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  1. Nanoinjection—the process of intracellular delivery using vertically configured nanostructures—is a physical route that efficiently negotiates the plasma membrane, with minimal perturbation and toxicity to the...

    Authors: Ali-Reza Shokouhi, Yaping Chen, Hao Zhe Yoh, Takahide Murayama, Koukou Suu, Yasuhiro Morikawa, Jason Brenker, Tuncay Alan, Nicolas H. Voelcker and Roey Elnathan
    Citation: Journal of Nanobiotechnology 2023 21:273
  2. Gene therapy holds great promise for treating a multitude of inherited and acquired diseases by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit manipulation of gene...

    Authors: Chenfei Wang, Chaolan Pan, Haiyang Yong, Feifei Wang, Tao Bo, Yitong Zhao, Bin Ma, Wei He and Ming Li
    Citation: Journal of Nanobiotechnology 2023 21:272
  3. The development of atherosclerosis (AS) is closely linked to changes in the plaque microenvironment, which consists primarily of the cells that form plaque and the associated factors they secrete. The onset of...

    Authors: Chengxi Wu, Jingying Mao, Xueqin Wang, Ronghao Yang, Chenglong Wang, Chunhong Li and Xiangyu Zhou
    Citation: Journal of Nanobiotechnology 2023 21:271
  4. Implant infections caused by biofilm forming bacteria are a major threat in orthopedic surgery. Delivering antibiotics directly to an implant affected by a bacterial biofilm via superparamagnetic nanoporous si...

    Authors: Andras Polyak, Heidi Harting, Nina Angrisani, Timo Herrmann, Nina Ehlert, Jessica Meißner, Michael Willmann, Silav Al-Bazaz, Tobias L. Ross, Jens P. Bankstahl and Janin Reifenrath
    Citation: Journal of Nanobiotechnology 2023 21:270
  5. Successful biomaterial implantation requires appropriate immune responses. Macrophages are key mediators involved in this process. Currently, exploitation of the intrinsic properties of biomaterials to modulat...

    Authors: Yiming Ren, Yi Chen, Wei Chen, Haotian Deng, Peiqi Li, Yubo Liu, Cangjian Gao, Guangzhao Tian, Chao Ning, Zhiguo Yuan, Xiang Sui, Shuyun Liu and Quanyi Guo
    Citation: Journal of Nanobiotechnology 2023 21:269
  6. Scar formation is a common physiological process that occurs after injury, but in some cases, pathological scars can develop, leading to serious physiological and psychological effects. Unfortunately, there ar...

    Authors: Jia-Ying Ding, Lu Sun, Zhi-Heng Zhu, Xi-Chen Wu, Xiao-Ling Xu and Yan-Wei Xiang
    Citation: Journal of Nanobiotechnology 2023 21:268
  7. Graphene-based nanomaterials have attracted significant attention in the field of nanomedicine due to their unique atomic arrangement which allows for manifold applications. However, their inherent high hydrop...

    Authors: Erica Quagliarini, Daniela Pozzi, Francesco Cardarelli and Giulio Caracciolo
    Citation: Journal of Nanobiotechnology 2023 21:267
  8. Bacterial infections can significantly impede wound healing and pose a serious threat to the patient’s life. The excessive use of antibiotics to combat bacterial infections has led to the emergence of multi-dr...

    Authors: Ye Guo, Bingqing Xie, Min Jiang, Lingling Yuan, Xueyu Jiang, Silei Li, Rui Cai, Junliang Chen, Xia Jiang, Yun He and Gang Tao
    Citation: Journal of Nanobiotechnology 2023 21:266
  9. Emerging ferroptosis-driven therapies based on nanotechnology function either by increasing intracellular iron level or suppressing glutathione peroxidase 4 (GPX4) activity. Nevertheless, the therapeutic strat...

    Authors: Zhiping Rao, Yutian Xia, Qian Jia, Yutong Zhu, Lexuan Wang, Guohuan Liu, Xuelan Liu, Peng Yang, Pengbo Ning, Ruili Zhang, Xianghan Zhang, Chaoqiang Qiao and Zhongliang Wang
    Citation: Journal of Nanobiotechnology 2023 21:265
  10. ZIF-8 may experience ion-responsive degradation in ionic solutions, which will change its initial architecture and restrict its direct biological use. Herein, we report an abnormal phenomenon in which ZIF-8 in...

    Authors: Bingqian Wang, Yuyang Zeng, Shaokai Liu, Muran Zhou, Huimin Fang, Zhenxing Wang and Jiaming Sun
    Citation: Journal of Nanobiotechnology 2023 21:264
  11. Oral administration is preferred over other drug delivery methods due to its safety, high patient compliance, ease of ingestion without discomfort, and tolerance of a wide range of medications. However, oral d...

    Authors: Yang-Bao Miao, Tianxing Xu, Ying Gong, Anmei Chen, Liang Zou, Tao Jiang and Yi Shi
    Citation: Journal of Nanobiotechnology 2023 21:263
  12. Authors: Yapeng Lu, Meihui Zhao, Ye Peng, Sizhe He, Xiaopeng Zhu, Chao Hu, Guanghua Xia, Tao Zuo, Xueying Zhang, Yonghuan Yun, Weimin Zhang and Xuanri Shen
    Citation: Journal of Nanobiotechnology 2023 21:262

    The original article was published in Journal of Nanobiotechnology 2022 20:426

  13. The development of natural membranes as coatings for nanoparticles to traverse the blood-brain barrier (BBB) presents an effective approach for treating central nervous system (CNS) disorders. In this study, w...

    Authors: Yue Hu, Min Zhao, Hui Wang, Yang Guo, Xiaolan Cheng, Tong Zhao, Hanqing Wang, Yafeng Zhang, Yong Ma and Weiwei Tao
    Citation: Journal of Nanobiotechnology 2023 21:261
  14. Thrombotic vascular disorders, specifically thromboembolisms, have a significant detrimental effect on public health. Despite the numerous thrombolytic and antithrombotic drugs available, their efficacy in pen...

    Authors: Chia-Hung Liu, Pei-Ru Jheng, Lekha Rethi, Chandraiah Godugu, Ching Yi Lee, Yan-Ting Chen, Hieu Trung Nguyen and Er-Yuan Chuang
    Citation: Journal of Nanobiotechnology 2023 21:260
  15. Autogenous bone grafting has long been considered the gold standard for treating critical bone defects. However, its use is plagued by numerous drawbacks, such as limited supply, donor site morbidity, and rest...

    Authors: Xiao-Liang Liu, Chuan-Jian Zhang, Jing-Jing Shi, Qin-Fei Ke, Yu-Wei Ge, Zhen-An Zhu and Ya-Ping Guo
    Citation: Journal of Nanobiotechnology 2023 21:259
  16. The development of osteoarthritis (OA) correlates with the expansion of senescent cells in cartilage, which contributes to an inflammatory microenvironment that accelerates matrix degradation and hampers carti...

    Authors: Xianming Wang, Yu Cai, Cuixi Wu, Jiamin Liang, Kangning Tang, Zefeng Lin, Lingling Chen, Yao Lu and Qing Wang
    Citation: Journal of Nanobiotechnology 2023 21:258
  17. Stabilization and increased activity of hypoxia-inducible factor 1-α (HIF-1α) can directly increase cancellous bone formation and play an essential role in bone modeling and remodeling. However, whether an inc...

    Authors: Shuang Song, Guanhua Zhang, Xutao Chen, Jian Zheng, Xiangdong Liu, Yiqing Wang, Zijun Chen, Yuxi Wang, Yingliang Song and Qin Zhou
    Citation: Journal of Nanobiotechnology 2023 21:257
  18. Organophosphate (OP)-induced delayed neurological damage is attributed to permanent neuropathological lesions caused by irreversible OP-neurocyte interactions, without potent brain-targeted etiological antidot...

    Authors: Shuaijun Zou, Qianqian Wang, Qian He, Guoyan Liu, Juxingsi Song, Jie Li, Fan Wang, Yichao Huang, Yanan Hu, Dayuan Zhou, Yongfei Lv, Yuanjie Zhu, Beilei Wang and Liming Zhang
    Citation: Journal of Nanobiotechnology 2023 21:256
  19. The COVID-19 pandemic, which originated in Hubei, China, in December 2019, has had a profound impact on global public health. With the elucidation of the SARS-CoV-2 virus structure, genome type, and routes of ...

    Authors: Yuqing Li, Jingqi Chen, Jinchao Wei, Xueliang Liu, Lu Yu, Linqi Yu, Ding Ding and Yu Yang
    Citation: Journal of Nanobiotechnology 2023 21:255
  20. Lymph nodes targeted drug delivery is an attractive approach to improve cancer immunotherapy outcomes. Currently, the depth of understanding of afferent and efferent arms in brain immunity reveals the potentia...

    Authors: Yangzhi Qi, Wei Xiong, Qianxue Chen, Zhifei Ye, Cailei Jiang, Yan He and Qingsong Ye
    Citation: Journal of Nanobiotechnology 2023 21:254
  21. Inhibition of tumor growth and normalization of immune responses in the tumor microenvironment (TME) are critical issues for improving cancer therapy. However, in the treatment of glioma, effective nanomedicin...

    Authors: Jisu Kim, Ying Zhu, Sunhui Chen, Dongdong Wang, Shuya Zhang, Jiaxuan Xia, Shiyi Li, Qiujun QIU, Hyukjin Lee and Jianxin Wang
    Citation: Journal of Nanobiotechnology 2023 21:253
  22. In recent years, crop production has expanded due to the variety of commercially available species. This increase in production has led to global competition and the search for biostimulant products that impro...

    Authors: Jorge J. O. Garza-García, José A. Hernández-Díaz, Janet M. León-Morales, Gilberto Velázquez-Juárez, Adalberto Zamudio-Ojeda, Jenny Arratia-Quijada, Oscar K. Reyes-Maldonado, Julio C. López-Velázquez and Soledad García-Morales
    Citation: Journal of Nanobiotechnology 2023 21:252
  23. Nano-engineering with unique “custom function” capability has shown great potential in solving technical difficulties of nanomaterials in tumor treatment. Through tuning the size and surface properties control...

    Authors: Yuxin Wang, Shimei Li, Xiangling Ren, Shiping Yu and Xianwei Meng
    Citation: Journal of Nanobiotechnology 2023 21:250
  24. Nanomedicine has emerged as a promising therapeutic approach, but its translation to the clinic has been hindered by the lack of cellular models to anticipate how tumor cells will respond to therapy. Three-dim...

    Authors: Faezeh Vakhshiteh, Zeinab Bagheri, Marziye Soleimani, Akram Ahvaraki, Parisa Pournemat, Seyed Ebrahim Alavi and Zahra Madjd
    Citation: Journal of Nanobiotechnology 2023 21:249
  25. Lymph node metastasis is a frequent occurrence in a variety of tumour forms and poses an enormous challenge to cancer treatment. This process is critical to the development of the disease and is frequently lin...

    Authors: Huan-Rong Lan, You-Ni Zhang, Yue-Jun Han, Shi-Ya Yao, Meng-Xiang Yang, Xiao-Gang Xu, Xiao-Zhou Mou and Ke-Tao Jin
    Citation: Journal of Nanobiotechnology 2023 21:247
  26. Type 2 diabetes mellitus (T2DM) predominantly considered a metabolic disease is now being considered an inflammatory disease as well due to the involvement of meta-inflammation. Obesity-induced adipose tissue ...

    Authors: Kunal Sarkar, Sarbashri Bank, Arindam Chatterjee, Koushik Dutta, Anwesha Das, Santanu Chakraborty, Nirvika Paul, Jit Sarkar, Sriparna De, Sudakshina Ghosh, Krishnendu Acharyya, Dipankar Chattopadhyay and Madhusudan Das
    Citation: Journal of Nanobiotechnology 2023 21:246
  27. Sentinel lymph node (SLN) metastasis is an important promoter of distant metastasis in breast cancer. Therefore, the timely diagnosis and precise treatment are crucial for patient staging and prognosis. Howeve...

    Authors: Yanfeng Dai, Xiang Yu, Yuehong Leng, Xingzhou Peng, Junjie Wang, Yifan Zhao, Juan Chen and Zhihong Zhang
    Citation: Journal of Nanobiotechnology 2023 21:245
  28. Neuroblastoma is one of the common extracranial tumors in children (infants to 2 years), accounting for 8 ~ 10% of all malignant tumors. Few special drugs have been used for clinical treatment currently.

    Authors: Yingnan Jiang, Lizhi Xiao, Jifeng Wang, Tenghui Tian, Guancheng Liu, Yu Zhao, Jiajuan Guo, Wei Zhang, Jiawen Wang, Changbao Chen, Wenyi Gao and Bai Yang
    Citation: Journal of Nanobiotechnology 2023 21:244
  29. Osteosarcoma (OS) is the most prevalent primary malignant bone tumor. However, single-agent chemotherapy exhibits limited efficacy against OS and often encounters tumor resistance. Therefore, we designed and c...

    Authors: Yanlong Xu, Longhai Du, Binxu Han, Yu Wang, Jichang Fei, Kuo Xia, Yonghua Zhai and Zuochong Yu
    Citation: Journal of Nanobiotechnology 2023 21:243
  30. Central serous chorioretinopathy (CSC) is the fourth most prevalent retinal disease leading to age-related macular degeneration (AMD) and retinal atrophy. However, CSC's pathogenesis and therapeutic target nee...

    Authors: Jee Myung Yang, Soo Jin Kim, Seongyeol Park, Wonyung Son, Anna Kim and Junyeop Lee
    Citation: Journal of Nanobiotechnology 2023 21:242
  31. Wound healing is a common occurrence. However, delayed healing and aberrant scarring result in pathological wound healing. Accordingly, a scarless wound healing remains a significant clinical challenge. In thi...

    Authors: Kun Chen, Yuanhu Liu, Xiaohui Liu, Yongli Guo, Jing Liu, Jiaojiao Ding, Zheng Zhang, Xin Ni and Yunsheng Chen
    Citation: Journal of Nanobiotechnology 2023 21:241
  32. Acute myeloid leukemia (AML) is an invasive hematopoietic malignancy caused by excessive proliferation of myeloblasts. Classical chemotherapies and cell transplantation therapies have remarkable efficacy in AM...

    Authors: Yimin Jia, Cun Sun, Ting Chen, Hui Zhu, Tianrui Wang, Yan Ye, Xing Luo, Xiaoqiang Zeng, Yun Yang, Hao Zeng, Quanming Zou, Enqiang Liu, Jieping Li and Hongwu Sun
    Citation: Journal of Nanobiotechnology 2023 21:240
  33. Authors: Yongjun Yang, Shijun Fan, Qian Chen, Yongling Lu, Yuanfeng Zhu, Xiaoli Chen, Lin Xia, Qianying Huang, Jiang Zheng and Xin Liu
    Citation: Journal of Nanobiotechnology 2023 21:239

    The original article was published in Journal of Nanobiotechnology 2022 20:37

  34. Functional hydrogels show potential application in repairing spinal cord injury (SCI) due to their unique chemical, physical, and biological properties and functions. In this comprehensive review, we present r...

    Authors: Zhengang Sun, Danzhu Zhu, Hong Zhao, Jia Liu, Peng He, Xin Luan, Huiqiang Hu, Xuanfen Zhang, Gang Wei and Yongming Xi
    Citation: Journal of Nanobiotechnology 2023 21:238
  35. The stimuli-responsive nanofibers prepared by electrospinning have become an ideal stimuli-responsive material due to their large specific surface area and porosity, which can respond extremely quickly to exte...

    Authors: Kai Chen, Yonghui Li, Youbin Li, Yinfeng Tan, Yingshuo Liu, Weisan Pan and Guoxin Tan
    Citation: Journal of Nanobiotechnology 2023 21:237
  36. Therapeutic tumor vaccines have attracted considerable attention in the past decade; they can induce tumor regression, eradicate minimal residual disease, establish lasting immune memory and avoid non-specific...

    Authors: Ao He, Xiaoye Li, Zhuo Dai, Qiang Li, Yu Zhang, Meng Ding, Zhi-fa Wen, Yongbin Mou and Heng Dong
    Citation: Journal of Nanobiotechnology 2023 21:236
  37. Systemic administration of platinum-based drugs has obvious limitations in the treatment of advanced bladder cancer (BC) owing to lower tumor accumulation and uncontrolled release of chemotherapeutics. There i...

    Authors: Ren Mo, Jianati Dawulieti, Ning Chi, Ziping Wu, Zhizhong Yun, Jianjun Du, Xinhua Li, Junfeng Liu, Xiaochun Xie, Kai Xiao, Fangman Chen, Dan Shao and Kewei Ma
    Citation: Journal of Nanobiotechnology 2023 21:235
  38. The rapid and accurate identification of methicillin-resistant Staphylococcus aureus at an early antibiotic therapy stage would be benefit to disease diagnosis and antibiotic selection. Herein, we integrated cros...

    Authors: Jiangling Wu, Yu Huang, Xiaojuan Ding, Lina Kang, Xiaoliang Wang, Dandan Li, Wei Cheng, Gang Liu, Jianjiang Xue and Shijia Ding
    Citation: Journal of Nanobiotechnology 2023 21:234
  39. The immunosuppressive microenvironment in glioma induces immunotherapy resistance and is associated with poor prognosis. Glioma-associated mesenchymal stem cells (GA-MSCs) play an important role in the formati...

    Authors: Wei Qiu, Qindong Guo, Xiaofan Guo, Chaochao Wang, Boyan Li, Yanhua Qi, Shaobo Wang, Rongrong Zhao, Xiao Han, Hao Du, Shulin Zhao, Ziwen Pan, Yang Fan, Qingtong Wang, Zijie Gao, Gang Li…
    Citation: Journal of Nanobiotechnology 2023 21:233
  40. Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural carriers for therape...

    Authors: Shuang Du, Yucheng Guan, Aihua Xie, Zhao Yan, Sijia Gao, Weirong Li, Lang Rao, Xiaojia Chen and Tongkai Chen
    Citation: Journal of Nanobiotechnology 2023 21:231
  41. The visualization of bone imaging in vivo is of great significance for the understanding of some bone-related diseases or physiological processes. Herein, a bone-targeted NIR-II small molecule (TTQF-SO3), which w...

    Authors: Pengfei Chen, Fan Qu, Liuliang He, Mingfei Li, Pengfei Sun, Quli Fan, Chi Zhang and Daifeng Li
    Citation: Journal of Nanobiotechnology 2023 21:230
  42. The inflammatory immune environment surrounding titanium bone implants determines the formation of osseointegration, and nanopatterning on implant surfaces modulates the immune microenvironment in the implant ...

    Authors: Yiru Fu, Zheng Jing, Tao Chen, Xinxin Xu, Xu Wang, Mingxing Ren, Yanqiu Wu, Tianli Wu, Yuzhou Li, He Zhang, Ping Ji and Sheng Yang
    Citation: Journal of Nanobiotechnology 2023 21:229
  43. Photothermal therapy (PTT) is taken as a promising strategy for cancer therapy, however, its applicability is hampered by cellular thermoresistance of heat shock response and insufficient accumulation of photo...

    Authors: Wen Yang, Ning Wang, Jin Yang, Chao Liu, Shuang Ma, Xiye Wang, Wenzhen Li, Meiling Shen, Qinjie Wu and Changyang Gong
    Citation: Journal of Nanobiotechnology 2023 21:228
  44. Myocardial infarction (MI) resulting from coronary artery occlusion is the leading global cause of cardiovascular disability and mortality. Anti-inflammatory treatment plays an important role in MI treatment. ...

    Authors: Kun Wang, Ke Zhu, Ziyang Zhu, Fuqiang Shao, Ruijie Qian, Chenyang Wang, Haiqing Dong, Yongyong Li, Zairong Gao and Jun Zhao
    Citation: Journal of Nanobiotechnology 2023 21:227
  45. Medial arterial calcification (MAC), a systemic vascular disease different from atherosclerosis, is associated with an increased incidence of cardiovascular events. Several studies have demonstrated that ambie...

    Authors: Fu-Xing-Zi Li, Jun-Jie Liu, Feng Xu, Su-Kang Shan, Ming-Hui Zheng, Li-Min Lei, Xiao Lin, Bei Guo, Chang-Chun Li, Feng Wu, Ke-Xin Tang, Ye-Chi Cao, Yun-Yun Wu, Jia-Yue Duan, Yan-Lin Wu, Si-Yang He…
    Citation: Journal of Nanobiotechnology 2023 21:226

    The Correction to this article has been published in Journal of Nanobiotechnology 2023 21:306

  46. Macrophages polarized to the M2 subtype after spinal cord injury (SCI) are beneficial for promoting neurological recovery. The crosstalk between endothelial cells (ECs) and macrophages is crucial for the imbal...

    Authors: Wei Peng, Yong Xie, Zixiang Luo, Yudong Liu, Jiaqi Xu, Chengjun Li, Tian Qin, Hongbin Lu and Jianzhong Hu
    Citation: Journal of Nanobiotechnology 2023 21:225
  47. Although various new biomaterials have enriched the methods for periodontal regeneration, their efficacy is still controversial, and the regeneration of damaged support tissue in the periodontium remains chall...

    Authors: Xiongcheng Xu, Ziqin Chen, Long Xiao, Yanmei Xu, Nianqi Xiao, Weiqiu Jin, Yuling Chen, Yanfen Li and Kai Luo
    Citation: Journal of Nanobiotechnology 2023 21:223

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