Nio K, Yamashita T, Kaneko S. The evolving concept of liver cancer stem cells. Mol Cancer. 2017;16(1):4.
Article
PubMed
PubMed Central
Google Scholar
Yang JD, Hainaut P, Gores GJ, Amadou A, Plymoth A, Roberts LR. A global view of hepatocellular carcinoma: trends, risk, prevention and management. Nat Rev Gastroenterol Hepatol. 2019;16(10):589–604.
Article
PubMed
PubMed Central
Google Scholar
Refolo MG, Messa C, Guerra V, Carr BI, D’Alessandro R. Inflammatory mechanisms of HCC development. Cancers. 2020;12(3):641.
Article
CAS
PubMed Central
Google Scholar
Sun Q, Zhang Z, Lu Y, Liu Q, Xu X, Xu J, et al. Loss of xanthine oxidoreductase potentiates propagation of hepatocellular carcinoma stem cells. Hepatology. 2020;71(6):2033–49.
Article
CAS
PubMed
Google Scholar
Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet. 2012;379(9822):1245–55.
Article
PubMed
Google Scholar
Fujiwara N, Friedman SL, Goossens N, Hoshida Y. Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine. J Hepatol. 2018;68(3):526–49.
Article
PubMed
Google Scholar
Clouston AD, Powell EE, Walsh MJ, Richardson MM, Demetris AJ, Jonsson JR. Fibrosis correlates with a ductular reaction in hepatitis C: roles of impaired replication, progenitor cells and steatosis. Hepatology. 2005;41(4):809–18.
Article
CAS
PubMed
Google Scholar
Richardson MM, Jonsson JR, Powell EE, Brunt EM, Neuschwander-Tetri BA, Bhathal PS, et al. Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction. Gastroenterology. 2007;133(1):80–90.
Article
PubMed
Google Scholar
Liu WT, Jing YY, Gao L, Li R, Yang X, Pan XR, et al. Lipopolysaccharide induces the differentiation of hepatic progenitor cells into myofibroblasts constitutes the hepatocarcinogenesis-associated microenvironment. Cell death differentiation. 2020;27(1):85–101.
Article
CAS
PubMed
Google Scholar
Jing Y, Sun K, Liu W, Sheng D, Zhao S, Gao L, et al. Tumor necrosis factor-alpha promotes hepatocellular carcinogenesis through the activation of hepatic progenitor cells. Cancer letters. 2018;434:22–32.
Article
CAS
PubMed
Google Scholar
Li XY, Yang X, Zhao QD, Han ZP, Liang L, Pan XR, et al. Lipopolysaccharide promotes tumorigenicity of hepatic progenitor cells by promoting proliferation and blocking normal differentiation. Cancer Lett. 2017;386:35–46.
Article
CAS
PubMed
Google Scholar
Pan XR, Jing YY, Liu WT, Han ZP, Li R, Yang Y, et al. Lipopolysaccharide induces the differentiation of hepatic progenitor cells into myofibroblasts via activation of the Hedgehog signaling pathway. Cell Cycle. 2017;16(14):1357–65.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kumari P, Ghosh B, Biswas S. Nanocarriers for cancer-targeted drug delivery. J Drug Target. 2016;24(3):179–91.
Article
CAS
PubMed
Google Scholar
Singh A, Shafi S, Upadhyay T, Najmi AK, Kohli K, Pottoo FH. Insights into nanotherapeutic strategies as an impending approach to liver cancer treatment. Curr Topics Med Chem. 2020;20(20):1839–54.
Article
Google Scholar
Piccin A, Murphy W, Smith O. Circulating microparticles: pathophysiology and clinical implications. Blood Rev. 2007;21(3):157–71.
Article
CAS
PubMed
Google Scholar
Mause S, Weber C. Microparticles: protagonists of a novel communication network for intercellular information exchange. Circ Res. 2010;107(9):1047–57.
Article
CAS
PubMed
Google Scholar
Jimenez JJ, Jy W, Mauro LM, Soderland C, Horstman LL, Ahn YS. Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis. Thromb Res. 2003;109(4):175–80.
Article
CAS
PubMed
Google Scholar
Boulanger CM, Scoazec A, Ebrahimian T, Henry P, Mathieu E, Tedgui A, et al. Circulating microparticles from patients with myocardial infarction cause endothelial dysfunction. Circulation. 2001;104(22):2649–52.
Article
CAS
PubMed
Google Scholar
Jansen F, Li Q, Pfeifer A, Werner N. Endothelial- and immune cell-derived extracellular vesicles in the regulation of cardiovascular health and disease. JACC Basic Transl Sci. 2017;2(6):790–807.
Article
PubMed
PubMed Central
Google Scholar
Ratajczak J, Miekus K, Kucia M, Zhang J, Reca R, Dvorak P, et al. Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia. 2006;20(5):847–56.
Article
CAS
PubMed
Google Scholar
Caruso S, Poon IKH. Apoptotic cell-derived extracellular vesicles: more than just debris. Front Immunol. 2018;9:1486.
Article
PubMed
PubMed Central
Google Scholar
Tang K, Zhang Y, Zhang H, Xu P, Liu J, Ma J, et al. Delivery of chemotherapeutic drugs in tumour cell-derived microparticles. Nat Commun. 2012;3:1282.
Article
PubMed
Google Scholar
Liu W, Wang Y, Sun Y, Wu Y, Ma Q, Shi Y, et al. Clonal expansion of hepatic progenitor cells and differentiation into hepatocyte-like cells. Dev Growth Differ. 2019;61(3):203–11.
Article
CAS
PubMed
Google Scholar
Hao PP, Lee MJ, Yu GR, Kim IH, Cho YG, Kim DG. Isolation of EpCAM(+)/CD133 (-) hepatic progenitor cells. Mol Cells. 2013;36(5):424–31.
Article
CAS
PubMed
PubMed Central
Google Scholar
Weiss TS, Lichtenauer M, Kirchner S, Stock P, Aurich H, Christ B, et al. Hepatic progenitor cells from adult human livers for cell transplantation. Gut. 2008;57(8):1129–38.
Article
CAS
PubMed
Google Scholar
Lo RC, Chan KK, Leung CO, Ng IO. Expression of hepatic progenitor cell markers in acute cellular rejection of liver allografts—an immunohistochemical study. Clin Transpl. 2018;32(3):e13203.
Article
Google Scholar
Furuyama K, Kawaguchi Y, Akiyama H, Horiguchi M, Kodama S, Kuhara T, et al. Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet. 2011;43(1):34–41.
Article
CAS
PubMed
Google Scholar
Balaj L, Lessard R, Dai L, Cho YJ, Pomeroy SL, Breakefield XO, et al. Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences. Nat Commun. 2011;2:180.
Article
PubMed
Google Scholar
Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus MC, et al. Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res. 2011;71(15):5346–56.
Article
CAS
PubMed
Google Scholar
Atay S, Banskota S, Crow J, Sethi G, Rink L, Godwin AK. Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion. Proc Natl Acad Sci USA. 2014;111(2):711–6.
Article
CAS
PubMed
Google Scholar
Zhang Y, Zhang R, Zhang H, Liu J, Yang Z, Xu P, et al. Microparticles released by Listeria monocytogenes-infected macrophages are required for dendritic cell-elicited protective immunity. Cell Mol Immunol. 2012;9(6):489–96.
Article
CAS
PubMed
PubMed Central
Google Scholar
Vallhov H, Gutzeit C, Johansson SM, Nagy N, Paul M, Li Q, et al. Exosomes containing glycoprotein 350 released by EBV-transformed B cells selectively target B cells through CD21 and block EBV infection in vitro. J Immunol. 2011;186(1):73–82.
Article
CAS
PubMed
Google Scholar
Deregibus MC, Cantaluppi V, Calogero R, Lo Iacono M, Tetta C, Biancone L, et al. Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA. Blood. 2007;110(7):2440–8.
Article
CAS
PubMed
Google Scholar
Rana S, Yue S, Stadel D, Zoller M. Toward tailored exosomes: the exosomal tetraspanin web contributes to target cell selection. Int J Biochem Cell Biol. 2012;44(9):1574–84.
Article
CAS
PubMed
Google Scholar
Morelli AE, Larregina AT, Shufesky WJ, Sullivan ML, Stolz DB, Papworth GD, et al. Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells. Blood. 2004;104(10):3257–66.
Article
CAS
PubMed
Google Scholar
Levy S, Todd SC, Maecker HT. CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system. Annu Rev Immunol. 1998;16:89–109.
Article
CAS
PubMed
Google Scholar
Savinov AY, Burn P. Interference with islet-specific homing of autoreactive T cells: an emerging therapeutic strategy for type 1 diabetes. Drug Discov Today. 2010;15(13–14):531–9.
Article
CAS
PubMed
Google Scholar
Lemanska-Perek A, Adamik B. Fibronectin and its soluble EDA-FN isoform as biomarkers for inflammation and sepsis. Adv Clin Exp Med. 2019;28(11):1561–7.
Article
PubMed
Google Scholar
Ihara T, Yamamoto T, Sugamata M, Okumura H, Ueno Y. The process of ultrastructural changes from nuclei to apoptotic body. Virchows Archiv. 1998;433(5):443–7.
Article
CAS
PubMed
Google Scholar
Li X, He S, Ma B. Autophagy and autophagy-related proteins in cancer. Mol Cancer. 2020;19(1):12.
Article
CAS
PubMed
PubMed Central
Google Scholar
Atkin-Smith GK, Tixeira R, Paone S, Mathivanan S, Collins C, Liem M, et al. A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure. Nat Commun. 2015;6:7439.
Article
PubMed
Google Scholar
Muhsin-Sharafaldine MR, Saunderson SC, Dunn AC, Faed JM, Kleffmann T, McLellan AD. Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles. Oncotarget. 2016;7(35):56279–94.
Article
PubMed
PubMed Central
Google Scholar
Sun Y, Zheng Z, Zhang H, Yu Y, Ma J, Tang K, et al. Chemotherapeutic tumor microparticles combining low-dose irradiation reprogram tumor-promoting macrophages through a tumor-repopulating cell-curtailing pathway. Oncoimmunology. 2017;6(6):e1309487.
Article
PubMed
PubMed Central
Google Scholar
Pamonsinlapatham P, Gril B, Dufour S, Hadj-Slimane R, Gigoux V, Pethe S, et al. Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration. Cell Signal. 2008;20(11):2119–26.
Article
CAS
PubMed
Google Scholar
Wu Q, Ge W, Chen Y, Kong X, Xian H. PKM2 involved in neuronal apoptosis on hypoxic-ischemic encephalopathy in neonatal rats. Neurochem Res. 2019;44(7):1602–12.
Article
CAS
PubMed
Google Scholar
Marti-Rodrigo A, Alegre F, Moragrega AB, Garcia-Garcia F, Marti-Rodrigo P, Fernandez-Iglesias A, et al. Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells. Gut. 2020;69(5):920–32.
Article
CAS
PubMed
Google Scholar
Scarzello AJ, Romero-Weaver AL, Maher SG, Veenstra TD, Zhou M, Qin A, et al. A mutation in the SH2 domain of STAT2 prolongs tyrosine phosphorylation of STAT1 and promotes type I IFN-induced apoptosis. Mol Biol Cell. 2007;18(7):2455–62.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zhao S, Xiao P, Cui H, Gong P, Lin C, Chen F, et al. Hypothermia-induced ubiquitination of voltage-dependent anion channel 3 protects BV2 microglia cells from cytotoxicity following oxygen-glucose deprivation/recovery. Front Mol Neurosci. 2020;13:100.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chen S, Lv X, Hu B, Shao Z, Wang B, Ma K, et al. RIPK1/RIPK3/MLKL-mediated necroptosis contributes to compression-induced rat nucleus pulposus cells death. Apoptosis. 2017;22(5):626–38.
Article
CAS
PubMed
Google Scholar
Hou XJ, Zhao QD, Jing YY, Han ZP, Yang X, Wei LX, et al. Methylation mediated Gadd45beta enhanced the chemosensitivity of hepatocellular carcinoma by inhibiting the stemness of liver cancer cells. Cell Biosci. 2017;7:63.
Article
PubMed
PubMed Central
Google Scholar
Jia JB, Wang WQ, Sun HC, Zhu XD, Liu L, Zhuang PY, et al. High expression of macrophage colony-stimulating factor-1 receptor in peritumoral liver tissue is associated with poor outcome in hepatocellular carcinoma after curative resection. Oncologist. 2010;15(7):732–43.
Article
CAS
PubMed
PubMed Central
Google Scholar