjie Bai, Xuemei Zeng, Jinpeng Deng, Sijie Shao and Shuangqian Yan
    Citation: Journal of Nanobiotechnology 2024 22:228
  33. Elevated interstitial fluid pressure within tumors, resulting from impaired lymphatic drainage, constitutes a critical barrier to effective drug penetration and therapeutic outcomes.

    Authors: Xuwu Zhang, Xinyue Zhang, Shiqi Liu, Weidong Zhang, Liang Dai, Xifa Lan, Desong Wang, Wenkang Tu, Yuchu He and Dawei Gao
    Citation: Journal of Nanobiotechnology 2024 22:227
  34. Nanozyme, characterized by outstanding and inherent enzyme-mimicking properties, have emerged as highly promising alternatives to natural enzymes owning to their exceptional attributes such as regulation of ox...

    Authors: Yanan Wang, Xiaoyun He, Kunlun Huang and Nan Cheng
    Citation: Journal of Nanobiotechnology 2024 22:226
  35. Immunogenic cell death (ICD) plays a crucial role in triggering the antitumor immune response in the tumor microenvironment (TME). Recently, considerable attention has been dedicated to ferroptosis, a type of ...

    Authors: Zihan Deng, Binghui Li, Muyang Yang, Lisen Lu, Xiujuan Shi, Jonathan F. Lovell, Xiantao Zeng, Weidong Hu and Honglin Jin
    Citation: Journal of Nanobiotechnology 2024 22:225
  36. Poorly identified tumor boundaries and nontargeted therapies lead to the high recurrence rates and poor quality of life of prostate cancer patients. Near-infrared-II (NIR-II) fluorescence imaging provides cert...

    Authors: Chenchen Liu, Zong Chang, Kailei Chen, Qiang Xue, Bingxin Shu, Zhihao Wei, Xuan Zhou, Like Guo, Yuling Zhang, Yingying Pan, Qi Cao, Huageng Liang, Qinchao Sun and Xiaoping Zhang
    Citation: Journal of Nanobiotechnology 2024 22:224
  37. Cardiac muscle targeting is a notoriously difficult task. Although various nanoparticle (NP) and adeno-associated viral (AAV) strategies with heart tissue tropism have been developed, their performance remains...

    Authors: Lauren Switala, Lin Di, Huiyun Gao, Courteney Asase, Matthew Klos, Palanivel Rengasamy, Daria Fedyukina and Andrei Maiseyeu
    Citation: Journal of Nanobiotechnology 2024 22:223
  38. Aging is a very complex physiological phenomenon, and sEVs are involved in the regulation of this mechanism. Serum samples from healthy individuals under 30 and over 60 years of age were collected to analyze d...

    Authors: Nannan Ning, Jianying Lu, Qianpeng Li, Mengmeng Li, Yanling Cai, Hongchun Wang and Jingxin Li
    Citation: Journal of Nanobiotechnology 2024 22:222
  39. Bone marrow mesenchymal stem cells (BMSCs) can differentiate into Schwann cells (SCs) during peripheral nerve injury; in our previous research, we showed that SC-derived exosomes (SC-exos) played a direct indu...

    Authors: Xianxiang Zhang, Weiwei Zhang, Hao Sun and Hui Wang
    Citation: Journal of Nanobiotechnology 2024 22:220
  40. Adipose-derived stem cells (ASCs) represent the most advantageous choice for soft tissue regeneration. Studies proved the recruitment of ASCs post tissue injury was mediated by chemokine CXCL12, but the mechan...

    Authors: Yunzi Chen, Ye Li, Bin Li, Delin Hu, Ziqing Dong and Feng Lu
    Citation: Journal of Nanobiotechnology 2024 22:219
  41. Approximately 80 percent of the total RNA in cells is ribosomal RNA (rRNA), making it an abundant and inexpensive natural source of long, single-stranded nucleic acid, which could be used as raw material for t...

    Authors: Anastasia Shapiro, Noah Joseph, Nadav Mellul, Almogit Abu-Horowitz, Boaz Mizrahi and Ido Bachelet
    Citation: Journal of Nanobiotechnology 2024 22:218
  42. The enhanced permeability and retention (EPR) effect has become the guiding principle for nanomedicine against cancer for a long time. However, several biological barriers severely resist therapeutic agents’ p...

    Authors: Jiaojiao Li, Dandan Mi, Rujing Wang, Yuke Li, Mengnan Zhao and Sanjun Shi
    Citation: Journal of Nanobiotechnology 2024 22:216
  43. Stem cells (SCs) have been used therapeutically for decades, yet their applications are limited by factors such as the risk of immune rejection and potential tumorigenicity. Extracellular vesicles (EVs), a key...

    Authors: Wenya Chen, Peipei Wu, Can Jin, Yinjie Chen, Chong Li and Hui Qian
    Citation: Journal of Nanobiotechnology 2024 22:215
  44. Combination of tumor immunotherapy with photothermal therapy (PTT) is a feasible tactic to overcome the drawback of immunotherapy such as poor immune response. Via triggering the immunogenic cells death (ICD), PT...

    Authors: Tan Li, Xingyu Zhang, Chengyu Shi, Qiao Liu and Yuetao Zhao
    Citation: Journal of Nanobiotechnology 2024 22:214
  45. The main issues faced during the treatment of apical periodontitis are the management of bacterial infection and the facilitation of the repair of alveolar bone defects to shorten disease duration. Conventiona...

    Authors: Youyun Zeng, Xiangyu Hu, Zhibin Cai, Dongchao Qiu, Ying Ran, Yiqin Ding, Jiayi Shi, Xiaojun Cai and Yihuai Pan
    Citation: Journal of Nanobiotechnology 2024 22:213
  46. Osteoporosis is a highly prevalent metabolic disease characterized by low systemic bone mass and deterioration of bone microarchitecture, resulting in reduced bone strength and increased fracture risk. Current...

    Authors: Weihang Gao, Jiao Jiao Li, Jingyu Shi, Hongbing Lan, Yuanyuan Guo and Dehao Fu
    Citation: Journal of Nanobiotechnology 2024 22:212
  47. The development of innovative wound dressing materials is crucial for effective wound care. It’s an active area of research driven by a better understanding of chronic wound pathogenesis. Addressing wound care...

    Authors: Naveen Palani, Pradeshwaran Vijayakumar, P. Monisha, Saravanakumar Ayyadurai and Suriyaprakash Rajadesingu
    Citation: Journal of Nanobiotechnology 2024 22:211
  48. Carbon dots (CDs) are novel carbon-based nanomaterials that have been used as photosensitizer-mediated photodynamic therapy (PDT) in recent years due to their good photosensitizing activity. Photosensitizers (...

    Authors: Lingxiang Sun, Yifan Zhao, Hongyi Peng, Jian Zhou, Qingmei Zhang, Jingyu Yan, Yingyu Liu, Susu Guo, Xiuping Wu and Bing Li
    Citation: Journal of Nanobiotechnology 2024 22:210
  49. Bone marrow mesenchymal stem cells (BMSCs) can undergo inadequate osteogenesis or excessive adipogenesis as they age due to changes in the bone microenvironment, ultimately resulting in decreased bone density ...

    Authors: Zhen-Xing Wang, Xiao Lin, Jia Cao, Yi-Wei Liu, Zhong-Wei Luo, Shan-Shan Rao, Qiang Wang, Yi-Yi Wang, Chun-Yuan Chen, Guo-Qiang Zhu, Fu-Xing-Zi Li, Yi-Juan Tan, Yin Hu, Hao Yin, You-You Li, Ze-Hui He…
    Citation: Journal of Nanobiotechnology 2024 22:208

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